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相关论文: Optimal fenestration of the Fontan circulation

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Accurate simulations of the flow in the human airway are essential for advancing diagnostic methods. Many existing computational studies rely on simplified geometries or turbulence models, limiting their simulation's ability to resolve flow…

In order to provide comfort in a low energy consumption building, it is preferable to use natural ventilation rather than HVAC systems. To achieve this, engineers need tools that predict the heat and mass transfers between the building's…

流体动力学 · 物理学 2012-12-24 Alain Bastide , Francis Allard , Harry Boyer

This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the…

We build an evolutionary scenario that explains how some crucial physiological constraints in the arterial network of mammals - i.e. hematocrit, vessels diameters and arterial pressure drops - could have been selected by evolution. We…

生物物理 · 物理学 2014-05-22 Baptiste Moreau , Benjamin Mauroy

Fontan operation as the current standard of care for the palliation of single ventricle defects results in significant late complications. Using a mechanical circulatory device for the right circulation to serve the function of the missing…

定量方法 · 定量生物学 2020-02-18 Masoud Farahmand , Minoo N. Kavarana , Phillip M. Trusty , Ethan O. Kung

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

流体动力学 · 物理学 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

We numerically investigate the influence of flow development on secondary flow patterns and subsequent wall shear stress distributions in a curved artery model, and we compute vascular metrics commonly used to assess variations in blood…

流体动力学 · 物理学 2022-09-20 Christopher Cox , Michael W. Plesniak

Reversed Potts shunt (PS) was suggested as palliation for patients with suprasystemic pulmonary arterial hypertension (PAH) and right ventricular (RV) failure. PS, however, can result in poorly understood mortality. Here, a patient-specific…

We develop two mathematical lumped parameter models for blood pressure distribution in the Fontan blood flow circulation: an ODE based spatially homogeneous model and a PDE based spatially inhomogeneous model. We present numerical…

偏微分方程分析 · 数学 2018-06-08 J. P. Keener , M. Chugunova , R. M. Taranets , M. G. Doyle

We numerically investigate the effect of entrance condition on the spatial and temporal evolution of multiple three-dimensional vortex pairs and wall shear stress distribution in a curved artery model. We perform this study using a…

流体动力学 · 物理学 2021-11-10 Christopher Cox , Michael W. Plesniak

Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed…

计算物理 · 物理学 2008-02-19 Renat A. Sultanov , Dennis Guster , Brent Engelbrekt , Richard Blankenbecler

Fontan patients often develop circulatory failure and are in desperate need of a therapeutic solution. A blood pump surgically placed in the cavopulmonary pathway can substitute the function of the absent sub-pulmonary ventricle by…

组织与器官 · 定量生物学 2019-04-19 Masoud Farahmand , Minoo N. Kavarana , Ethan O. Kung

We describe a simple experiment involving spheres rolling down an inclined plane towards a bottleneck and through a gap. Results of the experiment indicate that flow rate can be increased by placing an obstruction at optimal positions near…

软凝聚态物质 · 物理学 2017-03-23 Alan Murray , Fernando Alonso-Marroquin

Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…

定量方法 · 定量生物学 2020-02-21 Megan J. Chambers , Mitchel J. Colebank , M Umar Qureshi , Rachel Clipp , Mette S. Olufsen

With an aim to investigate the effect of externally imposed body acceleration and magnetic field on pulsatile flow of blood through an arterial segment having stenosis is under consideration in this paper. The flow of blood is presented by…

数值分析 · 数学 2012-09-25 G. C. Shit , M. Roy

Air curtains are installed in open doorways of a building to reduce buoyancy-driven exchange flows across the doorway. Although an air curtain allows an unhampered passage of humans and vehicles, the interaction of this traffic with an air…

流体动力学 · 物理学 2020-09-15 Narsing K. Jha , D. Frank , L. Darracq , P. F. Linden

During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we simulate blood flow and oxygen transfer in feto-placental capillaries by converting three-dimensional representations of…

We present a stream-tube model of oxygen exchange inside a human placenta functional unit (a placentone). The effect of villi density on oxygen transfer efficiency is assessed by numerically solving the diffusion-convection equation in a…

定量方法 · 定量生物学 2015-01-05 A. S. Serov , C. Salafia , P. Brownbill , D. S. Grebenkov , M. Filoche

The aortic valve is a three-leaflet passive structure that, driven by pressure differences between the left ventricle and the aorta, opens and closes during the heartbeat to ensure the correct stream direction and flow rate. In elderly…

流体动力学 · 物理学 2021-03-30 Francesco Viola , Valentina Meschini , Roberto Verzicco

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

流体动力学 · 物理学 2008-11-11 Renat A. Sultanov , Dennis Guster
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