相关论文: Finite-element modeling of the alpha particle dose…
Diffusing alpha-emitters radiation therapy (Alpha-DaRT) is a new modality that uses alpha particles to treat solid tumors. Alpha-DaRT employs interstitial sources loaded with low activities of Radium-224, which release a chain of…
Diffusing alpha-emitters Radiation Therapy (Alpha DaRT) enables the use of alpha particles for the treatment of solid tumors. It employs interstitial sources carrying a few uCi of Ra-224, designed to release its short-lived progeny, which…
Diffusing alpha-emitters Radiation Therapy ("Alpha DaRT") is a new treatment modality focusing on the use of alpha particles against solid tumors. The introduction of Alpha DaRT in clinical settings calls for the development of detailed…
Alpha-DaRT is a new method for treating solid tumors with alpha particles, relying on the release of the alpha-emitting daughter atoms of radium-224 from sources inserted into the tumor. The most important model parameters for Alpha-DaRT…
Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…
Thermal Radiative Transfer (TRT) is the dominant energy transfer mechanism in high-energy density physics with applications in inertial confinement fusion and astrophysics. The stiff interactions between the material and radiation fields…
Diffuse scattering is a rich source of information about disorder in crystalline materials, which can be modelled using atomistic techniques such as Monte Carlo and molecular dynamics simulations. Modern X-ray and neutron scattering…
We develop a linear fully discrete structure-preserving finite element method for a diffuse-interface model of tumour growth. The system couples a Cahn--Hilliard type equation with a nonlinear reaction-diffusion equation for nutrient…
Near infrared diffuse optical tomography (DOT) provides an imaging modality for the oxygenation of tissue. In this paper, we propose a novel machine learning algorithm based on time-domain radiative transfer equation. We use temporal…
We study the scattering of two-level atoms at narrow laser fields, modeled by a $\delta$-shape intensity profile. The unique properties of these potentials allow us to give simple analytic solutions for one or two field zones. Several…
While spatial dose conformity delivered to a target volume has been pushed to its practical limits with advanced treatment planning and delivery, investigations in novel temporal dose delivery are unfolding new mechanisms. Recent advances…
We used Monte Carlo simulations to study release of radium-224 daughter nuclei from the seed used for Diffusing Alpha-Emitters Radiation Therapy (DART). Calculated desorption probabilities for polonium-216 (15%) and lead-212 (12%) show that…
Radiation therapy aims to deliver the prescribed amount of dose to a tumour at the same time as sparing the surrounding tissues as much as possible. In charged particle therapy, delivering the prescribed dose is equivalent to delivering the…
In this paper, we propose a novel adaptive finite element method for an elliptic equation with line Dirac delta functions as a source term. We first study the well-posedness and global regularity of the solution in the whole domain. Instead…
The discrete-dipole approximation (DDA) is a powerful method for calculating absorption and scattering by targets that have sizes smaller than or comparable to the wavelength of the incident radiation. The DDA can be extended to targets…
The diffusion limited aggregation model (DLA) and the more general dielectric breakdown model (DBM) are solved exactly in a two dimensional cylindrical geometry with periodic boundary conditions of width 2. Our approach follows the exact…
An operator-splitting finite element scheme for the time-dependent, high-dimensional radiative transfer equation is presented in this paper. The streamline upwind Petrov-Galerkin finite element method and discontinuous Galerkin finite…
We conduct a theoretical study of various solution methods for the adaptive fractionation problem. The two messages of this paper are: (i) dynamic programming (DP) is a useful framework for adaptive radiation therapy, particularly adaptive…
A finite element method for solving the resonance line transfer problem in moving media is presented. The algorithm works in three spatial dimensions on unstructured grids which are adaptively refined by means of an a posteriori error…
The present paper deals with the study of the fluence rate over both healthy and tumor tissues in the presence of focal laser ablation (FLA). We propose new analytical solutions for the coupled partial differential equations (PDE) system,…