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Medical image registration and segmentation are two of the most frequent tasks in medical image analysis. As these tasks are complementary and correlated, it would be beneficial to apply them simultaneously in a joint manner. In this paper,…

图像与视频处理 · 电气工程与系统科学 2021-05-06 Mohamed S. Elmahdy , Laurens Beljaards , Sahar Yousefi , Hessam Sokooti , Fons Verbeek , U. A. van der Heide , Marius Staring

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its…

Purpose: Organ-at-risk (OAR) delineation is a key step for cone-beam CT (CBCT) based adaptive radiotherapy planning that can be a time-consuming, labor-intensive, and subject-to-variability process. We aim to develop a fully automated…

Near infrared diffuse optical tomography (DOT) provides an imaging modality for the oxygenation of tissue. In this paper, we propose a novel machine learning algorithm based on time-domain radiative transfer equation. We use temporal…

医学物理 · 物理学 2020-11-26 Yu-ichi Takamizu , Masayuki Umemura , Hidenobu Yajima , Makito Abe , Yoko Hoshi

Medical image segmentation is a pivotal task within the realms of medical image analysis and computer vision. While current methods have shown promise in accurately segmenting major regions of interest, the precise segmentation of boundary…

图像与视频处理 · 电气工程与系统科学 2025-05-09 Yi Lin , Dong Zhang , Xiao Fang , Yufan Chen , Kwang-Ting Cheng , Hao Chen

Multiresolution topology optimization (MTO) methods involve decoupling of the design and analysis discretizations, such that a high-resolution design can be obtained at relatively low analysis costs. Recent studies have shown that the MTO…

计算工程、金融与科学 · 计算机科学 2018-11-27 Deepak K. Gupta , Fred van Keulen , Matthijs Langelaar

Purposes: This study aimed to develop a computed tomography (CT)-based multi-organ segmentation model for delineating organs-at-risk (OARs) in pediatric upper abdominal tumors and evaluate its robustness across multiple datasets. Materials…

Adaptive Radiotherapy (ART) is an emerging technique for treating cancer patients which facilitates higher delivery accuracy and has the potential to reduce toxicity. However, ART is also resource-intensive, requiring extra human and…

医学物理 · 物理学 2022-12-20 Rupesh Ghimire , Kevin L. Moore , Daniela Branco , Dominique L. Rash , Jyoti Mayadev , Xenia Ray

Automatic brain tumor segmentation plays an important role for diagnosis, surgical planning and treatment assessment of brain tumors. Deep convolutional neural networks (CNNs) have been widely used for this task. Due to the relatively small…

计算机视觉与模式识别 · 计算机科学 2019-02-26 Guotai Wang , Wenqi Li , Sebastien Ourselin , Tom Vercauteren

In the realm of medical science, the pursuit of enhancing treatment efficacy and patient outcomes continues to drive innovation. This study delves into the integration of biomimicry principles within the domain of Radiation Therapy (RT) to…

神经与进化计算 · 计算机科学 2025-01-07 Keshav Kumar K. , NVSL Narasimham

Over the last ten years, Patient-Derived Organoids (PDOs) emerged as the most reliable technology to generate ex-vivo tumor avatars. PDOs retain the main characteristics of their original tumor, making them a system of choice for…

Sparse-view Computed Tomography (CT) reconstructs images from a limited number of X-ray projections to reduce radiation and scanning time, which makes reconstruction an ill-posed inverse problem. Deep learning methods achieve high-fidelity…

图像与视频处理 · 电气工程与系统科学 2025-12-16 Aujasvit Datta , Jiayun Wang , Asad Aali , Armeet Singh Jatyani , Anima Anandkumar

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

医学物理 · 物理学 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Transformer models have demonstrated the capability to produce highly accurate segmentation of organs and tumors. However, model training requires high-quality curated datasets to ensure robust generalization to unseen datasets. Hence, we…

We evaluated the temporal performance of a deep learning (DL) based artificial intelligence (AI) model for auto segmentation in prostate radiotherapy, seeking to correlate its efficacy with changes in clinical landscapes. Our study involved…

图像与视频处理 · 电气工程与系统科学 2023-11-17 Biling Wang , Michael Dohopolski , Ti Bai , Junjie Wu , Raquibul Hannan , Neil Desai , Aurelie Garant , Daniel Yang , Dan Nguyen , Mu-Han Lin , Robert Timmerman , Xinlei Wang , Steve Jiang

It is possible to find the optimized radiation dose per session for a radiotherapy (RT) treatment, using a population dynamics model. This has already been done in a previous work for a protocol with 30 sessions and a fixed dose per…

Numerous oncology indications have extensively quantified metabolically active tumors using positron emission tomography (PET) and computed tomography (CT). F-fluorodeoxyglucose-positron emission tomography (FDG-PET) is frequently utilized…

图像与视频处理 · 电气工程与系统科学 2022-10-17 Sepideh Amiri , Bulat Ibragimov

Medical image segmentation is a fundamental task in the community of medical image analysis. In this paper, a novel network architecture, referred to as Convolution, Transformer, and Operator (CTO), is proposed. CTO employs a combination of…

计算机视觉与模式识别 · 计算机科学 2023-05-02 Yi Lin , Dong Zhang , Xiao Fang , Yufan Chen , Kwang-Ting Cheng , Hao Chen

Online adaptive radiation therapy (ART) promises the ability to deliver an optimal treatment in response to daily patient anatomic variation. A major technical barrier for the clinical implementation of online ART is the requirement of…

We propose an oAPT workflow that incorporates all these functionalities and validate its clinical implementation feasibility with prostate patients. AI-based auto-segmentation tool AccuContourTM (Manteia, Xiamen, China) was seamlessly…