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Cardiac left ventricle (LV) quantification is among the most clinically important tasks for identification and diagnosis of cardiac diseases, yet still a challenge due to the high variability of cardiac structure and the complexity of…

计算机视觉与模式识别 · 计算机科学 2017-06-15 Wufeng Xue , Andrea Lum , Ashley Mercado , Mark Landis , James Warringto , Shuo Li

Purpose Tumor-infiltrating lymphocytes (TILs) have significant prognostic values in cancers. However, very few automated, deep-learning-based TIL scoring algorithms have been developed for colorectal cancers (CRC). Methods We developed an…

定量方法 · 定量生物学 2022-09-16 Anran Liu , Xingyu Li , Hongyi Wu , Bangwei Guo , Jitendra Jonnagaddala , Hong Zhang , Xu Steven Xu

Accurate prediction of recurrence in clear cell renal cell carcinoma (ccRCC) remains a major clinical challenge due to the disease complex molecular, pathological, and clinical heterogeneity. Traditional prognostic models, which rely on…

图像与视频处理 · 电气工程与系统科学 2025-07-11 Hasaan Maqsood , Saif Ur Rehman Khan

In today's world, a massive amount of data is available in almost every sector. This data has become an asset as we can use this enormous amount of data to find information. Mainly health care industry contains many data consisting of…

机器学习 · 计算机科学 2022-03-10 Hafsa Binte Kibria , Abdul Matin

Although fusion of information from multiple views of mammograms plays an important role to increase accuracy of breast cancer detection, developing multi-view mammograms-based computer-aided diagnosis (CAD) schemes still faces challenges…

计算机视觉与模式识别 · 计算机科学 2024-04-25 Xuxin Chen , Yuheng Li , Mingzhe Hu , Ella Salari , Xiaoqian Chen , Richard L. J. Qiu , Bin Zheng , Xiaofeng Yang

In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is a heterogeneous disease. Examining similarity and difference in the genetic basis of multiple subtypes of…

统计方法学 · 统计学 2013-04-18 Jin Liu , Jian Huang , Yawei Zhang , Qing Lan , Nathaniel Rothman , Tongzhang Zheng , Shuangge Ma

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

图像与视频处理 · 电气工程与系统科学 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Models for segmentation of brain lesions in multi-modal MRI are commonly trained for a specific pathology using a single database with a predefined set of MRI modalities, determined by a protocol for the specific disease. This work explores…

To facilitate early detection of breast cancer, there is a need to develop short-term risk prediction schemes that can prescribe personalized/individualized screening mammography regimens for women. In this study, we propose a new deep…

图像与视频处理 · 电气工程与系统科学 2024-12-05 Hong Hui Yeoh , Fredrik Strand , Raphaël Phan , Kartini Rahmat , Maxine Tan

Disorders of consciousness are a heterogeneous mixture of different diseases or injuries. Although some indicators and models have been proposed for prognostication, any single method when used alone carries a high risk of false prediction.…

In real-world scenarios, multi-view multi-label learning often encounters the challenge of incomplete training data due to limitations in data collection and unreliable annotation processes. The absence of multi-view features impairs the…

计算机视觉与模式识别 · 计算机科学 2025-03-25 Lian Zhao , Jie Wen , Xiaohuan Lu , Wai Keung Wong , Jiang Long , Wulin Xie

Developing reliable workload predictive models can affect many aspects of clinical decision making procedure. The primary challenge in healthcare systems is handling the demand uncertainty over the time. This issue becomes more critical for…

计算机与社会 · 计算机科学 2019-01-04 Mohammad Hessam Olya , Dongxiao Zhu , Kai Yang

Liver transplantation is a life-saving procedure for patients with end-stage liver disease. There are two main challenges in liver transplant: finding the best matching patient for a donor and ensuring transplant equity among different…

机器学习 · 计算机科学 2024-03-04 Can Li , Xiaoqian Jiang , Kai Zhang

Activity cliff prediction is a critical task in drug discovery and material design. Existing computational methods are limited to handling single binding targets, which restricts the applicability of these prediction models. In this paper,…

机器学习 · 计算机科学 2025-06-09 Zishan Shu , Yufan Deng , Hongyu Zhang , Zhiwei Nie , Jie Chen

Medical diagnosis requires the effective synthesis of visual manifestations and clinical metadata. However, existing methods often treat metadata as isolated tags, failing to exploit the rich semantic knowledge embedded in clinical…

计算机视觉与模式识别 · 计算机科学 2026-02-27 Yiqing Wang , Chunming He , Ming-Chen Lu , Mercy Pawar , Leslie Niziol , Maria Woodward , Sina Farsiu

Predicting clinical outcome is remarkably important but challenging. Research efforts have been paid on seeking significant biomarkers associated with the therapy response or/and patient survival. However, these biomarkers are generally…

机器学习 · 计算机科学 2020-10-09 Jiancheng Yang , Jiajun Chen , Kaiming Kuang , Tiancheng Lin , Junjun He , Bingbing Ni

Chronic liver disease represents a significant health challenge worldwide and accurate prognostic evaluations are essential for personalized treatment plans. Recent evidence suggests that integrating multimodal data, such as computed…

计算机视觉与模式识别 · 计算机科学 2025-02-04 Linglong Wu , Xuhao Shan , Ruiquan Ge , Ruoyu Liang , Chi Zhang , Yonghong Li , Ahmed Elazab , Huoling Luo , Yunbi Liu , Changmiao Wang

Ultrasound (US) is the primary imaging technique for the diagnosis of thyroid cancer. However, accurate identification of nodule malignancy is a challenging task that can elude less-experienced clinicians. Recently, many computer-aided…

图像与视频处理 · 电气工程与系统科学 2022-07-12 Van T. Manh , Jianqiao Zhou , Xiaohong Jia , Zehui Lin , Wenwen Xu , Zihan Mei , Yijie Dong , Xin Yang , Ruobing Huang , Dong Ni

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

图像与视频处理 · 电气工程与系统科学 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

Early identification of patients at risk of cardiovascular diseases (CVD) is crucial for effective preventive care, reducing healthcare burden, and improving patients' quality of life. This study demonstrates the potential of retinal…

图像与视频处理 · 电气工程与系统科学 2024-10-21 Cynthia Maldonado-Garcia , Arezoo Zakeri , Alejandro F Frangi , Nishant Ravikumar