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Detection of cell nuclei in microscopic images is a challenging research topic, because of limitations in cellular image quality and diversity of nuclear morphology, i.e. varying nuclei shapes, sizes, and overlaps between multiple cell…

计算机视觉与模式识别 · 计算机科学 2018-07-10 Mohammad Tofighi , Tiantong Guo , Jairam K. P. Vanamala , Vishal Monga

Designing DNA and protein sequences with improved function has the potential to greatly accelerate synthetic biology. Machine learning models that accurately predict biological fitness from sequence are becoming a powerful tool for…

机器学习 · 计算机科学 2022-03-17 Johannes Linder , Georg Seelig

The deep Convolutional Neural Network (CNN) is the state-of-the-art solution for large-scale visual recognition. Following basic principles such as increasing the depth and constructing highway connections, researchers have manually…

计算机视觉与模式识别 · 计算机科学 2017-03-07 Lingxi Xie , Alan Yuille

Antibiotics are a vital class of drugs closely associated with the prevention and treatment of bacterial infections. Accurate prediction of molecular antimicrobial activity remains a key challenge in the pursuit of novel antibiotic…

定量方法 · 定量生物学 2025-09-23 R. He

Methods for learning Bayesian network structure can discover dependency structure between observed variables, and have been shown to be useful in many applications. However, in domains that involve a large number of variables, the space of…

机器学习 · 计算机科学 2012-12-12 Eran Segal , Dana Pe'er , Aviv Regev , Daphne Koller , Nir Friedman

Protein function prediction is a crucial task in bioinformatics, with significant implications for understanding biological processes and disease mechanisms. While the relationship between sequence and function has been extensively…

定量方法 · 定量生物学 2024-09-04 Shania Mitra , Lei Huang , Manolis Kellis

When we are faced with challenging image classification tasks, we often explain our reasoning by dissecting the image, and pointing out prototypical aspects of one class or another. The mounting evidence for each of the classes helps us…

机器学习 · 计算机科学 2020-01-01 Chaofan Chen , Oscar Li , Chaofan Tao , Alina Jade Barnett , Jonathan Su , Cynthia Rudin

We propose a novel \textit{capsule} based deep encoder-decoder model for surrogate modeling and uncertainty quantification of systems in mechanics from sparse data. The proposed framework is developed by adapting Capsule Network (CapsNet)…

机器学习 · 统计学 2022-01-20 Akshay Thakur , Souvik Chakraborty

Capsule networks are designed to present the objects by a set of parts and their relationships, which provide an insight into the procedure of visual perception. Although recent works have shown the success of capsule networks on simple…

计算机视觉与模式识别 · 计算机科学 2022-03-22 Chang Yu , Xiangyu Zhu , Xiaomei Zhang , Zidu Wang , Zhaoxiang Zhang , Zhen Lei

Capsule Networks (CapsNets) have been re-introduced as a more compact and interpretable alternative to standard deep neural networks. While recent efforts have proved their compression capabilities, to date, their interpretability…

机器学习 · 计算机科学 2024-12-16 Saja Tawalbeh , José Oramas

Capsule neural networks replace simple, scalar-valued neurons with vector-valued capsules. They are motivated by the pattern recognition system in the human brain, where complex objects are decomposed into a hierarchy of simpler object…

计算机视觉与模式识别 · 计算机科学 2023-01-05 Matthias Mitterreiter , Marcel Koch , Joachim Giesen , Sören Laue

In this paper, we present a general and effective framework for Neural Architecture Search (NAS), named PredNAS. The motivation is that given a differentiable performance estimation function, we can directly optimize the architecture…

计算机视觉与模式识别 · 计算机科学 2022-10-27 Liuchun Yuan , Zehao Huang , Naiyan Wang

In this paper, we investigate a new machine learning-based transmission strategy called progressive transmission or ProgTr. In ProgTr, there are b variables that should be transmitted using at most T channel uses. The transmitter aims to…

信号处理 · 电气工程与系统科学 2021-08-18 Mohammad Sadegh Safari , Vahid Pourahmadi , Patrick Mitran , Hamid Sheikhzadeh

The detection of acoustic scenes is a challenging problem in which environmental sound events must be detected from a given audio signal. This includes classifying the events as well as estimating their onset and offset times. We approach…

声音 · 计算机科学 2018-06-14 Turab Iqbal , Yong Xu , Qiuqiang Kong , Wenwu Wang

We propose proximal backpropagation (ProxProp) as a novel algorithm that takes implicit instead of explicit gradient steps to update the network parameters during neural network training. Our algorithm is motivated by the step size…

机器学习 · 计算机科学 2018-02-21 Thomas Frerix , Thomas Möllenhoff , Michael Moeller , Daniel Cremers

Weight space learning aims to extract information about a neural network, such as its training dataset or generalization error. Recent approaches learn directly from model weights, but this presents many challenges as weights are…

机器学习 · 计算机科学 2025-10-23 Jonathan Kahana , Eliahu Horwitz , Imri Shuval , Yedid Hoshen

Biological membranes are one of the most basic structures and regions of interest in cell biology. In the study of membranes, segment extraction is a well-known and difficult problem because of impeding noise, directional and thickness…

计算机视觉与模式识别 · 计算机科学 2018-10-24 Joris Roels , Jonas De Vylder , Jan Aelterman , Yvan Saeys , Wilfried Philips

The folding structure of the DNA molecule combined with helper molecules, also referred to as the chromatin, is highly relevant for the functional properties of DNA. The chromatin structure is largely determined by the underlying primary…

机器学习 · 计算机科学 2018-06-14 Bojian Yin , Marleen Balvert , Davide Zambrano , Alexander Schönhuth , Sander Bohte

Accurately modeling and designing protein complex structures is a central problem in computational structural biology, with broad implications for understanding cellular function and developing therapeutics. This thesis investigates two…

机器学习 · 计算机科学 2026-05-13 Ziwei Xie

Properties of molecules are indicative of their functions and thus are useful in many applications. With the advances of deep learning methods, computational approaches for predicting molecular properties are gaining increasing momentum.…

定量方法 · 定量生物学 2021-07-07 Zhengyang Wang , Meng Liu , Youzhi Luo , Zhao Xu , Yaochen Xie , Limei Wang , Lei Cai , Qi Qi , Zhuoning Yuan , Tianbao Yang , Shuiwang Ji