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When estimating an effect of an action with a randomized or observational study, that study is often not a random sample of the desired target population. Instead, estimates from that study can be transported to the target population.…

Bipartite experiments arise in various fields, in which the treatments are randomized over one set of units, while the outcomes are measured over another separate set of units. However, existing methods often rely on strong model…

统计方法学 · 统计学 2025-04-16 Sizhu Lu , Lei Shi , Yue Fang , Wenxin Zhang , Peng Ding

Spurious association arises from covariance between propensity for the treatment and individual risk for the outcome. For sensitivity analysis with stochastic counterfactuals we introduce a methodology to characterize uncertainty in causal…

统计方法学 · 统计学 2021-03-11 Brian Knaeble , Braxton Osting , Placede Tshiaba

Causal evidence is needed to act and it is often enough for the evidence to point towards a direction of the effect of an action. For example, policymakers might be interested in estimating the effect of slightly increasing taxes on private…

统计方法学 · 统计学 2020-08-11 Dominik Rothenhäusler , Bin Yu

In causal inference, it is common to estimate the causal effect of a single treatment variable on an outcome. However, practitioners may also be interested in the effect of simultaneous interventions on multiple covariates of a fixed target…

统计方法学 · 统计学 2022-11-24 Jaime Roquero Gimenez , Dominik Rothenhäusler

Recent work has focused on the potential and pitfalls of causal identification in observational studies with multiple simultaneous treatments. Building on previous work, we show that even if the conditional distribution of unmeasured…

统计方法学 · 统计学 2025-03-28 Jiajing Zheng , Alexander D'Amour , Alexander Franks

Though the topic of causal inference is typically considered in the context of classical statistical models, recent years have seen great interest in extending causal inference techniques to quantum and generalized theories. Causal…

计算机科学中的逻辑 · 计算机科学 2023-11-16 Isaac Friend , Aleks Kissinger

Standard causal inference characterizes treatment effect through averages, but the counterfactual distributions could be different in not only the central tendency but also spread and shape. To provide a comprehensive evaluation of…

统计方法学 · 统计学 2022-11-04 Steven G. Xu , Shu Yang , Brian J. Reich

Epidemiologists and applied statisticians often believe that relative effect measures conditional on covariates, such as risk ratios and mean ratios, are ``transportable'' across populations. Here, we examine the identification of causal…

统计方法学 · 统计学 2022-02-24 Issa J. Dahabreh , Sarah E. Robertson , Jon A. Steingrimsson

Unmeasured confounding presents a significant challenge in causal inference from observational studies. Classical approaches often rely on collecting proxy variables, such as instrumental variables. However, in applications where the…

统计方法学 · 统计学 2025-01-16 Xiaochuan Shi , Dehan Kong , Linbo Wang

Recently, there has been great interest in estimating the conditional average treatment effect using flexible machine learning methods. However, in practice, investigators often have working hypotheses about effect heterogeneity across…

统计方法学 · 统计学 2023-09-13 Chan Park , Hyunseung Kang

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated…

统计方法学 · 统计学 2026-04-06 Jianan Zhu , Jeffrey Zhang , Zijian Guo , Siyu Heng

We introduce causal inference reasoning to cross-over trials, with a focus on Thorough QT (TQT) studies. For such trials, we propose different sets of assumptions and consider their impact on the modelling strategy and estimation procedure.…

统计方法学 · 统计学 2022-05-31 Jeppe Ekstrand Halkjær Madsen , Thomas Scheike , Christian Pipper

Estimating causal effects in a target population with unmeasured confounders is challenging, especially when instrumental variables (IVs) are unavailable. However, IVs from auxiliary populations with similar problems can help infer causal…

统计方法学 · 统计学 2025-08-06 Wei Li , Jiapeng Liu , Peng Ding , Zhi Geng

Over the past two decades, considerable strides have been made in advancing neuroscientific techniques, yet challenges remain in attributing causality to observed associations. This review addresses a fundamental issue in observational…

其他定量生物学 · 定量生物学 2025-11-04 Eric W. Bridgeford , Brian S. Caffo , Maya B. Mathur , Russell A. Poldrack

When domain knowledge is limited and experimentation is restricted by ethical, financial, or time constraints, practitioners turn to observational causal discovery methods to recover the causal structure, exploiting the statistical…

The estimation of causal treatment effects from observational data is a fundamental problem in causal inference. To avoid bias, the effect estimator must control for all confounders. Hence practitioners often collect data for as many…

机器学习 · 统计学 2020-11-05 Kristjan Greenewald , Dmitriy Katz-Rogozhnikov , Karthik Shanmugam

We extend Fisher's randomization test (FRT) to test conditional independence between observed outcomes and treatments given covariates in both randomized experiments and observational studies, with no restriction on the variable type of…

统计方法学 · 统计学 2025-06-12 Zhen Zhong

For the purpose of causal inference we employ a stochastic model of the data generating process, utilizing individual propensity probabilities for the treatment, and also individual and counterfactual prognosis probabilities for the…

统计方法学 · 统计学 2024-07-15 Brian Knaeble , Mehdi Hakim-Hashemi , Mark A. Abramson

In prior work we have introduced an asymptotic threshold of sufficient randomness for causal inference from observational data. In this paper we extend that prior work in three main ways. First, we show how to empirically estimate a lower…

统计方法学 · 统计学 2023-09-07 Brian Knaeble , Braxton Osting , Placede Tshiaba