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The objective of this work was to assess the clinical performance of an unsupervised machine learning model aimed at identifying unusual medication orders and pharmacological profiles. We conducted a prospective study between April 2020 and…

Objective: Patient notes in electronic health records (EHRs) may contain critical information for medical investigations. However, the vast majority of medical investigators can only access de-identified notes, in order to protect the…

计算与语言 · 计算机科学 2016-06-14 Franck Dernoncourt , Ji Young Lee , Ozlem Uzuner , Peter Szolovits

We develop and evaluate a data-driven approach for detecting unusual (anomalous) patient-management actions using past patient cases stored in an electronic health record (EHR) system. Our hypothesis is that patient-management actions that…

机器学习 · 计算机科学 2026-05-07 Milos Hauskrecht , Michal Valko , Shyam Visweswaran , Iyad Batal , Gilles Clermont , Gregory Cooper

Obtaining datasets labeled to facilitate model development is a challenge for most machine learning tasks. The difficulty is heightened for medical imaging, where data itself is limited in accessibility and labeling requires costly time and…

We develop and evaluate a data-driven approach for detecting unusual (anomalous) patient-management decisions using past patient cases stored in electronic health records (EHRs). Our hypothesis is that a patient-management decision that is…

机器学习 · 计算机科学 2026-05-12 Miloš Hauskrecht , Iyad Batal , Michal Valko , Shyam Visweswaran , Gregory F. Cooper , Gilles Clermont

Many computer vision and medical imaging problems are faced with learning from large-scale datasets, with millions of observations and features. In this paper we propose a novel efficient learning scheme that tightens a sparsity constraint…

机器学习 · 统计学 2017-02-07 Adrian Barbu , Yiyuan She , Liangjing Ding , Gary Gramajo

Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes and higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on…

Synthesizing realistic and diverse anomalous samples from limited data is vital for robust model generalization. However, existing methods struggle to reconcile fidelity and diversity, often hampered by distribution misalignment and…

计算机视觉与模式识别 · 计算机科学 2026-05-19 Fuyun Wang , Yuanzhi Wang , Xu Guo , Sujia Huang , Tong Zhang , Dan Wang , Hui Yan , Xin Liu , Zhen Cui

The increasing digitization of medical imaging enables machine learning based improvements in detecting, visualizing and segmenting lesions, easing the workload for medical experts. However, supervised machine learning requires reliable…

图像与视频处理 · 电气工程与系统科学 2024-12-03 Maximilian E. Tschuchnig , Michael Gadermayr

The concept of personalised medicine in cancer therapy is becoming increasingly important. There already exist drugs administered specifically for patients with tumours presenting well-defined mutations. However, the field is still in its…

生物大分子 · 定量生物学 2024-08-26 Abbi Abdel-Rehim , Oghenejokpeme Orhobor , Gareth Griffiths , Larisa Soldatova , Ross D. King

We develop graph-based methods for semi-supervised learning based on label propagation on a data similarity graph. When data is abundant or arrive in a stream, the problems of computation and data storage arise for any graph-based method.…

机器学习 · 计算机科学 2026-05-06 Michal Valko

We consider the problem of identifying patterns in a data set that exhibit anomalous behavior, often referred to as anomaly detection. Similarity-based anomaly detection algorithms detect abnormally large amounts of similarity or…

计算机视觉与模式识别 · 计算机科学 2016-07-26 Ko-Jen Hsiao , Kevin S. Xu , Jeff Calder , Alfred O. Hero

We consider the problem of identifying patterns in a data set that exhibit anomalous behavior, often referred to as anomaly detection. In most anomaly detection algorithms, the dissimilarity between data samples is calculated by a single…

机器学习 · 计算机科学 2013-01-08 Ko-Jen Hsiao , Kevin S. Xu , Jeff Calder , Alfred O. Hero

Machine learning (ML) algorithms are optimized for the distribution represented by the training data. For outlier data, they often deliver predictions with equal confidence, even though these should not be trusted. In order to deploy…

图像与视频处理 · 电气工程与系统科学 2021-03-17 Milda Pocevičiūtė , Gabriel Eilertsen , Claes Lundström

Recommending safe and effective medication combinations from electronic health records (EHRs) is a core clinical AI problem, yet it remains difficult because patient trajectories are long, noisy, and clinically heterogeneous. Existing…

机器学习 · 计算机科学 2026-05-21 Krati Saxena , Tomohiro Shibata

Checklists are simple decision aids that are often used to promote safety and reliability in clinical applications. In this paper, we present a method to learn checklists for clinical decision support. We represent predictive checklists as…

机器学习 · 计算机科学 2022-01-19 Haoran Zhang , Quaid Morris , Berk Ustun , Marzyeh Ghassemi

Photoplethysmography (PPG) signals, typically acquired from wearable devices, hold significant potential for continuous fitness-health monitoring. In particular, heart conditions that manifest in rare and subtle deviating heart patterns may…

机器学习 · 计算机科学 2023-07-14 Ramin Ghorbani , Marcel J. T. Reinders , David M. J. Tax

This paper studies the problem of detecting anomalous graphs using a machine learning model trained on only normal graphs, which has many applications in molecule, biology, and social network data analysis. We present a self-discriminative…

机器学习 · 计算机科学 2023-10-11 Jinyu Cai , Yunhe Zhang , Jicong Fan

Internet data has surfaced as a primary source for investigation of different aspects of human behavior. A crucial step in such studies is finding a suitable cohort (i.e., a set of users) that shares a common trait of interest to…

信息检索 · 计算机科学 2018-05-16 Luca Soldaini , Elad Yom-Tov

This study investigates the adoption and effectiveness of AI-based anomaly detection in cross-provider electronic health record (EHR) environments. It aims to (1) identify the organisational and digital capabilities required for successful…

计算机与社会 · 计算机科学 2026-04-14 Cao Tram Anh Hoang