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The high-content image-based assay is commonly leveraged for identifying the phenotypic impact of genetic perturbations in biology field. However, a persistent issue remains unsolved during experiments: the interferential technical noise…

图像与视频处理 · 电气工程与系统科学 2022-12-09 Sen Yang , Tao Shen , Yuqi Fang , Xiyue Wang , Jun Zhang , Wei Yang , Junzhou Huang , Xiao Han

The dispute of how the human brain represents conceptual knowledge has been argued in many scientific fields. Brain imaging studies have shown that the spatial patterns of neural activation in the brain are correlated with thinking about…

神经元与认知 · 定量生物学 2018-06-15 Subba Reddy Oota , Naresh Manwani , Bapi Raju S

Neuroimaging studies, such as the Human Connectome Project (HCP), often collect multi-faceted and multi-block data to study the complex human brain. However, these data are often analyzed in a pairwise fashion, which can hinder our…

神经元与认知 · 定量生物学 2024-09-02 Andrew Ackerman , Zhengwu Zhang , Jan Hannig , Jack Prothero , J. S. Marron

Complex functional brain network analyses have exploded over the last eight years, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has…

统计方法学 · 统计学 2013-10-28 Sean L. Simpson , F. DuBois Bowman , Paul J. Laurienti

Recent advances in neuroimaging have deepened our understanding of the brain's complex functional and structural organization. Among these, functional Magnetic Resonance Imaging (fMRI) - particularly resting-state fMRI (rs-fMRI) - has…

计算机视觉与模式识别 · 计算机科学 2026-05-12 M. Moein Esfahani , Sepehr Salem Ghahfarokhi , Mohammed Alser , Jingyu Liu , Vince Calhoun

Neurofibromatosis type 1 (NF1) is an autosomal dominant tumor predisposition syndrome that involves the central and peripheral nervous systems. Accurate detection and segmentation of neurofibromas are essential for assessing tumor burden…

计算机视觉与模式识别 · 计算机科学 2021-06-14 Jian-Wei Zhang , Wei Chen , K. Ina Ly , Xubin Zhang , Fan Yan , Justin Jordan , Gordon Harris , Scott Plotkin , Pengyi Hao , Wenli Cai

In the current paper, we introduce a parametric data-driven model for functional near-infrared spectroscopy that decomposes a signal into a series of independent, rescaled, time-shifted, hemodynamic basis functions. Each decomposed waveform…

信号处理 · 电气工程与系统科学 2020-01-24 Marco A. Pinto-Orellana , Diego C. Nascimento , Peyman Mirtaheri , Rune Jonassen , Anis Yazidi , Hugo L. Hammer

Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that…

机器学习 · 统计学 2019-04-15 Takashi Matsubara , Tetsuo Tashiro , Kuniaki Uehara

Deep neural networks (DNNs) have achieved exceptional performances in many tasks, particularly, in supervised classification tasks. However, achievements with supervised classification tasks are based on large datasets with well-separated…

计算机视觉与模式识别 · 计算机科学 2018-02-06 Kazuma Arino , Yohei Kikuta

Cognition in midlife is an important predictor of age-related mental decline and statistical models that predict cognitive performance can be useful for predicting decline. However, existing models struggle to capture complex relationships…

机器学习 · 计算机科学 2021-12-30 Sharath Koorathota , Arunesh Mittal , Richard P. Sloan , Paul Sajda

Large health surveys increasingly collect high-dimensional functional data from wearable devices, and function on scalar regression (FoSR) is often used to quantify the relationship between these functional outcomes and scalar covariates…

统计方法学 · 统计学 2025-11-10 Lily Koffman , Sunan Gao , Xinkai Zhou , Andrew Leroux , Ciprian Crainiceanu , John Muschelli

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

应用统计 · 统计学 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

In this paper, we provide a comprehensive analysis of periocular-based sex-prediction (commonly referred to as gender classification) using state-of-the-art machine learning techniques. In order to reflect a more challenging scenario where…

计算机视觉与模式识别 · 计算机科学 2019-05-02 Juan Tapia , Christian Rathgeb , Christoph Busch

Academic achievement is a critical measure of intellectual ability, prompting extensive research into cognitive tasks as potential predictors. Neuroimaging technologies, such as functional near-infrared spectroscopy (fNIRS), offer insights…

神经元与认知 · 定量生物学 2024-02-08 Yeaju Kim , Junggu Choi , Bora Kim , Yongwan Park , Jihyun Cha , Jongkwan Choi , Sanghoon Han

We propose a new approach, called as functional deep neural network (FDNN), for classifying multi-dimensional functional data. Specifically, a deep neural network is trained based on the principle components of the training data which shall…

机器学习 · 统计学 2022-05-19 Shuoyang Wang , Guanqun Cao , Zuofeng Shang

Graph neural networks have emerged as a promising approach for the analysis of non-Euclidean data such as meshes. In medical imaging, mesh-like data plays an important role for modelling anatomical structures, and shape classification can…

计算机视觉与模式识别 · 计算机科学 2022-11-01 Nairouz Shehata , Wulfie Bain , Ben Glocker

Functional magnetic resonance imaging (fMRI) has become one of the most common imaging modalities for brain function analysis. Recently, graph neural networks (GNN) have been adopted for fMRI analysis with superior performance.…

神经元与认知 · 定量生物学 2022-11-02 Yue Yu , Xuan Kan , Hejie Cui , Ran Xu , Yujia Zheng , Xiangchen Song , Yanqiao Zhu , Kun Zhang , Razieh Nabi , Ying Guo , Chao Zhang , Carl Yang

This study investigated age-related changes in functional connectivity using resting-state fMRI and explored the efficacy of traditional deep learning for classifying brain developmental stages (BDS). Functional connectivity was assessed…

神经元与认知 · 定量生物学 2025-03-28 Prerna Singh , Kuldeep Singh Yadav , Lalan Kumar , Tapan Kumar Gandhi

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

神经元与认知 · 定量生物学 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Functional subnetwork extraction is commonly used to explore the brain's modular structure. However, reliable subnetwork extraction from functional magnetic resonance imaging (fMRI) data remains challenging due to the pronounced noise in…

神经元与认知 · 定量生物学 2018-01-17 Chendi Wang , Rafeef Abugharbieh