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The projected increase of genotyping in the clinic and the rise of large genomic databases has led to the possibility of using patient medical data to perform genomewide association studies (GWAS) on a larger scale and at a lower cost than…

定量方法 · 定量生物学 2016-04-18 Sean Simmons , Cenk Sahinalp , Bonnie Berger

Genome-wide association studies (GWAS) are an essential tool in biomedical research for identifying genetic factors linked to health and disease. However, publicly releasing GWAS summary statistics poses well-recognized privacy risks,…

定量方法 · 定量生物学 2025-12-05 Anupama Nandi , Seth Neel , Hyunghoon Cho

Background: Clinical decision support systems (CDSS) are a category of health information technologies that can assist clinicians to choose optimal treatments. These support systems are based on clinical trials and expert knowledge;…

Motivated by tensions between data privacy for individual citizens, and societal priorities such as counterterrorism and the containment of infectious disease, we introduce a computational model that distinguishes between parties for whom…

数据结构与算法 · 计算机科学 2015-06-02 Michael Kearns , Aaron Roth , Zhiwei Steven Wu , Grigory Yaroslavtsev

In this paper, we attempt to provide a privacy-preserving and efficient solution for the "similar patient search" problem among several parties (e.g., hospitals) by addressing the shortcomings of previous attempts. We consider a scenario in…

密码学与安全 · 计算机科学 2020-02-04 Xiaojie Zhu , Erman Ayday , Roman Vitenberg , Narasimha Raghavan Veeraragavan

The recent spades of cyber security attacks have compromised end users' data safety and privacy in Medical Cyber-Physical Systems (MCPS). Traditional standard encryption algorithms for data protection are designed based on a viewpoint of…

密码学与安全 · 计算机科学 2019-04-18 Han Qiu , Meikang Qiu , Meiqin Liu , Gerard Memmi

The protection of privacy of individual-level information in genome-wide association study (GWAS) databases has been a major concern of researchers following the publication of "an attack" on GWAS data by Homer et al. (2008) Traditional…

应用统计 · 统计学 2014-02-10 Fei Yu , Stephen E. Fienberg , Aleksandra Slavković , Caroline Uhler

The problem we address is the following: how can a user employ a predictive model that is held by a third party, without compromising private information. For example, a hospital may wish to use a cloud service to predict the readmission…

机器学习 · 计算机科学 2014-12-25 Pengtao Xie , Misha Bilenko , Tom Finley , Ran Gilad-Bachrach , Kristin Lauter , Michael Naehrig

Patient datasets contain confidential information which is protected by laws and regulations such as HIPAA and GDPR. Ensuring comprehensive patient information necessitates privacy-preserving entity resolution (PPER), which identifies…

计算工程、金融与科学 · 计算机科学 2024-05-29 Yixiang Yao , Joseph Cecil , Praveen Angyan , Neil Bahroos , Srivatsan Ravi

Balancing the needs of data privacy and predictive utility is a central challenge for machine learning in healthcare. In particular, privacy concerns have led to a dearth of public datasets, complicated the construction of multi-hospital…

Healthcare data in cloud computing facilitates the treatment of patients efficiently by sharing information about personal health data between the healthcare providers for medical consultation. Furthermore, retaining the confidentiality of…

密码学与安全 · 计算机科学 2020-07-29 Pankaj Khatiwada , Hari Bhusal , Ayan Chatterjee , Martin W. Gerdess

The integration of cloud computing and Internet of Things (IoT) is quickly becoming the key enabler for the digital transformation of the healthcare industry by offering comprehensive improvements in patient engagements, productivity and…

密码学与安全 · 计算机科学 2017-02-14 Lei Yang , Qingji Zheng , Xinxin Fan

This work proposes a novel privacy-preserving cyberattack detection framework for blockchain-based Internet-of-Things (IoT) systems. In our approach, artificial intelligence (AI)-driven detection modules are strategically deployed at…

密码学与安全 · 计算机科学 2024-12-19 Bui Duc Manh , Chi-Hieu Nguyen , Dinh Thai Hoang , Diep N. Nguyen , Ming Zeng , Quoc-Viet Pham

Objective: To enable privacy-preserving learning of high quality generative and discriminative machine learning models from distributed electronic health records. Methods and Results: We describe general and scalable strategy to build…

密码学与安全 · 计算机科学 2018-06-19 Marina Blanton , Ah Reum Kang , Subhadeep Karan , Jaroslaw Zola

Traditional statistical methods for confidentiality protection of statistical databases do not scale well to deal with GWAS (genome-wide association studies) databases especially in terms of guarantees regarding protection from linkage to…

统计方法学 · 统计学 2012-05-04 Caroline Uhler , Aleksandra B. Slavkovic , Stephen E. Fienberg

Effective healthcare delivery depends on accurate longitudinal health records and addressing patients' concerns regarding the privacy of their information. While patient authentication is essential, reusing patient identifiers exposes…

密码学与安全 · 计算机科学 2026-03-10 Nasif Muslim , Jean-Charles Grégoire

Machine Learning on Big Data gets more and more attention in various fields. Even so privacy-preserving techniques become more important, even necessary due to legal regulations such as the General Data Protection Regulation (GDPR). On the…

密码学与安全 · 计算机科学 2022-01-28 Jasmin Zalonis , Frederik Armknecht , Björn Grohmann , Manuel Koch

This study introduces the development of a state of the art, real time ECG monitoring and analysis system, incorporating cutting edge medical technology and innovative data security measures. Our system performs three distinct functions…

密码学与安全 · 计算机科学 2024-11-05 Beyazit Bestami Yuksel , Ayse Yilmazer Metin

As genomic research has grown increasingly popular in recent years, dataset sharing has remained limited due to privacy concerns. This limitation hinders the reproducibility and validation of research outcomes, both of which are essential…

密码学与安全 · 计算机科学 2025-04-02 Yuzhou Jiang , Tianxi Ji , Erman Ayday

Motivation: Researchers need a rich trove of genomic datasets that they can leverage to gain a better understanding of the genetic basis of the human genome and identify associations between phenotypes and specific parts of DNA. However,…

密码学与安全 · 计算机科学 2021-06-10 Nour Almadhoun Alserr , Gulce Kale , Onur Mutlu , Oznur Tastan , Erman Ayday
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