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The predictive accuracy of Machine Learning (ML) models of molecular properties depends on the choice of the molecular representation. Based on the postulates of quantum mechanics, we introduce a hierarchy of representations which meet…

化学物理 · 物理学 2016-11-23 Bing Huang , O. Anatole von Lilienfeld

Graph rewrite formalisms are a powerful approach to modeling complex molecular systems. They capture the intrinsic concurrency of molecular interactions, thereby enabling a formal notion of mechanism (a partially ordered set of events) that…

计算机科学中的逻辑 · 计算机科学 2019-01-04 Ioana Cristescu , Walter Fontana , Jean Krivine

Graphs are ubiquitous data structures for representing interactions between entities. With an emphasis on the use of graphs to represent chemical molecules, we explore the task of learning to generate graphs that conform to a distribution…

机器学习 · 计算机科学 2019-03-08 Qi Liu , Miltiadis Allamanis , Marc Brockschmidt , Alexander L. Gaunt

Autocatalytic sets are sets of entities that mutually catalyse each other's production through chemical reactions from a basic food source. Recently, the reflexively autocatalytic and food generated theory has introduced a formal definition…

适应与自组织系统 · 物理学 2020-09-15 Alessandro Ravoni

Cellular automata have been useful artificial models for exploring how relatively simple rules combined with spatial memory can give rise to complex emergent patterns. Moreover, studying the dynamics of how rules emerge under artificial…

元胞自动机与格子气 · 物理学 2014-07-11 Theodore P. Pavlic , Alyssa M. Adams , Paul C. W. Davies , Sara Imari Walker

The current work addresses a virtual environment with self-replicating agents whose decisions are based on a form of "somatic computation" (soma - body) in which basic emotional responses, taken in parallelism to actual living organisms,…

人工智能 · 计算机科学 2014-01-10 Carlos Pedro Gonçalves

Gene Regulatory Networks are networks of interactions in biological organisms responsible for determining the production levels of proteins and peptides. Proteins are workers of a cell factory, and their production defines the goal of a…

神经与进化计算 · 计算机科学 2022-09-12 Iliya Miralavy , Wolfgang Banzhaf

Many cellular and subcellular biological processes can be described in terms of diffusing and chemically reacting species (e.g. enzymes). Such reaction-diffusion processes can be mathematically modelled using either deterministic…

生物物理 · 物理学 2015-06-26 Radek Erban , S. Jonathan Chapman

This study aims at finding a method for constructing molecular dynamics like models using the formalism of cellular automata for fast simulation of fluid dynamic systems (including compressible phenomena). In as much as the results…

comp-gas · 物理学 2009-09-25 Himanshu Agrawal

Formation of a molecular network from multifunctional precursors is modelled with a random graph process. The random graph model favours reactivity for monomers that are positioned close in the network topology, and disfavours reactivity…

软凝聚态物质 · 物理学 2019-08-21 Ivan Kryven , Jorien Duivenvoorden , Joen Hermans , Piet D. Iedema

Processes involving multi-input multi-step reaction cascades are used in developing novel biosensing, biocomputing, and decision making systems. In various applications different changes in responses of the constituent processing steps…

分子网络 · 定量生物学 2016-08-16 Sergii Domanskyi , Vladimir Privman

With the rise of service-oriented computing, applications are more and more based on coordination of autonomous services. Envisioned over largely distributed and highly dynamic platforms, expressing this coordination calls for alternative…

分布式、并行与集群计算 · 计算机科学 2012-03-15 Marin Bertier , Marko Obrovac , Cédric Tedeschi

Situationally-aware artificial agents operating with competence in natural environments face several challenges: spatial awareness, object affordance detection, dynamic changes and unpredictability. A critical challenge is the agent's…

机器人学 · 计算机科学 2025-07-29 Mihai Pomarlan , Stefano De Giorgis , Rachel Ringe , Maria M. Hedblom , Nikolaos Tsiogkas

The vast majority of visual animals actively control their eyes, heads, and/or bodies to direct their gaze toward different parts of their environment. In contrast, recent applications of reinforcement learning in robotic manipulation…

计算机视觉与模式识别 · 计算机科学 2020-03-17 Youssef Zaky , Gaurav Paruthi , Bryan Tripp , James Bergstra

Reaction networks are widely used models to describe biochemical processes. Stochastic fluctuations in the counts of biological macromolecules have amplified consequences due to their small population sizes. This makes it necessary to favor…

概率论 · 数学 2022-02-28 Daniele Cappelletti , Badal Joshi

Designing molecules with specific properties is a long-lasting research problem and is central to advancing crucial domains such as drug discovery and material science. Recent advances in deep graph generative models treat molecule design…

机器学习 · 计算机科学 2022-03-02 Yuanqi Du , Xiaojie Guo , Amarda Shehu , Liang Zhao

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

分子网络 · 定量生物学 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

We present a 2-dimensional cellular automaton model for the simulation of pedestrian dynamics. The model is extremely efficient and allows simulations of large crowds faster than real time since it includes only nearest-neighbour…

统计力学 · 物理学 2007-05-23 Andreas Schadschneider

The applications of machine learning techniques to chemistry and materials science become more numerous by the day. The main challenge is to devise representations of atomic systems that are at the same time complete and concise, so as to…

化学物理 · 物理学 2025-10-06 Michael J. Willatt , Felix Musil , Michele Ceriotti

A universal feature of the biochemistry of any living system is that all the molecules and catalysts that are required for reactions of the system can be built up from an available food source by repeated application of reactions from…

分子网络 · 定量生物学 2013-07-11 Wim Hordijk , Peter R. Wills , Mike Steel
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