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Cold atmospheric plasma (CAP) was shown to affect cells not only directly, but also indirectly by means of plasma pre-treated solution. This study investigated a new application of CAP generated in deionized (DI) water for the cancer…

医学物理 · 物理学 2016-10-17 Zhitong Chen , Li Lin , Xiaoqian Cheng , Eda Gjika , Michael Keidar

Cold atmospheric plasma (CAP) has been emerged as a novel technology for cancer treatment. CAP can directly treat cells and tissue but such direct application is limited to skin or can be invoked as a supplement during open surgery. In this…

医学物理 · 物理学 2016-12-21 Zhitong Chen , Xiaoqian Cheng , Li Lin , Michael Keidar

Non-thermal atmospheric plasma (NTAP) can be applied to living tissues and cells as a novel technology for cancer therapy. Even though studies report on the successful use of NTAP to directly irradiate cancer cells, this technology can…

组织与器官 · 定量生物学 2016-09-09 Zhitong Chen , Li Lin , Xiaoqian Cheng , Eda Gjika , Michael Keidar

Hydrogen peroxide (H2O2) is an important signaling molecule in cancer cells. However, the significant secretion of H2O2 by cancer cells have been rarely observed. Cold atmospheric plasma (CAP) is a near room temperature ionized gas composed…

细胞行为 · 定量生物学 2017-07-04 Dayun Yan , Haitao Cui , Wei Zhu , Annie Talbot , Lijie Grace Zhang , Jonathan H. Sherman , Michael Keidar

Cold atmospheric plasma (CAP) has shown its promising application in cancer treatment both in vitro and in vivo. However, the anti-cancer mechanism is still largely unknown. CAP may kill cancer cells via triggering the rise of intracellular…

细胞行为 · 定量生物学 2017-11-27 Dayun Yan , Jonathan H. Sherman , Jerome Canady , Barry Trink , Michael Keidar

In recent years, cold atmospheric plasma (CAP) using inert gas has been successfully applied for biomedicine, such as sterilization, wound healing, skin diseases, and tumor treatment. Here, we reported air cold atmospheric plasma with three…

Through the last decade, cold atmospheric plasma (CAP) has emerged as an innovative therapeutic option for cancer treatment. Recently, we have set up a potentially safe atmospheric pressure plasma jet device that displays antitumoral…

Cold atmospheric plasma (CAP) is a near room temperature ionized gas, generated under non-equilibrium discharge conditions. Here we show that a short exposure of rat peritoneal exudate macrophages and T-cells to CAP in vitro, triggered an…

Cold atmospheric plasmas (CAP) are weakly ionized gases that can be generated in ambient air. They produce energetic species (e.g. electrons, metastables) as well as reactive oxygen species, reactive nitrogen species, UV radiations and…

应用物理 · 物理学 2018-02-21 Florian Judée , Stéphane Simon , Christophe Bailly , Thierry Dufour

Cold atmospheric plasma (CAP) is a promising new agent for (selective) cancer treatment, but the underlying cause of the anti-cancer effect of CAP is not well understood yet. Among different theories and observations, one theory in…

分子网络 · 定量生物学 2020-10-28 Charlotta Bengtson , Annemie Bogaerts

Micro-sized cold atmospheric plasma (uCAP) has been developed to expand the applications of CAP in cancer therapy. In this paper, uCAP devices with different nozzle lengths were applied to investigate effects on both brain (glioblastoma…

组织与器官 · 定量生物学 2018-04-24 Zhitong Chen , Li Lin , Qinmin Zheng , Jonathan H. Sherman , Jerome Canady , Barry Trink , Michael Keidar

For years, extensive efforts have been made to discover effective, non-invasive anti-cancer therapies. Cold atmospheric plasma (CAP), is a near room temperature ionized gas composed of reactive species, charged particles, neutral particles,…

The self-organized pattern (SOP) phenomenon is prevalent in plasma, while knowledge about SOP discharge affecting reactive species generated plasma-activated media (PAM) for cancer therapy is poorly documented. The aim of this study focused…

生物物理 · 物理学 2021-11-04 Zhitong Chen

Plasma medicine is an emerging and innovative interdisciplinary research field combining biology, chemistry, physics, engineering, and medicine. However, the safe clinical application of cold atmospheric plasma (CAP) technology is still a…

医学物理 · 物理学 2023-05-31 Zhitong Chen , Richard Obenchain , Richard E. Wirz

The aim of this study was to investigate the impact of ambient air plasma treatment on both sunflower seed germination and early steps of seedling development under water stress. Dry seeds were exposed to a cold atmospheric plasma (CAP)…

等离子体物理 · 物理学 2025-12-30 L. Taras , C. Bailly , T. Dufour

Cold atmospheric pressure plasma jets (APPJs) are non-equilibrium plasmas, that are capable of producing reactive oxygen and nitrogen species (RONS) at near-room temperature. Their interaction with water leads to the formation of…

等离子体物理 · 物理学 2025-10-30 Syon Bhattacharjee , Deepika Behmani , Sudeep Bhattacharjee

Radio-frequency (RF) driven helicon plasma sources can produce relatively high-density plasmas (n > 10^19 m-3) at relatively moderate powers (< 2 kW) in argon. However, to produce similar high-density plasmas for fusion relevant gases such…

Plasma activated water (PAW) offers a sustainable, nonthermal solution for degrading persistent organic pollutants in industrial effluents. This study employed a gliding arc plasma system to generate PAW for treating diluted waste water…

等离子体物理 · 物理学 2026-01-06 Punit Kumar , Priti Saxena

This study explores the physicochemical modifications and antimicrobial potential of plasma activated saline generated by exposing Sodium Chloride and Ringer solution to atmospheric pressure dielectric barrier discharge plasma. Plasma…

等离子体物理 · 物理学 2026-01-07 Punit Kumar , Priti Saxena

Despite advancements in lung cancer therapy, the prognosis for advanced or metastatic patients remains poor, yet many patients eventually develop resistance to standard treatments leading to disease progression and poor survival. Here, we…

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