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This study proposes a novel approach combining Multimodal Deep Learning with intrinsic eXplainable Artificial Intelligence techniques to predict pathological response in non-small cell lung cancer patients undergoing neoadjuvant therapy.…

Deep learning (DL) models have achieved paradigm-changing performance in many fields with high dimensional data, such as images, audio, and text. However, the black-box nature of deep neural networks is a barrier not just to adoption in…

机器学习 · 计算机科学 2020-02-25 Parmita Mehta , Stephen Portillo , Magdalena Balazinska , Andrew Connolly

Accurate identification of nonlinear material parameters from three-dimensional full-field deformation data remains a challenge in experimental mechanics. The virtual fields method (VFM) provides a powerful, computationally efficient…

软凝聚态物质 · 物理学 2026-01-21 Denislav P. Nikolov , Zhiren Zhu , Jonathan B. Estrada

The seemingly simple process of inhalation relies on a complex interplay between muscular contraction in the thorax, elasto-capillary interactions in individual lung branches, propagation of air between different connected branches, and…

生物物理 · 物理学 2022-06-07 Jean-François Louf , Felix Kratz , Sujit S. Datta

Unraveling the connections between microscopic structure, emergent physical properties, and slow dynamics has long been a challenge when studying the glass transition. The absence of clear visible structural order in amorphous…

Pathology reports are structured, multi-granular documents encoding diagnostic conclusions, histological grades, and ancillary test results across one or more anatomical sites; yet existing pathology vision-language models (VLMs) reduce…

计算机视觉与模式识别 · 计算机科学 2026-03-23 Ruicheng Yuan , Zhenxuan Zhang , Anbang Wang , Liwei Hu , Xiangqian Hua , Yaya Peng , Jiawei Luo , Guang Yang

Accurately modeling the structural reconstruction and thermodynamic behavior of van der Waals (vdW) heterostructures remains a significant challenge due to the limitations of conventional force fields in capturing their complex mechanical,…

计算物理 · 物理学 2026-02-26 Hekai Bu , Wenwu Jiang , Penghua Ying , Ting Liang , Zheyong Fan , Wengen Ouyang

Safe autonomous systems in complex environments require robust road anomaly segmentation to identify unknown obstacles. However, existing approaches often rely on pixel-level statistics to determine whether a region appears anomalous. This…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Zhuolin He , Jiacheng Tang , Jian Pu , Xiangyang Xue

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Ordinary differential equations (ODEs) can provide mechanistic models of temporally local changes of processes, where parameters are often informed by external knowledge. While ODEs are popular in systems modeling, they are less established…

统计方法学 · 统计学 2025-07-10 Maren Hackenberg , Astrid Pechmann , Clemens Kreutz , Janbernd Kirschner , Harald Binder

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

计算机视觉与模式识别 · 计算机科学 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

A particular type of assistive robots designed for physical interaction with objects could play an important role assisting with mobility and fall prevention in healthcare facilities. Autonomous mobile manipulation presents a hurdle prior…

机器人学 · 计算机科学 2020-11-12 Roya Sabbagh Novin , Amir Yazdani , Andrew Merryweather , Tucker Hermans

Interstitial lung diseases are a large group of heterogeneous diseases characterized by different degrees of alveolitis and pulmonary fibrosis. Accurately diagnosing these diseases has significant guiding value for formulating treatment…

图像与视频处理 · 电气工程与系统科学 2022-06-22 Huafeng Hu , Ruijie Ye , Jeyarajan Thiyagalingam , Frans Coenen , Jionglong Su

Visual grounding (VG) is the capability to identify the specific regions in an image associated with a particular text description. In medical imaging, VG enhances interpretability by highlighting relevant pathological features…

Multimodal large models have shown great potential in automating pathology image analysis. However, current multimodal models for gastrointestinal pathology are constrained by both data quality and reasoning transparency: pervasive noise…

图像与视频处理 · 电气工程与系统科学 2025-07-25 Minxi Ouyang , Lianghui Zhu , Yaqing Bao , Qiang Huang , Jingli Ouyang , Tian Guan , Xitong Ling , Jiawen Li , Song Duan , Wenbin Dai , Li Zheng , Xuemei Zhang , Yonghong He

Obesity is a common issue in modern societies today that can lead to various diseases and significantly reduced quality of life. Currently, research has been conducted to investigate resting state EEG (electroencephalogram) signals with an…

机器学习 · 计算机科学 2023-02-03 Yuan Yue , Jeremiah D. Deng , Dirk De Ridder , Patrick Manning , Divya Adhia

Pneumothorax, a life threatening disease, needs to be diagnosed immediately and efficiently. The prognosis in this case is not only time consuming but also prone to human errors. So an automatic way of accurate diagnosis using chest X-rays…

计算机视觉与模式识别 · 计算机科学 2020-12-23 Tahira Iqbal , Arslan Shaukat , Usman Akram , Zartasha Mustansar , Yung-Cheol Byun

Given Spatial Variability Aware Neural Networks (SVANNs), the goal is to investigate mathematical (or computational) models for comparative physical interpretation towards their transparency (e.g., simulatibility, decomposability and…

机器学习 · 计算机科学 2021-11-01 Jayant Gupta , Carl Molnar , Gaoxiang Luo , Joe Knight , Shashi Shekhar

Topology is critical in tubular structures such as blood vessels, nerve fibers, and road networks, where connectivity and loop structure govern downstream functional analysis. Vision-Language Models (VLMs) are promising candidates for…

计算机视觉与模式识别 · 计算机科学 2026-05-14 Meilong Xu , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Xin Yu , Weimin Lyu , Kehan Qi , Dimitris Samaras , Chao Chen

Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

图像与视频处理 · 电气工程与系统科学 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang