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Image mass cytometry (IMC) enables high-dimensional spatial profiling by combining mass cytometry's analytical power with spatial distributions of cell phenotypes. Recent studies leverage large language models (LLMs) to extract cell states…

计算与语言 · 计算机科学 2025-06-03 Chi-Jane Chen , Yuhang Chen , Sukwon Yun , Natalie Stanley , Tianlong Chen

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer aided detection and diagnosis systems based on deep learning have shown promising performance in breast cancer detection. However, there are cases where the obtained results lack justification. In this study, our objective is to…

计算机视觉与模式识别 · 计算机科学 2023-06-01 Imane Nedjar , Mohammed Brahimi , Said Mahmoudi , Khadidja Abi Ayad , Mohammed Amine Chikh

Malignant lymphoma subtype classification directly impacts treatment strategies and patient outcomes, necessitating classification models that achieve both high accuracy and sufficient explainability. This study proposes a novel explainable…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Daiki Nishiyama , Hiroaki Miyoshi , Noriaki Hashimoto , Koichi Ohshima , Hidekata Hontani , Ichiro Takeuchi , Jun Sakuma

Efficient and precise quantification of lymphocytes in histopathology slides is imperative for the characterization of the tumor microenvironment and immunotherapy response insights. We developed a data-centric optimization pipeline that…

图像与视频处理 · 电气工程与系统科学 2024-05-24 Amine Marzouki , Zhuxian Guo , Qinghe Zeng , Camille Kurtz , Nicolas Loménie

Colorectal cancer is a deadly disease that has become increasingly prevalent in recent years. Early detection is crucial for saving lives, but traditional diagnostic methods such as colonoscopy and biopsy have limitations. Colonoscopy…

机器学习 · 统计学 2023-07-18 Shangqing Tong , Peng Ge , Yanan Jiao , Zhaofu Ma , Ziye Li , Longhai Liu , Feng Gao , Xiaohui Du , Fei Gao

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

We propose 'Deep spatial context' (DSCon) method, which serves for investigation of the attention-based vision models using the concept of spatial context. It was inspired by histopathologists, however, the method can be applied to various…

计算机视觉与模式识别 · 计算机科学 2024-03-12 Paulina Tomaszewska , Elżbieta Sienkiewicz , Mai P. Hoang , Przemysław Biecek

Microscopic examination of slides prepared from tissue samples is the primary tool for detecting and classifying cancerous lesions, a process that is time-consuming and requires the expertise of experienced pathologists. Recent advances in…

计算机视觉与模式识别 · 计算机科学 2024-10-15 Saba Fatema , Brighton Nuwagira , Sayoni Chakraborty , Reyhan Gedik , Baris Coskunuzer

We propose a method for representing malignant lymphoma pathology images, from high-resolution cell nuclei to low-resolution tissue images, within a single hyperbolic space using self-supervised learning. To capture morphological changes…

计算机视觉与模式识别 · 计算机科学 2025-06-24 Kei Taguchi , Kazumasa Ohara , Tatsuya Yokota , Hiroaki Miyoshi , Noriaki Hashimoto , Ichiro Takeuchi , Hidekata Hontani

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

计算机视觉与模式识别 · 计算机科学 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Breast cancer is one of the factors that cause the increase of mortality of women. The most widely used method for diagnosing this geological disease i.e. breast cancer is the ultrasound scan. Several key features such as the smoothness and…

人工智能 · 计算机科学 2021-08-10 Mohamed Mejri , Aymen Mejri , Oumayma Mejri , Chiraz Fekih

In this work, we present Multi-Level Contrastive Learning for Dense Prediction Task (MCL), an efficient self-supervised method for learning region-level feature representation for dense prediction tasks. Our method is motivated by the three…

计算机视觉与模式识别 · 计算机科学 2023-04-05 Qiushan Guo , Yizhou Yu , Yi Jiang , Jiannan Wu , Zehuan Yuan , Ping Luo

Content-based medical image retrieval is an important diagnostic tool that improves the explainability of computer-aided diagnosis systems and provides decision making support to healthcare professionals. Medical imaging data, such as…

计算机视觉与模式识别 · 计算机科学 2022-11-23 Yunyan Xing , Benjamin J. Meyer , Mehrtash Harandi , Tom Drummond , Zongyuan Ge

We propose a patch sampling strategy based on a sequential Monte-Carlo method for high resolution image classification in the context of Multiple Instance Learning. When compared with grid sampling and uniform sampling techniques, it…

计算机视觉与模式识别 · 计算机科学 2019-01-01 Marc Combalia , Veronica Vilaplana

Recently, many methods to interpret and visualize deep neural network predictions have been proposed and significant progress has been made. However, a more class-discriminative and visually pleasing explanation is required. Thus, this…

计算机视觉与模式识别 · 计算机科学 2020-01-06 Dasom Seo , Kanghan Oh , Il-Seok Oh

One issue with computer based histopathology image analysis is that the size of the raw image is usually very large. Taking the raw image as input to the deep learning model would be computationally expensive while resizing the raw image to…

计算机视觉与模式识别 · 计算机科学 2019-03-01 Bolei Xu , Jingxin Liu , Xianxu Hou , Bozhi Liu , Jon Garibaldi , Ian O. Ellis , Andy Green , Linlin Shen , Guoping Qiu

Accurately classifying white blood cells from microscopic images is essential to identify several illnesses and conditions in medical diagnostics. Many deep learning technologies are being employed to quickly and automatically classify…

图像与视频处理 · 电气工程与系统科学 2025-08-07 Tatwadarshi P. Nagarhalli , Shruti S. Pawar , Soham A. Dahanukar , Uday Aswalekar , Ashwini M. Save , Sanket D. Patil

Skin cancer is one of the deadliest diseases and has a high mortality rate if left untreated. The diagnosis generally starts with visual screening and is followed by a biopsy or histopathological examination. Early detection can aid in…

计算机视觉与模式识别 · 计算机科学 2023-10-12 Mahapara Khurshid , Mayank Vatsa , Richa Singh
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