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相关论文: Explainable Biomedical Recommendations via Reinfor…

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Biomedical knowledge graphs permit an integrative computational approach to reasoning about biological systems. The nature of biological data leads to a graph structure that differs from those typically encountered in benchmarking datasets.…

机器学习 · 计算机科学 2021-03-19 Yushan Liu , Marcel Hildebrandt , Mitchell Joblin , Martin Ringsquandl , Rime Raissouni , Volker Tresp

The graph structure of biomedical data differs from those in typical knowledge graph benchmark tasks. A particular property of biomedical data is the presence of long-range dependencies, which can be captured by patterns described as…

机器学习 · 计算机科学 2020-07-13 Yushan Liu , Marcel Hildebrandt , Mitchell Joblin , Martin Ringsquandl , Volker Tresp

Recent work on recommender systems has considered external knowledge graphs as valuable sources of information, not only to produce better recommendations but also to provide explanations of why the recommended items were chosen. Pure…

信息检索 · 计算机科学 2020-07-28 Yikun Xian , Zuohui Fu , Qiaoying Huang , S. Muthukrishnan , Yongfeng Zhang

Recent advances in personalized recommendation have sparked great interest in the exploitation of rich structured information provided by knowledge graphs. Unlike most existing approaches that only focus on leveraging knowledge graphs for…

信息检索 · 计算机科学 2019-06-13 Yikun Xian , Zuohui Fu , S. Muthukrishnan , Gerard de Melo , Yongfeng Zhang

Discovering new medicines is the hallmark of human endeavor to live a better and longer life. Yet the pace of discovery has slowed down as we need to venture into more wildly unexplored biomedical space to find one that matches today's high…

人工智能 · 计算机科学 2022-02-16 Tri Minh Nguyen , Thin Nguyen , Truyen Tran

Neurosymbolic AI is an increasingly active area of research that combines symbolic reasoning methods with deep learning to leverage their complementary benefits. As knowledge graphs are becoming a popular way to represent heterogeneous and…

人工智能 · 计算机科学 2025-01-13 Lauren Nicole DeLong , Ramon Fernández Mir , Jacques D. Fleuriot

Knowledge graph reasoning is the fundamental component to support machine learning applications such as information extraction, information retrieval, and recommendation. Since knowledge graphs can be viewed as the discrete symbolic…

人工智能 · 计算机科学 2021-04-01 Jing Zhang , Bo Chen , Lingxi Zhang , Xirui Ke , Haipeng Ding

Knowledge graphs are powerful tools for representing and organising complex biomedical data. Several knowledge graph embedding algorithms have been proposed to learn from and complete knowledge graphs. However, a recent study demonstrates…

Biomedical datasets are often modeled as knowledge graphs (KGs) because they capture the multi-relational, heterogeneous, and dynamic natures of biomedical systems. KG completion (KGC), can, therefore, help researchers make predictions to…

Knowledge graphs (KGs) are powerful tools for modelling complex, multi-relational data and supporting hypothesis generation, particularly in applications like drug repurposing. However, for predictive methods to gain acceptance as credible…

人工智能 · 计算机科学 2026-02-06 Susana Nunes , Samy Badreddine , Catia Pesquita

There has been growing attention on fairness considerations recently, especially in the context of intelligent decision making systems. Explainable recommendation systems, in particular, may suffer from both explanation bias and performance…

Motivation: Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. In the past years, feature learning methods that are…

Medical diagnosis is the process of making a prediction of the disease a patient is likely to have, given a set of symptoms and observations. This requires extensive expert knowledge, in particular when covering a large variety of diseases.…

人工智能 · 计算机科学 2022-04-29 Niclas Heilig , Jan Kirchhoff , Florian Stumpe , Joan Plepi , Lucie Flek , Heiko Paulheim

Neurosymbolic artificial intelligence is a growing field of research aiming to combine neural network learning capabilities with the reasoning abilities of symbolic systems. Informed multi-label classification is a sub-field of…

人工智能 · 计算机科学 2025-01-24 Arthur Ledaguenel , Céline Hudelot , Mostepha Khouadjia

Recommender Systems have been widely used to help users in finding what they are looking for thus tackling the information overload problem. After several years of research and industrial findings looking after better algorithms to improve…

信息检索 · 计算机科学 2018-07-18 Vito Bellini , Angelo Schiavone , Tommaso Di Noia , Azzurra Ragone , Eugenio Di Sciascio

Recent years have witnessed a rapid growth of recommender systems, providing suggestions in numerous applications with potentially high social impact, such as health or justice. Meanwhile, in Europe, the upcoming AI Act mentions…

人工智能 · 计算机科学 2024-07-18 Simon Delarue , Astrid Bertrand , Tiphaine Viard

Large language models have achieved near-expert performance in structured reasoning domains like mathematics and programming, yet their ability to perform compositional multi-hop reasoning in specialized scientific fields remains limited.…

人工智能 · 计算机科学 2026-03-09 Yuval Kansal , Niraj K. Jha

We introduced a methodology to efficiently exploit natural-language expressed biomedical knowledge for repurposing existing drugs towards diseases for which they were not initially intended. Leveraging on developments in Computational…

定量方法 · 定量生物学 2014-06-17 Ruggero Gramatica , T. Di Matteo , Stefano Giorgetti , Massimo Barbiani , Dorian Bevec , Tomaso Aste

Drug repurposing is more relevant than ever due to drug development's rising costs and the need to respond to emerging diseases quickly. Knowledge graph embedding enables drug repurposing using heterogeneous data sources combined with…

Clinical evidence encompasses the associations and impacts between patients, interventions (such as drugs or physiotherapy), problems, and outcomes. The goal of recommending clinical evidence is to provide medical practitioners with…

计算与语言 · 计算机科学 2023-04-05 Maolin Luo , Xiang Zhang
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