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The diagnosis and prognosis of cancer are typically based on multi-modal clinical data, including histology images and genomic data, due to the complex pathogenesis and high heterogeneity. Despite the advancements in digital pathology and…

定量方法 · 定量生物学 2024-04-15 Zeyu Zhang , Yuanshen Zhao , Jingxian Duan , Yaou Liu , Hairong Zheng , Dong Liang , Zhenyu Zhang , Zhi-Cheng Li

Oral cancer is frequently diagnosed at later stages due to its similarity to other lesions. Existing research on computer aided diagnosis has made progress using deep learning; however, most approaches remain limited by small, imbalanced…

计算机视觉与模式识别 · 计算机科学 2026-01-06 Joy Naoum , Revana Salama , Ali Hamdi

Survival prediction is a crucial task in the medical field and is essential for optimizing treatment options and resource allocation. However, current methods often rely on limited data modalities, resulting in suboptimal performance. In…

图像与视频处理 · 电气工程与系统科学 2025-01-07 Binyu Zhang , Zhu Meng , Junhao Dong , Fei Su , Zhicheng Zhao

Molecular subtyping of breast cancer is crucial for personalized treatment and prognosis. Traditional classification approaches rely on either histopathological images or gene expression profiling, limiting their predictive power. In this…

计算机视觉与模式识别 · 计算机科学 2025-03-05 Amin Honarmandi Shandiz

Algorithmic image-based diagnosis and prognosis of neurodegenerative diseases on longitudinal data has drawn great interest from computer vision researchers. The current state-of-the-art models for many image classification tasks are based…

计算机视觉与模式识别 · 计算机科学 2017-09-04 Jie Zhang , Qingyang Li , Richard J. Caselli , Jieping Ye , Yalin Wang

Survival prediction is crucial for cancer patients as it provides early prognostic information for treatment planning. Recently, deep survival models based on deep learning and medical images have shown promising performance for survival…

图像与视频处理 · 电气工程与系统科学 2023-10-03 Mingyuan Meng , Lei Bi , Michael Fulham , Dagan Feng , Jinman Kim

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

Breast cancer is a leading cause of cancer-related mortality worldwide, and timely accurate diagnosis is critical to improving survival outcomes. While convolutional neural networks (CNNs) have demonstrated strong performance on…

计算机视觉与模式识别 · 计算机科学 2026-04-21 Aditya Shribhagwan Khandelwal , Mohammad Samar Ansari , Asra Aslam

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

机器学习 · 计算机科学 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

计算机视觉与模式识别 · 计算机科学 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

Multimodal fusion frameworks, which integrate diverse medical imaging modalities (e.g., MRI, CT), have shown great potential in applications such as skin cancer detection, dementia diagnosis, and brain tumor prediction. However, existing…

计算机视觉与模式识别 · 计算机科学 2026-02-19 J. Dhar , M. K. Pandey , D. Chakladar , M. Haghighat , A. Alavi , S. Mistry , N. Zaidi

Clinical decision-making in oncology involves multimodal data such as radiology scans, molecular profiling, histopathology slides, and clinical factors. Despite the importance of these modalities individually, no deep learning framework to…

计算机视觉与模式识别 · 计算机科学 2021-07-02 Nathaniel Braman , Jacob W. H. Gordon , Emery T. Goossens , Caleb Willis , Martin C. Stumpe , Jagadish Venkataraman

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

定量方法 · 定量生物学 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Accurate prognosis of non-small cell lung cancer (NSCLC) patients undergoing immunotherapy is essential for personalized treatment planning, enabling informed patient decisions, and improving both treatment outcomes and quality of life.…

计算机视觉与模式识别 · 计算机科学 2025-08-22 Qilong Xing , Zikai Song , Bingxin Gong , Lian Yang , Junqing Yu , Wei Yang

Leveraging multimodal information from Magnetic Resonance Imaging (MRI) plays a vital role in lesion segmentation, especially for brain tumors. However, in clinical practice, multimodal MRI data are often incomplete, making it challenging…

计算机视觉与模式识别 · 计算机科学 2026-01-01 Yulong Zou , Bo Liu , Cun-Jing Zheng , Yuan-ming Geng , Siyue Li , Qiankun Zuo , Shuihua Wang , Yudong Zhang , Jin Hong

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

计算机视觉与模式识别 · 计算机科学 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

The Cancer Genome Atlas (TCGA) has enabled novel discoveries and served as a large-scale reference dataset in cancer through its harmonized genomics, clinical, and imaging data. Numerous prior studies have developed bespoke deep learning…

机器学习 · 计算机科学 2026-05-11 Steven Song , Morgan Borjigin-Wang , Irene Madejski , Robert L. Grossman

To improve the prediction of cancer survival using whole-slide images and transcriptomics data, it is crucial to capture both modality-shared and modality-specific information. However, multimodal frameworks often entangle these…

计算机视觉与模式识别 · 计算机科学 2025-06-30 Aniek Eijpe , Soufyan Lakbir , Melis Erdal Cesur , Sara P. Oliveira , Sanne Abeln , Wilson Silva