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Accurate classification of Acute Lymphoblastic Leukemia (ALL) from peripheral blood smear images is essential for early diagnosis and effective treatment planning. This study investigates the use of transfer learning with pretrained…

图像与视频处理 · 电气工程与系统科学 2025-08-12 Faisal Ahmed

Leukemia, a severe form of blood cancer, claims thousands of lives each year. This study focuses on the detection of Acute Lymphoblastic Leukemia (ALL) using advanced image processing and deep learning techniques. By leveraging recent…

计算机视觉与模式识别 · 计算机科学 2025-01-14 Alaa Awad , Salah A. Aly

Acute Lymphoblastic Leukemia (ALL) accounts for the 80% of leukemias when coming down to pediatric ages. Survival of these patients has increased by a considerable amount in recent years. However, around 15-20% of treatments are…

While analysing rare blood cell aggregates remains challenging in automated haematology, they could markedly advance label-free functional diagnostics. Conventional flow cytometers efficiently perform cell counting with leukocyte…

This paper features convolutional neural networks defined on hypercomplex algebras applied to classify lymphocytes in blood smear digital microscopic images. Such classification is helpful for the diagnosis of acute lymphoblast leukemia…

计算机视觉与模式识别 · 计算机科学 2024-01-05 Guilherme Vieira , Marcos Eduardo Valle

Flow cytometry is often used to characterize the malignant cells in leukemia and lymphoma patients, traced to the level of the individual cell. Typically, flow cytometric data analysis is performed through a series of 2-dimensional…

机器学习 · 统计学 2009-11-13 Kevin M. Carter , Raviv Raich , William G. Finn , Alfred O. Hero

A mutation in the DNA of a single cell that compromises its function initiates leukemia,leading to the overproduction of immature white blood cells that encroach upon the space required for the generation of healthy blood cells.Leukemia is…

计算机视觉与模式识别 · 计算机科学 2025-01-27 Md. Abu Ahnaf Mollick , Md. Mahfujur Rahman , D. M. Asadujjaman , Abdullah Tamim , Nosin Anjum Dristi , Md. Takbir Hossen

Leukemia is the 10th most frequently diagnosed cancer and one of the leading causes of cancer-related deaths worldwide. Realistic analysis of leukemia requires white blood cell (WBC) localization, classification, and morphological…

计算机视觉与模式识别 · 计算机科学 2025-08-12 Abdul Rehman , Talha Meraj , Aiman Mahmood Minhas , Ayisha Imran , Mohsen Ali , Waqas Sultani , Mubarak Shah

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) are two major forms of leukemia that arise from lymphoid cells (LCs). ALL occurs mostly in children and CLL occurs mainly in old people. However, the…

细胞行为 · 定量生物学 2018-05-01 Jicun Wang-Michelitsch , Thomas M Michelitsch

Due to morphological similarity at the microscopic level, making an accurate and time-sensitive distinction between blood cells affected by Acute Lymphocytic Leukemia (ALL) and their healthy counterparts calls for the usage of machine…

计算机视觉与模式识别 · 计算机科学 2022-07-29 Sai Mattapalli , Rishi Athavale

Acute lymphoblastic leukemia (ALL) constitutes approximately 25% of the pediatric cancers. In general, the task of identifying immature leukemic blasts from normal cells under the microscope is challenging because morphologically the images…

计算机视觉与模式识别 · 计算机科学 2018-11-06 Simmi Mourya , Sonaal Kant , Pulkit Kumar , Anubha Gupta , Ritu Gupta

Complex phenotypic differences among different acute leukemias cannot be fully captured by analyzing the expression levels of one single molecule, such as a miR, at a time, but requires systematic analysis of large sets of miRs. While a…

Leukemia is diagnosed with complete blood counts which is by calculating all blood cells and compare the number of white blood cells (White Blood Cells / WBC) and red blood cells (Red Blood Cells / RBC). Information obtained from a complete…

计算机视觉与模式识别 · 计算机科学 2015-11-17 Esti Suryani , Wiharto Wiharto , Nizomjon Polvonov

Automatic detection of leukemic B-lymphoblast cancer in microscopic images is very challenging due to the complicated nature of histopathological structures. To tackle this issue, an automatic and robust diagnostic system is required for…

图像与视频处理 · 电气工程与系统科学 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Traditional health authority approval for oncology drugs is based on a clinical benefit endpoint, or a valid surrogate. In 1992 the FDA created the Accelerated Approval pathway to allow for earlier approval of therapies in serious…

应用统计 · 统计学 2026-02-26 Jane She , Xiaofei Chen , Malini Iyengar , Judy Li

Breast Cancer is the most prevalent cancer in the world. The World Health Organization reports that the disease still affects a significant portion of the developing world citing increased mortality rates in the majority of low to middle…

计算机视觉与模式识别 · 计算机科学 2021-08-23 Walt Williams , Jimmy Hall

Liquid biopsies (eg., blood draws) offer a less invasive and non-localized alternative to tissue biopsies for monitoring the progression of metastatic breast cancer (mBCa). Immunofluoresence (IF) microscopy is a tool to image and analyze…

计算机视觉与模式识别 · 计算机科学 2024-10-07 Evan Schwab , Bharat Annaldas , Nisha Ramesh , Anna Lundberg , Vishal Shelke , Xinran Xu , Cole Gilbertson , Jiyun Byun , Ernest T. Lam

Leukemia diagnosis primarily relies on manual microscopic analysis of bone marrow morphology supported by additional laboratory parameters, making it complex and time consuming. While artificial intelligence (AI) solutions have been…

Coronary Artery Disease (CAD) is one of the most common forms of heart disease, which is caused by a buildup of atherosclerotic plaque (known as stenosis) in the coronary arteries, leading to insufficient supplement of blood, oxygen, and…

计算工程、金融与科学 · 计算机科学 2024-09-06 Haizhou Yang , C. Alberto Figueroa , Krishna Garikipati