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Mass Spectrometry Imaging (MSI), using traditional rectilinear scanning, takes hours to days for high spatial resolution acquisitions. Given that most pixels within a sample's field of view are often neither relevant to underlying…

图像与视频处理 · 电气工程与系统科学 2022-10-25 David Helminiak , Hang Hu , Julia Laskin , Dong Hye Ye

Spatial Transcriptomics (ST) enables the measurement of gene expression while preserving spatial information, offering critical insights into tissue architecture and disease pathology. Recent developments have explored the use of…

计算机视觉与模式识别 · 计算机科学 2026-05-20 Hai Dang Nguyen , Nguyen Dang Huy Pham , The Minh Duc Nguyen , Dac Thai Nguyen , Hang Thi Nguyen , Duong M. Nguyen

AI-based models for histopathology whole slide image (WSI) analysis are increasingly common, but unsharp or blurred areas within WSI can significantly reduce prediction performance. In this study, we investigated the effect of image blur on…

图像与视频处理 · 电气工程与系统科学 2025-07-21 Yujie Xiang , Bojing Liu , Mattias Rantalainen

Hyperspectral/multispectral imaging (HSI/MSI) contains rich information clinical applications, such as 1) narrow band imaging for vascular visualisation; 2) oxygen saturation for intraoperative perfusion monitoring and clinical decision…

计算机视觉与模式识别 · 计算机科学 2017-07-13 Jianyu Lin , Neil T. Clancy , Daniel S. Elson

Mass spectrometry imaging (MSI) enables label-free visualization of molecular distributions across tissue samples but generates large and complex datasets that require effective peak picking to reduce data size while preserving meaningful…

计算机视觉与模式识别 · 计算机科学 2026-03-12 Philipp Weigand , Nikolas Ebert , Shad A. Mohammed , Denis Abu Sammour , Carsten Hopf , Oliver Wasenmüller

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

定量方法 · 定量生物学 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

We propose SWA-Gaussian (SWAG), a simple, scalable, and general purpose approach for uncertainty representation and calibration in deep learning. Stochastic Weight Averaging (SWA), which computes the first moment of stochastic gradient…

机器学习 · 计算机科学 2020-01-01 Wesley Maddox , Timur Garipov , Pavel Izmailov , Dmitry Vetrov , Andrew Gordon Wilson

We propose a new sampler for robust estimators that always selects the sample with the highest probability of consisting only of inliers. After every unsuccessful iteration, the inlier probabilities are updated in a principled way via a…

计算机视觉与模式识别 · 计算机科学 2023-09-11 Tong Wei , Jiri Matas , Daniel Barath

An efficient, joint transmission delay and channel parameter estimation algorithm is proposed for uplink asynchronous direct-sequence code-division multiple access (DS-CDMA) systems based on the space-alternating generalized expectation…

信息论 · 计算机科学 2016-11-17 E. Panayirci , A. Kocian , H. V. Poor , M. Ruggieri

Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

We consider straggler-resilient learning. In many previous works, e.g., in the coded computing literature, straggling is modeled as random delays that are independent and identically distributed between workers. However, in many practical…

分布式、并行与集群计算 · 计算机科学 2021-11-30 Albin Severinson , Eirik Rosnes , Salim El Rouayheb , Alexandre Graell i Amat

Mammograms are commonly employed in the large scale screening of breast cancer which is primarily characterized by the presence of malignant masses. However, automated image-level detection of malignancy is a challenging task given the…

计算机视觉与模式识别 · 计算机科学 2020-04-27 Sarath Chandra K , Arunava Chakravarty , Nirmalya Ghosh , Tandra Sarkar , Ramanathan Sethuraman , Debdoot Sheet

Cancer survival prediction is a challenging task that involves analyzing of the tumor microenvironment within Whole Slide Image (WSI). Previous methods cannot effectively capture the intricate interaction features among instances within the…

计算机视觉与模式识别 · 计算机科学 2024-10-23 Zekang Yang , Hong Liu , Xiangdong Wang

Whole slide image (WSI) analysis in digital pathology presents unique challenges due to the gigapixel resolution of WSIs and the scarcity of dense supervision signals. While Multiple Instance Learning (MIL) is a natural fit for slide-level…

计算机视觉与模式识别 · 计算机科学 2025-08-21 Sofiène Boutaj , Marin Scalbert , Pierre Marza , Florent Couzinie-Devy , Maria Vakalopoulou , Stergios Christodoulidis

Histopathology image analysis is the golden standard of clinical diagnosis for Cancers. In doctors daily routine and computer-aided diagnosis, the Whole Slide Image (WSI) of histopathology tissue is used for analysis. Because of the…

计算机视觉与模式识别 · 计算机科学 2023-11-23 Honglin Li , Yunlong Zhang , Chenglu Zhu , Jiatong Cai , Sunyi Zheng , Lin Yang

We propose a Hierarchical Multi-scale Knowledge-aware Graph Network (HMKGN) that models multi-scale interactions and spatially hierarchical relationships within whole-slide images (WSIs) for cancer prognostication. Unlike conventional…

图像与视频处理 · 电气工程与系统科学 2026-03-03 Bin Xu , Yufei Zhou , Boling Song , Jingwen Sun , Yang Bian , Cheng Lu , Ye Wu , Jianfei Tu , Xiangxue Wang

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…

图像与视频处理 · 电气工程与系统科学 2021-06-29 Peter Bokor , Lukas Hudec , Ondrej Fabian , Wanda Benesova

Cancer subtyping is one of the most challenging tasks in digital pathology, where Multiple Instance Learning (MIL) by processing gigapixel whole slide images (WSIs) has been in the spotlight of recent research. However, MIL approaches do…

Histopathological images (HIs) are the gold standard for evaluating some types of tumors for cancer diagnosis. The analysis of such images is not only time and resource consuming, but also very challenging even for experienced pathologists,…