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Microplate-based 'omic studies of large clinical cohorts can massively accelerate biomedical research, but experimental power and veracity may be negatively impacted when plate positional effects confound clinical variables of interest.…

定量方法 · 定量生物学 2026-01-09 Avigail Taylor , Micah P. Fletcher

An improved numerical solver for the unified solution of compressible and incompressible fluids involving interfaces is proposed. The present method is based on the CIP-CUP (Cubic Interpolated Propagation / Combined, Unified Procedure)…

计算物理 · 物理学 2007-05-23 Masato Ida

Tip enhanced IR spectra and imaging have been widely used in cutting-edge studies for the in-depth understanding of the composition, structure and function of interfaces at the nanoscale. However, molecular monolayer sensitivity has only…

Mid-infrared spectroscopy offers powerful label-free molecular analysis capabilities but faces significant challenges when analyzing complex biological samples. Here, we present a transformative surface-enhanced infrared absorption…

We propose AttentionMixer, a unified deep learning framework for multimodal detection of brain edema that combines structural head CT (HCT) with routine clinical metadata. While HCT provides rich spatial information, clinical variables such…

Mid-infrared absorption spectroscopy is a well-established technique for non-destructive quantitative molecular analysis. Waveguide-integrated sensors provide a particularly compact solution operating with reduced sample volumes while…

光学 · 物理学 2024-08-16 Antonia Torres-Cubillo , Andrea Teuber , Robert Halir , Boris Mizaikoff

Exploring novel materials with enhanced optical nonlinearities at low power levels with ultrafast response and small footprints is of great interests for information processing, communication, sensing and quantum systems. Recent progress on…

光学 · 物理学 2023-05-23 Md Zubair Ebne Rafique , Ali Basiri , Jing Bai , Jiawei Zuo , Yu Yao

Efficient transportation and delivery of analytes to the surface of optical sensors are crucial for overcoming limitations in diffusion-limited transport and analyte sensing. In this study, we propose a novel approach that combines…

光学 · 物理学 2024-01-31 Chuchuan Hong , Ikjun Hong , Sen Yang , Justus C. Ndukaife

Dielectric metasurfaces have introduced a new paradigm for substance detection by exploiting their resonant properties to enhance light-matter interaction. This enhancement can be used for sensing either through refractive index changes or…

Recent developments in machine learning interatomic potentials (MLIPs) have empowered even non-experts in machine learning to train MLIPs for accelerating materials simulations. However, the current literature lacks clear standards for…

化学物理 · 物理学 2024-01-05 Tristan Maxson , Ademola Soyemi , Benjamin W. J. Chen , Tibor Szilvási

Triply Periodic Minimal Surface (TPMS) structures have emerged as a new class of porous materials with variable geometries and favourable transport properties, making them promising for reactor internals in chemical engineering. However,…

Recent semi-dense image matching methods have achieved remarkable success, but two long-standing issues still impair their performance. At the coarse stage, the over-exclusion issue of their mutual nearest neighbor (MNN) matching layer…

计算机视觉与模式识别 · 计算机科学 2026-04-09 Ke Jin , Jiming Chen , Qi Ye

Soft particles display highly versatile properties with respect to hard colloids, even more so at fluid-fluid interfaces. In particular, microgels, consisting of a cross-linked polymer network, are able to deform and flatten upon adsorption…

Heteropolymer gels can be engineered to release specific molecules into or absorb molecules from a surrounding solution. This remarkable ability is the basis for developing gel applications in extensive areas such as drug delivery, waste…

A hitherto unexploited characteristic feature of emerging iontronic devices for information processing is the intrinsic mobility of the medium (water) of dissolved ions in aqueous electrolytes, which therefore not only respond to voltage…

软凝聚态物质 · 物理学 2024-04-24 A. Barnaveli , T. M. Kamsma , W. Q. Boon , R. van Roij

Machine learning interatomic potentials (MLIPs) are an emerging modeling technique that promises to provide electronic structure theory accuracy for a fraction of its cost, however, the transferability of MLIPs is a largely unknown factor.…

化学物理 · 物理学 2024-02-27 Tristan Maxson , Tibor Szilvasi

The need to use a short time step is a key limit on the speed of molecular dynamics (MD) simulations. Simulations governed by classical potentials are often accelerated by using a multiple-time-step (MTS) integrator that evaluates certain…

化学物理 · 物理学 2023-10-24 Xiang Fu , Albert Musaelian , Anders Johansson , Tommi Jaakkola , Boris Kozinsky

Machine learning interatomic potentials (MLIPs) are one of the main techniques in the materials science toolbox, able to bridge ab initio accuracy with the computational efficiency of classical force fields. This allows simulations ranging…

材料科学 · 物理学 2025-03-20 Bruno Focassio , Luis Paulo Mezzina Freitas , Gabriel R. Schleder

Probe-level models have led to improved performance in microarray studies but the various sources of probe-level contamination are still poorly understood. Data-driven analysis of probe performance can be used to quantify the uncertainty in…

计算工程、金融与科学 · 计算机科学 2013-04-09 Leo Lahti , Laura L. Elo , Tero Aittokallio , Samuel Kaski

As one of the most prevalent diseases worldwide, plaque formation in human arteries, known as atherosclerosis, is the focus of many research efforts. Previously, molecular communication (MC) models have been proposed to capture and analyze…