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mRNA-based vaccines have become a major focus in the pharmaceutical industry. The coding sequence as well as the Untranslated Regions (UTRs) of an mRNA can strongly influence translation efficiency, stability, degradation, and other factors…

基因组学 · 定量生物学 2025-03-12 Matthew Wood , Mathieu Klop , Maxime Allard

Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests…

机器学习 · 计算机科学 2019-08-20 Sterling Ramroach , Melford John , Ajay Joshi

The increasing focus on predicting renewable energy production aligns with advancements in deep learning (DL). The inherent variability of renewable sources and the complexity of prediction methods require robust approaches, such as DL…

机器学习 · 计算机科学 2025-12-05 Haibo Wang , Jun Huang , Lutfu Sua , Bahram Alidaee

Convolutional neural networks (CNNs) have constantly achieved better performance over years by introducing more complex topology, and enlarging the capacity towards deeper and wider CNNs. This makes the manual design of CNNs extremely…

计算机视觉与模式识别 · 计算机科学 2022-12-09 Bin Wang , Bing Xue , Mengjie Zhang

Deep Metric Learning (DML), a widely-used technique, involves learning a distance metric between pairs of samples. DML uses deep neural architectures to learn semantic embeddings of the input, where the distance between similar examples is…

机器学习 · 计算机科学 2021-02-16 Thomas Kobber Panum , Zi Wang , Pengyu Kan , Earlence Fernandes , Somesh Jha

First principle calculations of charge transfer in DNA molecules are computationally expensive given that charge carriers migrate in interaction with intra- and inter-molecular atomic motion. Screening sequences, e.g. to identify excellent…

介观与纳米尺度物理 · 物理学 2020-12-04 Roman Korol , Dvira Segal

Scattering networks are a class of designed Convolutional Neural Networks (CNNs) with fixed weights. We argue they can serve as generic representations for modelling images. In particular, by working in scattering space, we achieve…

Deep learning, through the use of neural networks, has demonstrated remarkable ability to automate many routine tasks when presented with sufficient data for training. The neural network architecture (e.g. number of layers, types of layers,…

Underwater explosions produce complex fluid phenomena relevant to diverse applications including maritime engineering, medical therapeutics, and inertial confinement fusion. These systems exhibit multiphase flows, chemical kinetics, and…

流体动力学 · 物理学 2025-07-02 Francis G. VanGessel , Mitul Pandya

Breast cancer is the most common cancer in the world and the most prevalent cause of death among women worldwide. Nevertheless, it is also one of the most treatable malignancies if detected early. In this paper, a deep convolutional neural…

计算机视觉与模式识别 · 计算机科学 2021-12-23 Hussin Ragb , Redha Ali , Elforjani Jera , Nagi Buaossa

Rheumatoid arthritis (RA) is an autoimmune condition caused when patients' immune system mistakenly targets their own tissue. Machine learning (ML) has the potential to identify patterns in patient electronic health records (EHR) to…

定量方法 · 定量生物学 2022-10-25 Shengjia Chen , Nikunj Gupta , Woodward B. Galbraith , Valay Shah , Jacopo Cirrone

The revolution in materials in the past century was built on a knowledge of the atomic arrangements and the structure-property relationship. The sine qua non for obtaining quantitative structural information is single crystal…

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray…

人工智能 · 计算机科学 2016-12-14 Rajendra Rana Bhat , Vivek Viswanath , Xiaolin Li

We have developed an image-based convolutional neural network (CNN) that is applicable for quantitative time-resolved measurements of the fragmentation behavior of opaque brittle materials using ultra-high speed optical imaging. This model…

材料科学 · 物理学 2024-07-19 Erwin Cazares , Brian E. Schuster

Regional rainfall forecasting is an important issue in hydrology and meteorology. This paper aims to design an integrated tool by applying various machine learning algorithms, especially the state-of-the-art deep learning algorithms…

机器学习 · 计算机科学 2021-03-30 Ning Yu , Timothy Haskins

We introduce a model-based deep learning architecture termed MoDL-MUSSELS for the correction of phase errors in multishot diffusion-weighted echo-planar MRI images. The proposed algorithm is a generalization of existing MUSSELS algorithm…

计算机视觉与模式识别 · 计算机科学 2019-10-23 Hemant Kumar Aggarwal , Merry P. Mani , Mathews Jacob

The lack of well-structured metadata annotations complicates there-usability and interpretation of the growing amount of publicly available RNA expression data. The machine learning-based prediction of metadata(data augmentation) can…

机器学习 · 计算机科学 2019-09-27 Jelena Fiosina , Maksims Fiosins , Stefan Bonn

The task of RNA design given a target structure aims to find a sequence that can fold into that structure. It is a computationally hard problem where some version(s) have been proven to be NP-hard. As a result, heuristic methods such as…

生物大分子 · 定量生物学 2024-12-13 Wei Yu Tang , Ning Dai , Tianshuo Zhou , David H. Mathews , Liang Huang

Recent advances in artificial intelligence (AI), specifically in computer vision (CV) and deep learning (DL), have created opportunities for novel systems in many fields. In the last few years, deep learning applications have demonstrated…

计算机视觉与模式识别 · 计算机科学 2018-03-15 Krunoslav Vinicki , Pierluigi Ferrari , Maja Belic , Romana Turk

Northern Europe has the second highest mortality rate of melanoma globally. In 2020, the mortality rate of melanoma rose to 1.9 per 100 000 habitants. Melanoma prognosis is based on a pathologist's subjective visual analysis of the…

图像与视频处理 · 电气工程与系统科学 2023-03-13 Christopher Andreassen , Saul Fuster , Helga Hardardottir , Emiel A. M. Janssen , Kjersti Engan