相关论文: MitoDet: Simple and robust mitosis detection

This is a write-up of our method submitted to Mitosis Domain Generalization (MIDOG 2021) Challenge held in MICCAI2021 conference.

Advanced image editing software enables easy creation of highly convincing image manipulations, which has been made even more accessible in recent years due to advances in generative AI. Manipulated images, while often harmless, could…

The MIDOG 2025 challenge extends prior work on mitotic figure detection by introducing a new Track 2 on atypical mitosis classification. This task aims to distinguish normal from atypical mitotic figures in histopathology images, a…

Mitotic figure detection is a crucial task in computational pathology, as mitotic activity serves as a strong prognostic marker for tumor aggressiveness. However, domain variability that arises from differences in scanners, tissue types,…

The domain shift between training and testing data presents a significant challenge for training generalizable deep learning models. As a consequence, the performance of models trained with the independent and identically distributed…

Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Domain shift presents a significant challenge in applying Deep Learning to the segmentation of 3D medical images from sources like Magnetic Resonance Imaging (MRI) and Computed Tomography (CT). Although numerous Domain Adaptation methods…

Machine learning algorithms have revolutionized different fields, including natural language processing, computer vision, signal processing, and medical data processing. Despite the excellent capabilities of machine learning algorithms in…

Leveraging synthetically rendered data offers great potential to improve monocular depth estimation and other geometric estimation tasks, but closing the synthetic-real domain gap is a non-trivial and important task. While much recent work…

Multiple-instance learning (MIL) is an attractive approach for digital pathology applications as it reduces the costs related to data collection and labelling. However, it is not clear how sensitive MIL is to clinically realistic domain…

With a continuously growing availability of annotated datasets of mitotic figures in histology images, finding the best way to optimally use with this unprecedented amount of data to optimally train deep learning models has become a new…

Image normalization is a building block in medical image analysis. Conventional approaches are customarily utilized on a per-dataset basis. This strategy, however, prevents the current normalization algorithms from fully exploiting the…

The problem of domain generalization is to take knowledge acquired from a number of related domains where training data is available, and to then successfully apply it to previously unseen domains. We propose a new feature learning…

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

Background: Image classification can be considered one of the key pillars of medical image analysis. Deep learning (DL) faces challenges that prevent its practical applications despite the remarkable improvement in medical image…

In AI-based histopathology, domain shifts are common and well-studied. However, this research focuses on stain and scanner variations, which do not show the full picture -- shifts may be combinations of other shifts, or "invisible" shifts…

Domain shifts in medical image segmentation, particularly when data comes from different centers, pose significant challenges. Intra-center variability, such as differences in scanner models or imaging protocols, can cause domain shifts as…

Mitotic counting is a vital prognostic marker of tumor proliferation in breast cancer. Deep learning-based mitotic detection is on par with pathologists, but it requires large labeled data for training. We propose a deep classification…

Mitosis detection is one of the challenging problems in computational pathology, and mitotic count is an important index of cancer grading for pathologists. However, current counts of mitotic nuclei rely on pathologists looking…

Domain Adaptation is a technique to address the lack of massive amounts of labeled data in unseen environments. Unsupervised domain adaptation is proposed to adapt a model to new modalities using solely labeled source data and unlabeled…