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相关论文: Light-Field Microscopy for optical imaging of neur…

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Mean-field models provide a link between microscopic neuronal activity and macroscopic brain dynamics. Their derivation depends on simplifying assumptions, such as all-to-all connectivity, limiting their biological realism. To overcome…

神经元与认知 · 定量生物学 2025-09-05 Martin Breyton , Viktor Sip , Marmaduke Woodman , Meysam Hashemi , Spase Petkoski , Viktor Jirsa

Fourier Ptychographic Microscopy (FPM) is a computational technique that achieves a large space-bandwidth product imaging. It addresses the challenge of balancing a large field of view and high resolution by fusing information from multiple…

光学 · 物理学 2023-04-21 Ruiqing Sun , Delong Yang , Yao Hu , Qun Hao , Xin Li , Shaohui Zhang

Inferring representations of 3D scenes from 2D observations is a fundamental problem of computer graphics, computer vision, and artificial intelligence. Emerging 3D-structured neural scene representations are a promising approach to 3D…

计算机视觉与模式识别 · 计算机科学 2022-01-19 Vincent Sitzmann , Semon Rezchikov , William T. Freeman , Joshua B. Tenenbaum , Fredo Durand

A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

生物物理 · 物理学 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

We developed a Bessel light sheet fluorescence microscopy (LSFM) system to enable high-speed, wide-field intra-vital imaging of zebrafish and other thick biological samples. This system uses air objectives for the convenient mounting of…

光学 · 物理学 2023-11-07 Chuhui Wang , Jiaju Chen , Cuiyi Peng , Zhenglin Chen , Dongmei Yu , Peiwu Qin

Real-time 3D fluorescence microscopy is crucial for the spatiotemporal analysis of live organisms, such as neural activity monitoring. The eXtended field-of-view light field microscope (XLFM), also known as Fourier light field microscope,…

图像与视频处理 · 电气工程与系统科学 2023-06-16 Josué Page Vizcaíno , Panagiotis Symvoulidis , Zeguan Wang , Jonas Jelten , Paolo Favaro , Edward S. Boyden , Tobias Lasser

Atomic force microscopy (AFM or SPM) imaging is one of the best matches with machine learning (ML) analysis among microscopy techniques. The digital format of AFM images allows for direct utilization in ML algorithms without the need for…

生物物理 · 物理学 2025-01-07 Igor Sokolov

Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

图像与视频处理 · 电气工程与系统科学 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

Optical microscopy is an indispensable tool in life sciences research, but conventional techniques require compromises between imaging parameters like speed, resolution, field-of-view, and phototoxicity. To overcome these limitations,…

定量方法 · 定量生物学 2024-04-01 Leonor Morgado , Estibaliz Gómez-de-Mariscal , Hannah S. Heil , Ricardo Henriques

Ultrafast 3D imaging is indispensable for visualizing complex and dynamic biological processes. Conventional scanning-based techniques necessitate an inherent trade-off between acquisition speed and space-bandwidth product (SBP). Emerging…

Light sheet fluorescence microscopy (LSFM) has transformed the way we visualize biological tissues in three dimensions, offering high-resolution imaging while minimizing photo-induced damage to the samples. Recent breakthroughs in…

光学 · 物理学 2025-05-27 Alireza Tabatabaei Mashayekh , Jeremy Witzens

In recent years, visual sensors have been quickly improving, notably targeting richer acquisitions of the light present in a visual scene. In this context, the so-called lenslet light field (LLF) cameras are able to go beyond the…

图像与视频处理 · 电气工程与系统科学 2020-03-06 Catarina Brites , João Ascenso , Fernando Pereira

The glow of a starry night sky, the smell of a freshly brewed cup of coffee or the sound of ocean waves breaking on the beach are representations of the physical world that have been created by the dynamic interactions of thousands of…

神经元与认知 · 定量生物学 2011-07-28 Henry Lütcke , Fritjof Helmchen

Light field microscopy (LFM) has gained significant attention due to its ability to capture snapshot-based, large-scale 3D fluorescence images. However, existing LFM reconstruction algorithms are highly sensitive to sensor noise or require…

计算机视觉与模式识别 · 计算机科学 2026-05-27 Jiayin Zhao , Zhenqi Fu , Tao Yu , Hui Qiao

Light-sheet fluorescence microscopy (LSFM) enables real-time whole-brain functional imaging in zebrafish larvae. Conventional one photon LSFM can however induce undesirable visual stimulation due to the use of visible excitation light. The…

High-speed optical imaging of dynamic neuronal activity is essential yet challenging in neuroscience. While calcium imaging has been firmly established as a workhorse technique for monitoring neuronal activity, its limited temporal…

The convergence of recent advances in optical fabrication and digital processing yields a new generation of imaging technology: light-field cameras, which bridge the realms of applied mathematics, optics, and high-performance computing.…

图像与视频处理 · 电气工程与系统科学 2018-01-25 Shuaishuai Zhu , Peng Jin , Rongguang Liang , Liang Gao

Due to rapid advances in multielectrode recording technology, the local field potential (LFP) has again become a popular measure of neuronal activity in both basic research and clinical applications. Proper understanding of the LFP requires…

Large Language Models have achieved remarkable success in language understanding and reasoning, and their multimodal extensions enable comprehension of images, video, and audio. Inspired by this, foundation models for brain functional…

人工智能 · 计算机科学 2026-03-03 Xingcan Hu , Wei Wang , Li Xiao

Light Field (LF) offers unique advantages such as post-capture refocusing and depth estimation, but low-light conditions limit these capabilities. To restore low-light LFs we should harness the geometric cues present in different LF views,…

图像与视频处理 · 电气工程与系统科学 2020-12-29 Mohit Lamba , Kranthi Kumar , Kaushik Mitra