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We propose a Noise Entangled GAN (NE-GAN) for simulating low-dose computed tomography (CT) images from a higher dose CT image. First, we present two schemes to generate a clean CT image and a noise image from the high-dose CT image. Then,…

图像与视频处理 · 电气工程与系统科学 2021-02-22 Chuang Niu , Ge Wang , Pingkun Yan , Juergen Hahn , Youfang Lai , Xun Jia , Arjun Krishna , Klaus Mueller , Andreu Badal , KyleJ. Myers , Rongping Zeng

Tumor segmentation in medical imaging is crucial and relies on precise delineation. Fluorodeoxyglucose Positron-Emission Tomography (FDG-PET) is widely used in clinical practice to detect metabolically active tumors. However, FDG-PET scans…

图像与视频处理 · 电气工程与系统科学 2023-10-05 Matthias Hadlich , Zdravko Marinov , Rainer Stiefelhagen

We investigate subset-based optimization methods for positron emission tomography (PET) image reconstruction incorporating a regularizing prior. PET reconstruction methods that use a prior, such as the relative difference prior (RDP), are…

医学物理 · 物理学 2025-06-06 Matthias J. Ehrhardt , Zeljko Kereta , Georg Schramm

In minimally-invasive brain surgeries with indirect and narrow operating environments, 3D brain reconstruction is crucial. However, as requirements of accuracy for some new minimally-invasive surgeries (such as brain-computer interface…

图像与视频处理 · 电气工程与系统科学 2025-03-26 Bowen Hu , Weiheng Yao , Sibo Qiao , Hieu Pham , Shuqiang Wang , Michael Kwok-Po Ng

Medical Image-to-image translation is a key task in computer vision and generative artificial intelligence, and it is highly applicable to medical image analysis. GAN-based methods are the mainstream image translation methods, but they…

图像与视频处理 · 电气工程与系统科学 2023-11-07 Zhuhui Wang , Jianwei Zuo , Xuliang Deng , Jiajia Luo

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

图像与视频处理 · 电气工程与系统科学 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

Multiphase contrast-enhanced computed tomography (CECT) scan is clinically significant to demonstrate the anatomy at different phases. In practice, such a multiphase CECT scan inherently takes longer time and deposits much more radiation…

图像与视频处理 · 电气工程与系统科学 2023-06-14 Rongjun Ge , Yuting He , Cong Xia , Yang Chen , Daoqiang Zhang , Ge Wang

Positron emission tomography (PET) reconstruction is a critical challenge in molecular imaging, often hampered by noise amplification, structural blurring, and detail loss due to sparse sampling and the ill-posed nature of inverse problems.…

计算机视觉与模式识别 · 计算机科学 2026-02-13 Mengxiao Geng , Zijie Chen , Ran Hong , Bingxuan Li , Qiegen Liu

Positron Emission Tomography (PET) is an imaging method that can assess physiological function rather than structural disturbances by measuring cerebral perfusion or glucose consumption. However, this imaging technique relies on injection…

图像与视频处理 · 电气工程与系统科学 2021-03-10 Sahar Yousefi , Hessam Sokooti , Wouter M. Teeuwisse , Dennis F. R. Heijtel , Aart J. Nederveen , Marius Staring , Matthias J. P. van Osch

Recently, paired (e.g. Pix2pix) and unpaired (e.g. CycleGAN) image-to-image translation methods have shown effective in medical imaging tasks. In practice, however, it can be difficult to apply these deep models on medical data volumes,…

图像与视频处理 · 电气工程与系统科学 2019-08-02 Tycho F. A. van der Ouderaa , Daniel E. Worrall , Bram van Ginneken

Although supervised convolutional neural networks (CNNs) often outperform conventional alternatives for denoising positron emission tomography (PET) images, they require many low- and high-quality reference PET image pairs. Herein, we…

Patlak model is widely used in 18F-FDG dynamic positron emission tomography (PET) imaging, where the estimated parametric images reveal important biochemical and physiology information. Because of better noise modeling and more information…

医学物理 · 物理学 2020-09-15 Nuobei Xie , Kuang Gong , Ning Guo , Zhixing Qin , Jianan Cui , Zhifang Wu , Huafeng Liu , Quanzheng Li

Deep learning based PET image reconstruction methods have achieved promising results recently. However, most of these methods follow a supervised learning paradigm, which rely heavily on the availability of high-quality training labels. In…

图像与视频处理 · 电气工程与系统科学 2023-03-13 Rui Hu , Yunmei Chen , Kyungsang Kim , Marcio Aloisio Bezerra Cavalcanti Rockenbach , Quanzheng Li , Huafeng Liu

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

图像与视频处理 · 电气工程与系统科学 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Fusing multi-modality medical images, such as MR and PET, can provide various anatomical or functional information about human body. But PET data is always unavailable due to different reasons such as cost, radiation, or other limitations.…

图像与视频处理 · 电气工程与系统科学 2020-08-11 Shengye Hu , Baiying Lei , Yong Wang , Zhiguang Feng , Yanyan Shen , Shuqiang Wang

Parametric imaging is a compartmental approach that processes nuclear imaging data to estimate the spatial distribution of the kinetic parameters governing tracer flow. The present paper proposes a novel and efficient computational method…

The Computed Tomography (CT) for diagnosis of lesions in human internal organs is one of the most fundamental topics in medical imaging. Low-dose CT, which offers reduced radiation exposure, is preferred over standard-dose CT, and therefore…

图像与视频处理 · 电气工程与系统科学 2023-09-26 Wenjie Liu

Low-dose Positron Emission Tomography (PET) reduces radiation exposure but suffers from severe noise and quantitative degradation. Diffusion-based denoising models achieve strong final reconstructions, yet their reverse trajectories are…

Low-count positron emission tomography (PET) reconstruction is a challenging inverse problem due to severe degradations arising from Poisson noise, photon scarcity, and attenuation correction errors. Existing deep learning methods typically…

图像与视频处理 · 电气工程与系统科学 2026-04-09 Zheng Zhang , Hao Tang , Yingying Hu , Zhanli Hu , Jing Qin

Our aim was to enhance visual quality and quantitative accuracy of dynamic positron emission tomography (PET)uptake images by improved image reconstruction, using sophisticated sparse penalty models that incorporate both 2D spatial+1D…

计算机视觉与模式识别 · 计算机科学 2019-06-17 Ida Häggström , Yizun Lin , Si Li , Andrzej Krol , Yuesheng Xu , C. Ross Schmidtlein