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Signal identification in large-dimensional settings is a challenging problem in biostatistics. Recently, the method of higher criticism (HC) was shown to be an effective means for determining appropriate decision thresholds. Here, we study…

统计方法学 · 统计学 2012-12-21 Bernd Klaus , Korbinian Strimmer

We consider the problem of variable selection in high-dimensional statistical models where the goal is to report a set of variables, out of many predictors $X_1, \dotsc, X_p$, that are relevant to a response of interest. For linear…

统计方法学 · 统计学 2019-03-20 Adel Javanmard , Hamid Javadi

A common approach to controlling complex networks is to directly control a subset of input nodes, which then controls the remaining nodes via network interactions. While techniques have been proposed for selecting input nodes based on…

最优化与控制 · 数学 2014-12-15 Andrew Clark , Basel Alomair , Linda Bushnell , Radha Poovendran

Controlling false discovery rate (FDR) while leveraging the side information of multiple hypothesis testing is an emerging research topic in modern data science. Existing methods rely on the test-level covariates while ignoring possible…

机器学习 · 统计学 2021-01-26 Lin Qiu , Nils Murrugarra-Llerena , Vítor Silva , Lin Lin , Vernon M. Chinchilli

There is a challenge in selecting high-dimensional mediators when the mediators have complex correlation structures and interactions. In this work, we frame the high-dimensional mediator selection problem into a series of hypothesis tests…

统计方法学 · 统计学 2025-09-16 Runqiu Wang , Ran Dai , Jieqiong Wang , Kah Meng Soh , Ziyang Xu , Mohamed Azzam , Hongying Dai , Cheng Zheng

Voxel-based multiple testing is widely used in neuroimaging data analysis. Traditional false discovery rate (FDR) control methods often ignore the spatial dependence among the voxel-based tests and thus suffer from substantial loss of…

机器学习 · 统计学 2024-05-06 Taehyo Kim , Hai Shu , Qiran Jia , Mony J. de Leon

A new approach to detect change points based on differential smoothing and multiple testing is presented for long data sequences modeled as piecewise constant functions plus stationary ergodic Gaussian noise. As an application of the STEM…

统计理论 · 数学 2019-11-20 Dan Cheng , Zhibing He , Armin Schwartzman

The stochastic block model is able to generate different network partitions, ranging from traditional assortative communities to disassortative structures. Since the degree-corrected stochastic block model does not specify which mixing…

社会与信息网络 · 计算机科学 2019-09-16 Xiaoyan Lu , Boleslaw K. Szymanski

Multiple hypothesis testing is a fundamental problem in high dimensional inference, with wide applications in many scientific fields. In genome-wide association studies, tens of thousands of tests are performed simultaneously to find if any…

统计方法学 · 统计学 2010-12-21 Xu Han , Weijie Gu , Jianqing Fan

The False Discovery Rate (FDR) is a new statistical procedure to control the number of mistakes made when performing multiple hypothesis tests, i.e. when comparing many data against a given model hypothesis. The key advantage of FDR is that…

Simultaneously performing variable selection and inference in high-dimensional regression models is an open challenge in statistics and machine learning. The increasing availability of vast amounts of variables requires the adoption of…

统计方法学 · 统计学 2025-05-08 Marco Molinari , Magne Thoresen

Effectively controlling the false discovery rate (FDR) in high-dimensional variable selection is a fundamental statistical problem that has garnered significant research interest. In this paper, we propose a novel, user-friendly, and…

统计方法学 · 统计学 2026-04-28 Yujia Wu , Panxu Yuan , Binyan Jiang

Graphical modelling techniques based on sparse selection have been applied to infer complex networks in many fields, including biology and medicine, engineering, finance, and social sciences. One structural feature of some of the networks…

统计理论 · 数学 2020-03-03 Annaliza McGillivray , Abbas Khalili , David A. Stephens

The recent proliferation of high-dimensional data, such as electronic health records and genetics data, offers new opportunities to find novel predictors of outcomes. Presented with a large set of candidate features, interest often lies in…

统计方法学 · 统计学 2024-09-24 Michael J. Martens , Anjishnu Banerjee , Xinran Qi , Yushu Shi

False discovery rate (FDR) control is a popular approach for maintaining the integrity of statistical analyses, especially in high-dimensional data settings, where multiple comparisons increase the risk of false positives. FDR control has…

信号处理 · 电气工程与系统科学 2026-03-03 Fabian Scheidt , Jasin Machkour , Michael Muma

Public data repositories have enabled researchers to compare results across multiple genomic studies in order to replicate findings. A common approach is to first rank genes according to an hypothesis of interest within each study. Then,…

应用统计 · 统计学 2012-06-29 Loki Natarajan , Minya Pu , Karen Messer

We develop a new class of distribution--free multiple testing rules for false discovery rate (FDR) control under general dependence. A key element in our proposal is a symmetrized data aggregation (SDA) approach to incorporating the…

统计方法学 · 统计学 2021-05-27 Lilun Du , Xu Guo , Wenguang Sun , Changliang Zou

Balancing false discovery rate (FDR) control with high statistical power remains a central challenge in high-dimensional variable selection. While several FDR-controlling methods have been proposed, many degrade the original data -- by…

统计方法学 · 统计学 2025-07-16 Changhu Wang , Ziheng Zhang , Jingyi Jessica Li

Network intrusion detection systems are an active area of research to identify threats that face computer networks. Network packets comprise of high dimensions which require huge effort to be examined effectively. As these dimensions…

密码学与安全 · 计算机科学 2017-07-19 Nour Moustafa , Jill Slay

This paper studies the estimation of high dimensional Gaussian graphical model (GGM). Typically, the existing methods depend on regularization techniques. As a result, it is necessary to choose the regularized parameter. However, the…

统计方法学 · 统计学 2013-06-06 Weidong Liu