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Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

人工智能 · 计算机科学 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

Monitoring key elements of disease dynamics (e.g., prevalence, case counts) is of great importance in infectious disease prevention and control, as emphasized during the COVID-19 pandemic. To facilitate this effort, we propose a new…

统计方法学 · 统计学 2024-10-10 Lin Ge , Yuzi Zhang , Lance A. Waller , Robert H. Lyles

Identifying super-spreaders in epidemics is important to suppress the spreading of disease especially when the medical resource is limited.In the modern society, the information on epidemics transmits swiftly through various communication…

物理与社会 · 物理学 2021-08-26 Qi Zeng , Ying Liu , Ming Tang , Jie Gong

Epidemic models often reflect characteristic features of infectious spreading processes by coupled non-linear differential equations considering different states of health (such as Susceptible, Infected, or Recovered). This compartmental…

物理与社会 · 物理学 2021-12-01 Vaiva Vasiliauskaite , Nino Antulov-Fantulin , Dirk Helbing

We consider real-time timely tracking of infection status (e.g., covid-19) of individuals in a population. In this work, a health care provider wants to detect infected people as well as people who recovered from the disease as quickly as…

计算机与社会 · 计算机科学 2020-12-29 Melih Bastopcu , Sennur Ulukus

We consider an age-structured epidemic model with two basic public health interventions: (i) identifying and isolating symptomatic cases, and (ii) tracing and quarantine of the contacts of identified infectives. The dynamics of the infected…

种群与进化 · 定量生物学 2014-03-13 Xi Huo

can evolve simultaneously. For the information-driven adaptive process, susceptible (infected) individuals who have abilities to recognize the disease would break the links of their infected (susceptible) neighbors to prevent the epidemic…

物理与社会 · 物理学 2015-05-20 Xiu-Xiu Zhan , Chuang Liu , Gui-Quan Sun , Zi-Ke Zhang

The last decade saw the advent of increasingly realistic epidemic models that leverage on the availability of highly detailed census and human mobility data. Data-driven models aim at a granularity down to the level of households or single…

种群与进化 · 定量生物学 2011-08-10 Nicola Perra , Duygu Balcan , Bruno Gonçalves , Alessandro Vespignani

In recent years social and news media have increasingly been used to explain patterns in disease activity and progression. Social media data, principally from the Twitter network, has been shown to correlate well with official disease case…

社会与信息网络 · 计算机科学 2015-04-17 Donal Simmie , Nicholas Thapen , Chris Hankin

Contact (or mixing, or more generally connectivity) matrices are a fundamental component of modelling and inference for infectious disease epidemiology. Their structure and parametrisation directly accounts for the frequency of interactions…

Traditional model-based diagnosis relies on constructing explicit system models, a process that can be laborious and expertise-demanding. In this paper, we propose a novel framework that combines concepts of model-based diagnosis with deep…

人工智能 · 计算机科学 2023-10-11 Jan Lukas Augustin , Oliver Niggemann

Disease-symptom datasets are significant and in demand for medical research, disease diagnosis, clinical decision-making, and AI-driven health management applications. These datasets help identify symptom patterns associated with specific…

计算与语言 · 计算机科学 2025-09-09 Abdullah Al Shafi , Rowzatul Zannat , Abdul Muntakim , Mahmudul Hasan

The outbreak of the novel coronavirus (COVID-19) is unfolding as a major international crisis whose influence extends to every aspect of our daily lives. Effective testing allows infected individuals to be quarantined, thus reducing the…

机器学习 · 计算机科学 2020-07-28 Rahul Singh , Fang Liu , Ness B. Shroff

Epidemic outbreaks of new pathogens, or known pathogens in new populations, cause a great deal of fear because they are hard to predict. For theoretical models of disease spreading, on the other hand, quantities characterizing the outbreak…

种群与进化 · 定量生物学 2015-05-20 Petter Holme , Taro Takaguchi

Current methods for the detection of contagious outbreaks give contemporaneous information about the course of an epidemic at best. Individuals at the center of a social network are likely to be infected sooner, on average, than those at…

物理与社会 · 物理学 2011-07-26 Nicholas A. Christakis , James H. Fowler

Identifying disease genes from human genome is an important and fundamental problem in biomedical research. Despite many publications of machine learning methods applied to discover new disease genes, it still remains a challenge because of…

定量方法 · 定量生物学 2017-05-23 Peng Yang

This paper gives an introduction to rule-based modelling applied to topics in infectious diseases. Rule-based models generalise reaction-based models with reagents that have internal state and may be bound together to form complexes, as in…

种群与进化 · 定量生物学 2021-08-10 William Waites , Matteo Cavaliere , David Manheim , Jasmina Panovska-Griffiths , Vincent Danos

The spread of infectious diseases crucially depends on the pattern of contacts among individuals. Knowledge of these patterns is thus essential to inform models and computational efforts. Few empirical studies are however available that…

Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

种群与进化 · 定量生物学 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

Influenza remains a significant burden on health systems. Effective responses rely on the timely understanding of the magnitude and the evolution of an outbreak. For monitoring purposes, data on severe cases of influenza in England are…