中文
相关论文

相关论文: Continuous Treatment Recommendation with Deep Surv…

200 篇论文

We investigate the task of estimating the conditional average causal effect of treatment-dosage pairs from a combination of observational data and assumptions on the causal relationships in the underlying system. This has been a…

机器学习 · 计算机科学 2022-05-31 Alexis Bellot , Anish Dhir , Giulia Prando

Estimating the causal effect of time-varying treatments on survival outcomes is a challenging task in many domains, particularly in medicine where treatment protocols adapt over time. While recent advances in representation learning have…

机器学习 · 统计学 2025-05-06 Ayoub Abraich

We study the problem of inferring heterogeneous treatment effects from time-to-event data. While both the related problems of (i) estimating treatment effects for binary or continuous outcomes and (ii) predicting survival outcomes have been…

机器学习 · 计算机科学 2022-01-25 Alicia Curth , Changhee Lee , Mihaela van der Schaar

In this work, we consider causal inference in various high-dimensional treatment settings, including for single multi-valued treatments and vector treatments with binary or continuous components, when the number of treatments can be…

统计理论 · 数学 2026-02-26 Patrick Kramer , Edward H. Kennedy , Isaac M. Opper

We consider the problem of estimating a dose-response curve. Continuous treatments arise often in practice, e.g. in the form of time spent on an operation, distance traveled to a location or dosage of a drug. Letting $A$ denote a continuous…

统计方法学 · 统计学 2026-04-14 Matteo Bonvini , Edward H. Kennedy

Existing causal methods for time-varying exposure and time-varying confounding focus on estimating the average causal effect of a time-varying binary treatment on an end-of-study outcome, offering limited tools for characterizing marginal…

统计方法学 · 统计学 2026-01-21 Yu Luo , Kuan Liu , Ramandeep Singh , Daniel J. Graham

In epidemiological research, modeling the cumulative effects of time-dependent exposures on survival outcomes presents a challenge due to their intricate temporal dynamics. Conventional spline-based statistical methods, though effective,…

机器学习 · 计算机科学 2026-01-01 Kang-Chung Yang , Shinsheng Yuan

Medical practitioners use survival models to explore and understand the relationships between patients' covariates (e.g. clinical and genetic features) and the effectiveness of various treatment options. Standard survival models like the…

Inferring the heterogeneous treatment effect is a fundamental problem in the sciences and commercial applications. In this paper, we focus on estimating Conditional Average Treatment Effect (CATE), that is, the difference in the conditional…

统计方法学 · 统计学 2021-03-23 Haomiao Meng , Xingye Qiao

Choosing the best treatment-plan for each individual patient requires accurate forecasts of their outcome trajectories as a function of the treatment, over time. While large observational data sets constitute rich sources of information to…

机器学习 · 计算机科学 2021-12-08 Jeroen Berrevoets , Alicia Curth , Ioana Bica , Eoin McKinney , Mihaela van der Schaar

Dynamic treatment regimes (DTRs) are critical to precision medicine, optimizing long-term outcomes through personalized, real-time decision-making in evolving clinical contexts, but require careful supervision for unsafe treatment risks.…

机器学习 · 计算机科学 2025-06-10 Yishan Shen , Yuyang Ye , Hui Xiong , Yong Chen

Cancer remains a leading cause of death worldwide, necessitating personalized treatment approaches to improve outcomes. Theranostics, combining molecular-level imaging with targeted therapy, offers potential for precision oncology but…

计算工程、金融与科学 · 计算机科学 2025-05-16 Binesh Sadanandan , Vahid Behzadan

This work bridges the gap between staggered adoption designs and survival analysis to estimate causal effects in settings with time-varying treatments, addressing a fundamental challenge in medical research exemplified by the Stanford Heart…

统计方法学 · 统计学 2025-03-04 Xiang Meng , Iavor Bojinov

We study the problem of estimating the effect function for a continuous treatment, which maps each treatment value to a population-averaged outcome. A central challenge in this setting is confounding: treatment assignment often depends on…

统计方法学 · 统计学 2026-05-29 Seok-Jin Kim , Kaizheng Wang

Dynamic treatment recommendation systems based on large-scale electronic health records (EHRs) become a key to successfully improve practical clinical outcomes. Prior relevant studies recommend treatments either use supervised learning…

机器学习 · 计算机科学 2018-09-18 Lu Wang , Wei Zhang , Xiaofeng He , Hongyuan Zha

When making treatment selection decisions, it is essential to include a causal effect estimation analysis to compare potential outcomes under different treatments or controls, assisting in optimal selection. However, merely estimating…

机器学习 · 统计学 2024-10-08 Sherly Alfonso-Sánchez , Kristina P. Sendova , Cristián Bravo

Dynamic prediction of causal effects under different treatment regimes conditional on an individual's characteristics and longitudinal history is an essential problem in precision medicine. This is challenging in practice because outcomes…

统计方法学 · 统计学 2023-03-07 Yizhen Xu , Jisoo Kim , Laura K. Hummers , Ami A. Shah , Scott Zeger

Drug repurposing is an effective strategy to identify new uses for existing drugs, providing the quickest possible transition from bench to bedside. Existing methods for drug repurposing that mainly focus on pre-clinical information may…

应用统计 · 统计学 2021-04-14 Ruoqi Liu , Lai Wei , Ping Zhang

Observational cohort data is an important source of information for understanding the causal effects of treatments on survival and the degree to which these effects are mediated through changes in disease-related risk factors. However,…

统计方法学 · 统计学 2026-05-20 Saurabh Bhandari , Michael J. Daniels , Juned Siddique

In medicine, researchers often seek to infer the effects of a given treatment on patients' outcomes. However, the standard methods for causal survival analysis make simplistic assumptions about the data-generating process and cannot capture…

机器学习 · 计算机科学 2022-10-28 Prayag Chatha , Yixin Wang , Zhenke Wu , Jeffrey Regier