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Following the recent interest in applying the Hyperdimensional Computing paradigm in medical context to power up the performance of general machine learning applied to biomedical data, this study represents the first attempt at employing…

信号处理 · 电气工程与系统科学 2025-01-10 Federica Colonnese , Antonello Rosato , Francesco Di Luzio , Massimo Panella

Background: Previous functional connectivity studies have found both hypo- and hyper-connectivity in brains of individuals having autism spectrum disorder (ASD). Here we studied abnormalities in functional brain subnetworks in…

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

统计方法学 · 统计学 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

Existing deep learning models for functional MRI-based classification have limitations in network architecture determination (relying on experience) and feature space fusion (mostly simple concatenation, lacking mutual learning). Inspired…

机器学习 · 计算机科学 2025-08-19 Xiangxiang Cui , Min Zhao , Dongmei Zhi , Shile Qi , Vince D Calhoun , Jing Sui

Self Supervised Representation Learning (SSRepL) can capture meaningful and robust representations of the Attention Deficit Hyperactivity Disorder (ADHD) data and have the potential to improve the model's performance on also downstream…

机器学习 · 计算机科学 2025-02-04 Abdul Rehman , Ilona Heldal , Jerry Chun-Wei Lin

Some evidence suggests that people with autism spectrum disorder exhibit patterns of brain functional dysconnectivity relative to their typically developing peers, but specific findings have yet to be replicated. To facilitate this…

统计方法学 · 统计学 2025-03-03 Hyoshin Kim , Sujit K. Ghosh , Emily C. Hector

Population imaging markedly increased the size of functional-imaging datasets, shedding new light on the neural basis of inter-individual differences. Analyzing these large data entails new scalability challenges, computational and…

Functional magnetic resonance imaging (fMRI) functional connectivity between brain regions is often computed using parcellations defined by functional or structural atlases. Typically, some kind of voxel averaging is performed to obtain a…

Attention Deficit Hyperactivity Disorder (ADHD) is a common brain disorder in children that can persist into adulthood, affecting social, academic, and career life. Early diagnosis is crucial for managing these impacts on patients and the…

机器学习 · 计算机科学 2025-09-11 Ali Amini , Mohammad Alijanpour , Behnam Latifi , Ali Motie Nasrabadi

Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…

神经元与认知 · 定量生物学 2025-09-24 Ali Khazaee , Abdolreza Mohammadi , Ruairi O'Reilly

Autism spectrum disorder (ASD) affects the brain connectivity at different levels. Nonetheless, non-invasively distinguishing such effects using magnetic resonance imaging (MRI) remains very challenging to machine learning diagnostic…

机器学习 · 计算机科学 2020-04-29 Ismail Bilgen , Goktug Guvercin , Islem Rekik

The brain is often studied from a network perspective, where functional activity is assessed using functional Magnetic Resonance Imaging (fMRI) to estimate connectivity between predefined neuronal regions. Functional connectivity can be…

应用统计 · 统计学 2025-07-22 Olivier Bisson , Yanis Aeschlimann , Samuel Deslauriers-Gauthier , Xavier Pennec

Analysis and quantification of brain structural changes, using Magnetic resonance imaging (MRI), are increasingly used to define novel biomarkers of brain pathologies, such as Alzheimer's disease (AD). Network-based models of the brain have…

Resting-state functional magnetic resonance imaging (rs-fMRI)-derived functional connectivity patterns have been extensively utilized to delineate global functional organization of the human brain in health, development, and…

定量方法 · 定量生物学 2020-10-02 Li Xiao , Biao Cai , Gang Qu , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Alzheimer's Disease (AD) is a currently incurable neurodegeneartive disease. Accurately detecting AD, especially in the early stage, represents a high research priority. AD is characterized by progressive cognitive impairments that are…

机器学习 · 计算机科学 2024-08-08 Wenqi Zhu , Yinghua Fu , Ze Wang

Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

神经元与认知 · 定量生物学 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

Large Language Models (LLMs) have demonstrated strong semantic reasoning across multimodal domains. However, their integration with graph-based models of brain connectivity remains limited. In addition, most existing fMRI analysis methods…

图像与视频处理 · 电气工程与系统科学 2026-05-27 Yasaman Torabi , Parsa Razmara , Hamed Ajorlou , Bardia Baraeinejad

To explain individual differences in development, behavior, and cognition, most previous studies focused on projecting resting-state functional MRI (fMRI) based functional connectivity (FC) data into a low-dimensional space via linear…

神经元与认知 · 定量生物学 2018-11-01 Li Xiao , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

The objective of this study is to derive functional networks for the autism spectrum disorder (ASD) population using the group ICA and dictionary learning model together and to classify ASD and typically developing (TD) participants using…

神经元与认知 · 定量生物学 2021-06-17 Xin Yang , Ning Zhang , Donglin Wang

Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and…

机器学习 · 计算机科学 2016-12-06 Colin J Brown , Ghassan Hamarneh