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As an important problem in causal inference, we discuss the estimation of treatment effects (TEs). Representing the confounder as a latent variable, we propose Intact-VAE, a new variant of variational autoencoder (VAE), motivated by the…

机器学习 · 统计学 2022-04-22 Pengzhou Wu , Kenji Fukumizu

Building a scalable machine learning system for unsupervised anomaly detection via representation learning is highly desirable. One of the prevalent methods is using a reconstruction error from variational autoencoder (VAE) via maximizing…

机器学习 · 计算机科学 2020-05-08 Seonho Park , George Adosoglou , Panos M. Pardalos

Single-cell perturbation prediction aims to infer how cells respond to unseen interventions and to achieve out-of-distribution (OOD) generalization, providing a computational route to understanding how perturbations reshape cellular…

机器学习 · 计算机科学 2026-05-26 Wenkang Jiang , Yuhang Liu , Erdun Gao , Ehsan Abbasnejad , Lina Yao , Javen Qinfeng Shi

A fully disentangled variational auto-encoder (VAE) aims to identify disentangled latent components from observations. However, enforcing full independence between all latent components may be too strict for certain datasets. In some cases,…

机器学习 · 计算机科学 2025-02-05 Chengrui Li , Yunmiao Wang , Yule Wang , Weihan Li , Dieter Jaeger , Anqi Wu

When training end-to-end learned models for lossy compression, one has to balance the rate and distortion losses. This is typically done by manually setting a tradeoff parameter $\beta$, an approach called $\beta$-VAE. Using this approach…

机器学习 · 计算机科学 2020-05-11 Ties van Rozendaal , Guillaume Sautière , Taco S. Cohen

Wastewater-based genomic surveillance has emerged as a powerful tool for population-level viral monitoring, offering comprehensive insights into circulating viral variants across entire communities. However, this approach faces significant…

机器学习 · 计算机科学 2025-12-04 Adele Chinda , Richmond Azumah , Hemanth Demakethepalli Venkateswara

This paper provides a comprehensive analysis of variational inference in latent variable models for survival analysis, emphasizing the distinctive challenges associated with applying variational methods to survival data. We identify a…

机器学习 · 计算机科学 2025-06-05 Chuanhui Liu , Xiao Wang

We decompose the evidence lower bound to show the existence of a term measuring the total correlation between latent variables. We use this to motivate our $\beta$-TCVAE (Total Correlation Variational Autoencoder), a refinement of the…

机器学习 · 计算机科学 2019-04-24 Ricky T. Q. Chen , Xuechen Li , Roger Grosse , David Duvenaud

Latent variable models like the Variational Auto-Encoder (VAE) are commonly used to learn representations of images. However, for downstream tasks like semantic classification, the representations learned by VAE are less competitive than…

机器学习 · 统计学 2022-05-31 Mingtian Zhang , Tim Z. Xiao , Brooks Paige , David Barber

Deep latent variable models (LVM) such as variational auto-encoder (VAE) have recently played an important role in text generation. One key factor is the exploitation of smooth latent structures to guide the generation. However, the…

机器学习 · 计算机科学 2019-12-02 Le Fang , Chunyuan Li , Jianfeng Gao , Wen Dong , Changyou Chen

This paper challenges the common assumption that the weight $\beta$, in $\beta$-VAE, should be larger than $1$ in order to effectively disentangle latent factors. We demonstrate that $\beta$-VAE, with $\beta < 1$, can not only attain good…

机器学习 · 计算机科学 2020-10-02 Huajie Shao , Haohong Lin , Qinmin Yang , Shuochao Yao , Han Zhao , Tarek Abdelzaher

Variational autoencoders (VAEs) have been widely applied for text modeling. In practice, however, they are troubled by two challenges: information underrepresentation and posterior collapse. The former arises as only the last hidden state…

机器学习 · 计算机科学 2021-06-17 Xianghong Fang , Haoli Bai , Jian Li , Zenglin Xu , Michael Lyu , Irwin King

Variational Autoencoders (VAE) and their variants have been widely used in a variety of applications, such as dialog generation, image generation and disentangled representation learning. However, the existing VAE models have some…

机器学习 · 计算机科学 2020-06-23 Huajie Shao , Shuochao Yao , Dachun Sun , Aston Zhang , Shengzhong Liu , Dongxin Liu , Jun Wang , Tarek Abdelzaher

We present two deep generative models based on Variational Autoencoders to improve the accuracy of drug response prediction. Our models, Perturbation Variational Autoencoder and its semi-supervised extension, Drug Response Variational…

机器学习 · 统计学 2017-07-07 Ladislav Rampasek , Daniel Hidru , Petr Smirnov , Benjamin Haibe-Kains , Anna Goldenberg

This paper reviews the novel concept of controllable variational autoencoder (ControlVAE), discusses its parameter tuning to meet application needs, derives its key analytic properties, and offers useful extensions and applications.…

机器学习 · 计算机科学 2020-11-04 Huajie Shao , Zhisheng Xiao , Shuochao Yao , Aston Zhang , Shengzhong Liu , Tarek Abdelzaher

Classical methods for model order selection often fail in scenarios with low SNR or few snapshots. Deep learning-based methods are promising alternatives for such challenging situations as they compensate lack of information in the…

信号处理 · 电气工程与系统科学 2023-12-07 Michael Baur , Franz Weißer , Benedikt Böck , Wolfgang Utschick

Variational autoencoders (VAEs) are among leading approaches to address the problem of learning disentangled representations. Typically a single VAE is used and disentangled representations are sought within its single continuous latent…

机器学习 · 统计学 2026-04-02 Veranika Boukun , Jörg Lücke

In the real-world data, there are common variations shared by all classes (e.g. category label) and exclusive variations of each class. We propose a variant of VAE capable of disentangling both of these variations. To represent these…

机器学习 · 计算机科学 2021-06-18 Jaewoong Choi , Geonho Hwang , Myungjoo Kang

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

机器学习 · 计算机科学 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Analysis of cardiac ultrasound images is commonly performed in routine clinical practice for quantification of cardiac function. Its increasing automation frequently employs deep learning networks that are trained to predict disease or…

计算机视觉与模式识别 · 计算机科学 2021-08-09 Agisilaos Chartsias , Shan Gao , Angela Mumith , Jorge Oliveira , Kanwal Bhatia , Bernhard Kainz , Arian Beqiri