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Multi-omics data is increasingly being utilized to advance computational methods for cancer classification. However, multi-omics data integration poses significant challenges due to the high dimensionality, data complexity, and distinct…

基因组学 · 定量生物学 2024-10-10 Fadi Alharbi , Aleksandar Vakanski , Boyu Zhang , Murtada K. Elbashir , Mohanad Mohammed

Multimodal survival methods combining gigapixel histology whole-slide images (WSIs) and transcriptomic profiles are particularly promising for patient prognostication and stratification. Current approaches involve tokenizing the WSIs into…

计算机视觉与模式识别 · 计算机科学 2024-07-02 Andrew H. Song , Richard J. Chen , Guillaume Jaume , Anurag J. Vaidya , Alexander S. Baras , Faisal Mahmood

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Classification using multimodal data arises in many machine learning applications. It is crucial not only to model cross-modal relationship effectively but also to ensure robustness against loss of part of data or modalities. In this paper,…

机器学习 · 计算机科学 2019-04-22 Jun-Ho Choi , Jong-Seok Lee

Multimodal fusion has emerged as a promising paradigm for disease diagnosis and prognosis, integrating complementary information from heterogeneous data sources such as medical images, clinical records, and radiology reports. However,…

Domain generalization in computational histopathology is hindered by heterogeneity in whole slide images (WSIs), caused by variations in tissue preparation, staining, and imaging conditions across institutions. Unlike machine learning…

计算机视觉与模式识别 · 计算机科学 2025-09-03 Hikmat Khan , Syed Farhan Alam Zaidi , Pir Masoom Shah , Kiruthika Balakrishnan , Rabia Khan , Muhammad Waqas , Jia Wu

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

图像与视频处理 · 电气工程与系统科学 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

图像与视频处理 · 电气工程与系统科学 2024-03-01 Ha Anh Vu

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

图像与视频处理 · 电气工程与系统科学 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Prediction tasks in digital pathology are challenging due to the massive size of whole-slide images (WSIs) and the weak nature of training signals. Advances in computing, data availability, and self-supervised learning (SSL) have paved the…

图像与视频处理 · 电气工程与系统科学 2026-02-02 Vishwesh Ramanathan , Tony Xu , Pushpak Pati , Faruk Ahmed , Maged Goubran , Anne L. Martel

Accurate survival prediction is essential for personalized cancer treatment. However, genomic data - often a more powerful predictor than pathology data - is costly and inaccessible. We present the cross-modal genomic feature translation…

图像与视频处理 · 电气工程与系统科学 2024-11-04 Akhila Krishna , Nikhil Cherian Kurian , Abhijeet Patil , Amruta Parulekar , Amit Sethi

We present BioLangFusion, a simple approach for integrating pre-trained DNA, mRNA, and protein language models into unified molecular representations. Motivated by the central dogma of molecular biology (information flow from gene to…

机器学习 · 计算机科学 2025-06-11 Amina Mollaysa , Artem Moskale , Pushpak Pati , Tommaso Mansi , Mangal Prakash , Rui Liao

Deep learning models, such as the fully convolutional network (FCN), have been widely used in 3D biomedical segmentation and achieved state-of-the-art performance. Multiple modalities are often used for disease diagnosis and quantification.…

图像与视频处理 · 电气工程与系统科学 2019-08-23 Yu Chen , Jiawei Chen , Dong Wei , Yuexiang Li , Yefeng Zheng

Due to the severe lack of labeled data, existing methods of medical visual question answering usually rely on transfer learning to obtain effective image feature representation and use cross-modal fusion of visual and linguistic features to…

多媒体 · 计算机科学 2021-05-04 Haifan Gong , Guanqi Chen , Sishuo Liu , Yizhou Yu , Guanbin Li

Learning medical visual representations directly from paired radiology reports has become an emerging topic in representation learning. However, existing medical image-text joint learning methods are limited by instance or local supervision…

计算机视觉与模式识别 · 计算机科学 2022-10-13 Fuying Wang , Yuyin Zhou , Shujun Wang , Varut Vardhanabhuti , Lequan Yu

Recently, multimodal deep learning, which integrates histopathology slides and molecular biomarkers, has achieved a promising performance in glioma grading. Despite great progress, due to the intra-modality complexity and inter-modality…

计算机视觉与模式识别 · 计算机科学 2024-08-19 Li Pan , Yupei Zhang , Qiushi Yang , Tan Li , Xiaohan Xing , Maximus C. F. Yeung , Zhen Chen

Multi-modal learning focuses on training models by equally combining multiple input data modalities during the prediction process. However, this equal combination can be detrimental to the prediction accuracy because different modalities…

计算机视觉与模式识别 · 计算机科学 2022-07-25 Hu Wang , Jianpeng Zhang , Yuanhong Chen , Congbo Ma , Jodie Avery , Louise Hull , Gustavo Carneiro

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to…

图像与视频处理 · 电气工程与系统科学 2021-09-15 Yuchen Fei , Bo Zhan , Mei Hong , Xi Wu , Jiliu Zhou , Yan Wang

Multi-modality is widely used in medical imaging, because it can provide multiinformation about a target (tumor, organ or tissue). Segmentation using multimodality consists of fusing multi-information to improve the segmentation. Recently,…

图像与视频处理 · 电气工程与系统科学 2020-07-17 Tongxue Zhou , Su Ruan , Stéphane Canu

Multi-modality image fusion and segmentation play a vital role in autonomous driving and robotic operation. Early efforts focus on boosting the performance for only one task, \emph{e.g.,} fusion or segmentation, making it hard to…

计算机视觉与模式识别 · 计算机科学 2023-08-07 Jinyuan Liu , Zhu Liu , Guanyao Wu , Long Ma , Risheng Liu , Wei Zhong , Zhongxuan Luo , Xin Fan