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Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

其他定量生物学 · 定量生物学 2020-07-13 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

During an epidemic, such as the COVID-19 pandemic, policy-makers are faced with the decision of implementing effective, yet socioeconomically costly intervention strategies, such as school and workplace closure, physical distancing, etc. In…

动力系统 · 数学 2024-07-18 Vasiliki Bitsouni , Nikolaos Gialelis , Vasilis Tsilidis

Epidemic spreading of infectious diseases is ubiquitous and has often considerable impact on public health and economic wealth. The large variability in spatio-temporal patterns of epidemics prohibits simple interventions and demands for a…

种群与进化 · 定量生物学 2010-11-25 Christel Kamp

Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…

Policy responses to COVID-19, particularly those related to non-pharmaceutical interventions, are unprecedented in scale and scope. Epidemiologists are more involved in policy decisions and evidence generation than ever before. However,…

统计方法学 · 统计学 2021-04-20 Noah A Haber , Emma Clarke-Deelder , Joshua A Salomon , Avi Feller , Elizabeth A Stuart

We develop a spatially dependent generalisation to the Wells-Riley model and its extensions applied to COVID-19, that determines the infection risk due to airborne transmission of viruses. We assume that the concentration of infectious…

定量方法 · 定量生物学 2021-05-19 Zechariah Lau , Ian M. Griffiths , Aaron English , Katerina Kaouri

Mathematical modeling has played a central role in understanding how infectious disease transmission manifests in populations. These models have demonstrated the importance of key community-level factors in structuring epidemic risk, and…

A configuration model for epidemic spread, based on a scale-free network, is introduced. We obtain the analytical solutions describing both unstable and stable dynamics of the epidemic spreading, and demonstrate how these regimes can…

物理与社会 · 物理学 2020-07-15 Alexander I Nesterov , Pablo Héctor Mata Villafuerte , Gennady P Berman

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

应用统计 · 统计学 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

During a public health crisis like COVID-19, individuals' adoption of protective behaviors, such as self-isolation and wearing masks, can significantly impact the spread of the disease. In the meanwhile, the spread of the disease can also…

物理与社会 · 物理学 2023-10-27 Wenxiang Dong , H. Vicky Zhao

Much traditional statistical modelling assumes that the outcome variables of interest are independent of each other when conditioned on the explanatory variables. This assumption is strongly violated in the case of infectious diseases,…

种群与进化 · 定量生物学 2019-11-28 Timothy Kinyanjui , Thomas House

This document aims to estimate and describe the effects of the social distancing measures implemented in several countries with the expectancy of controlling the spread of COVID-19. The procedure relies on the classic…

种群与进化 · 定量生物学 2021-06-28 Gerardo L. Febres

Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

种群与进化 · 定量生物学 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

Estimates from infectious disease models have constituted a significant part of the scientific evidence used to inform the response to the COVID-19 pandemic in the UK. These estimates can vary strikingly in their bias and variability.…

应用统计 · 统计学 2022-10-12 R. E. Moore , C. Rosato , S. Maskell

A mathematical model for estimating the risk of airborne transmission of a respiratory infection such as COVID-19, is presented. The model employs basic concepts from fluid dynamics and incorporates the known scope of factors involved in…

种群与进化 · 定量生物学 2020-10-28 Rajat Mittal , Charles Meneveau , Wen Wu

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

社会与信息网络 · 计算机科学 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

During the recent pandemic, a rise in COVID-19 cases was followed by a decline in influenza. In the absence of cross-immunity, a potential explanation for the observed pattern is behavioral: non-pharmaceutical interventions (NPIs) designed…

动力系统 · 数学 2026-04-20 Leah LeJeune , Omar Saucedo , Lauren M. Childs , Navid Ghaffarzadegan

In this paper, a susceptible-infected-removed (SIR) model has been used to track the evolution of the spread of the COVID-19 virus in four countries of interest. In particular, the epidemic model, that depends on some basic characteristics,…

种群与进化 · 定量生物学 2020-10-28 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

During the COVID-19 pandemic of 2019/2020, authorities have used temporary ad-hoc policy measures, such as lockdowns and mass quarantines, to slow its transmission. However, the consequences of widespread use of these unprecedented measures…

The current COVID-19 pandemic and subsequent lockdowns have highlighted the close and delicate relationship between a country's public health and economic health. Macroeconomic models that use preexisting epidemic models to calculate the…

物理与社会 · 物理学 2020-07-01 Erhan Bayraktar , Asaf Cohen , April Nellis