相关论文: Fast, high precision autofocus on a motorised micr…
Bacterial heterogeneity is pivotal for adaptation to diverse environments, posing significant challenges in microbial diagnostics and therapeutic interventions. Recent advancements in high-resolution optical microscopy have revolutionized…
Miniature fluorescence microscopes are a standard tool in systems biology. However, widefield miniature microscopes capture only 2D information, and modifications that enable 3D capabilities increase the size and weight and have poor…
Malaria, a mosquito-borne disease caused by a parasite, kills over 1 million people globally each year. People, if left untreated, may develop severe complications, leading to death. Effective and accurate diagnosis is important for the…
In this article, we report an imaging method, termed Fourier ptychographic microscopy (FPM), which iteratively stitches together a number of variably illuminated, low-resolution intensity images in Fourier space to produce a wide-field,…
Malaria parasites pose a significant global health burden, causing widespread suffering and mortality. Detecting malaria infection accurately is crucial for effective treatment and control. However, existing automated detection techniques…
Malaria is a disease of global concern according to the World Health Organization. Billions of people in the world are at risk of Malaria today. Microscopy is considered the gold standard for Malaria diagnosis. Microscopic assessment of…
Malaria is a major health issue worldwide, and its diagnosis requires scalable solutions that can work effectively with low-cost microscopes (LCM). Deep learning-based methods have shown success in computer-aided diagnosis from microscopic…
Imaging of biological cells and tissues often relies on fluorescent labels, which offer high contrast with molecular specificity. The use of exogenous labeling agents, however, may alter the normal physiology of the bio-specimens.…
Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…
Autonomous migration is essential for the function of immune cells such as neutrophils and plays a pivotal role in diverse diseases. Recently, we introduced ComplexEye, a multi-lens array microscope comprising 16 independent…
Magnetic Resonance Imaging (MRI), including diffusion MRI (dMRI), serves as a ``microscope'' for anatomical structures and routinely mitigates the influence of low signal-to-noise ratio scans by compromising temporal or spatial resolution.…
Open source hardware has the potential to revolutionise the way we build scientific instruments; with the advent of readily-available 3D printers, mechanical designs can now be shared, improved and replicated faster and more easily than…
Recent advancements in whole slide imaging (WSI) have moved pathology closer to digital practice. Existing systems require precise mechanical control and the cost is prohibitive for most individual pathologists. Here we report a low-cost…
The capability of focus control has been central to optical technologies that require both high temporal and spatial resolutions. However, existing varifocal lens schemes are commonly limited to the response time on the microsecond…
Positioning patients for scanning and interventional procedures is a critical task that requires high precision and accuracy. The conventional workflow involves manually adjusting the patient support to align the center of the target body…
Aggregation-based assays, using micro- and nano-particles have been widely accepted as an efficient and cost-effective bio-sensing tool, particularly in microbiology, where particle clustering events are used as a metric to infer the…
Malaria, which primarily spreads with the bite of female anopheles mosquitos, often leads to death of people - specifically children in the age-group of 0-5 years. Clinical experts identify malaria by observing RBCs in blood smeared images…
Automation in optical microscopy is critical for enabling high-throughput imaging across a wide range of biomedical applications. Among the essential components of automated systems, robust autofocusing plays a pivotal role in maintaining…
Label-free nonlinear optical microscopy has become a powerful tool for biomedical research. However, the possible photodamage risk hinder further clinical applications. To reduce these adverse effects, we constructed a new platform of…
On-chip optical architectures that enable angle-resolved spectroscopy are essential for advancing photonic platforms towards low-volume, scalable, and cryo-compatible devices. Here, we introduce spatially resolved momentum-space imaging…