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This study integrates PET metabolic information with CT anatomical structures to establish a 3D multimodal segmentation dataset for lymphoma based on whole-body FDG PET/CT examinations, which bridges the gap of the lack of standardised…

图像与视频处理 · 电气工程与系统科学 2025-12-08 Jiajun Ding , Beiyao Zhu , Xiaosheng Liu , Lishen Zhang , Zhao Liu

Virtual Imaging Trials (VIT) offer a cost-effective and scalable approach for evaluating medical imaging technologies. Computational phantoms, which mimic real patient anatomy and physiology, play a central role in VITs. However, the…

We present a novel approach for benchmarking and validating quantitative phase tomography (QPT) systems using three-dimensional microphantoms. These microphantoms, crafted from biological and imaging data, replicate the optical and…

The XCAT phantom is a realistic 4D digital torso phantom that is widely used in imaging and therapy research. However, lung mass is not conserved between respiratory phases of the phantom, making detailed dosimetric simulations and dose…

Background: X-ray dark-field imaging (XDFI) has been explored to provide superior performance over the conventional X-ray imaging for the diagnosis of many pathologic conditions. A simulation tool to reliably predict clinical XDFI images at…

医学物理 · 物理学 2024-07-18 Yongjin Sung , Brandon Nelson , Rajiv Gupta

Ultrasound computed tomography (USCT) is an emerging imaging modality for breast imaging that can produce quantitative images that depict the acoustic properties of tissues. Computer-simulation studies, also known as virtual imaging trials,…

医学物理 · 物理学 2022-06-24 Fu Li , Umberto Villa , Seonyeong Park , Mark A. Anastasio

Objectives: Computerized phantoms play an essential role in various applications of medical imaging research. Although the existing computerized phantoms can model anatomical variations through organ and phantom scaling, this does not…

图像与视频处理 · 电气工程与系统科学 2021-04-20 Junyu Chen , Ye Li , Yong Du , Eric C. Frey

Objective: This study aims to develop and validate a novel framework, iPhantom, for automated creation of patient-specific phantoms or digital-twins (DT) using patient medical images. The framework is applied to assess radiation dose to…

An automatic evidential segmentation method based on Dempster-Shafer theory and deep learning is proposed to segment lymphomas from three-dimensional Positron Emission Tomography (PET) and Computed Tomography (CT) images. The architecture…

计算机视觉与模式识别 · 计算机科学 2022-11-21 Ling Huang , Su Ruan , Pierre Decazes , Thierry Denoeux

Diffuse Large B-cell Lymphoma (DLBCL) is a lymphatic cancer involving one or more lymph nodes and extranodal sites. Its diagnostic and follow-up rely on Positron Emission Tomography (PET) and Computed Tomography (CT). After diagnosis, the…

Optoacoustic tomography (OAT) is a promising modality for breast cancer diagnosis because tumor angiogenesis and, potentially, hypoxia can be visualized using quantitative OAT (qOAT) techniques. Clinically meaningful inference generally…

医学物理 · 物理学 2025-10-02 Seonyeong Park , Gangwon Jeong , Umberto Villa , Mark A. Anastasio

Background: Accurate segmentation of diffuse large B-cell lymphoma (DLBCL) lesions is challenging due to their complex patterns in medical imaging. Objective: This study aims to develop a precise segmentation method for DLBCL using…

图像与视频处理 · 电气工程与系统科学 2024-09-10 Huan Huang , Liheng Qiu , Shenmiao Yang , Longxi Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Chen Zhao , Weihua Zhou

Sparsity of annotated data is a major limitation in medical image processing tasks such as registration. Registered multimodal image data are essential for the diagnosis of medical conditions and the success of interventional medical…

图像与视频处理 · 电气工程与系统科学 2021-07-26 Dominik F. Bauer , Tom Russ , Barbara I. Waldkirch , Christian Tönnes , William P. Segars , Lothar R. Schad , Frank G. Zöllner , Alena-Kathrin Golla

Recent studies have shown promising results in using Deep Learning to detect malignancy in whole slide imaging. However, they were limited to just predicting positive or negative finding for a specific neoplasm. We attempted to use Deep…

计算机视觉与模式识别 · 计算机科学 2018-11-08 Hanadi El Achi , Tatiana Belousova , Lei Chen , Amer Wahed , Iris Wang , Zhihong Hu , Zeyad Kanaan , Adan Rios , Andy N. D. Nguyen

Automatic lymph node segmentation is the cornerstone for advances in computer vision tasks for early detection and staging of cancer. Traditional segmentation methods are constrained by manual delineation and variability in operator…

图像与视频处理 · 电气工程与系统科学 2025-06-11 Jingguo Qu , Xinyang Han , Man-Lik Chui , Yao Pu , Simon Takadiyi Gunda , Ziman Chen , Jing Qin , Ann Dorothy King , Winnie Chiu-Wing Chu , Jing Cai , Michael Tin-Cheung Ying

Biophotonics is an active research area in molecular imaging, genetic diagnosis and prognosis, with direct applicability in precision medicine. However, long-standing challenges of biophotonics are well known due to low signal-to-noise…

医学物理 · 物理学 2017-10-02 Michael C Lun , Wei Zhang , Yue Zhao , Jeffrey Anker , Wenxiang Cong , Ge Wang , Changqing Li

Prostate cancer is a major global health concern, requiring advancements in robotic surgery and diagnostics to improve patient outcomes. A phantom is a specially designed object that simulates human tissues or organs. It can be used for…

医学物理 · 物理学 2025-08-25 Sizhe Tian , Yinoussa Adagolodjo , Jeremie Dequidt

Generative adversarial networks (GANs) have provided promising data enrichment solutions by synthesizing high-fidelity images. However, generating large sets of labeled images with new anatomical variations remains unexplored. We propose a…

图像与视频处理 · 电气工程与系统科学 2020-08-03 Sina Amirrajab , Samaneh Abbasi-Sureshjani , Yasmina Al Khalil , Cristian Lorenz , Juergen Weese , Josien Pluim , Marcel Breeuwer

Purpose: Digital phantoms are one of the key components of virtual imaging trials (VITs) that aim to assess and optimize new medical imaging systems and algorithms. However, these phantoms vary in their voxel resolution, appearance, and…

医学物理 · 物理学 2024-02-02 Amar Kavuri , Mini Das

Enlarged lymph nodes (LNs) can provide important information for cancer diagnosis, staging, and measuring treatment reactions, making automated detection a highly sought goal. In this paper, we propose a new algorithm representation of…

计算机视觉与模式识别 · 计算机科学 2014-08-15 Ari Seff , Le Lu , Kevin M. Cherry , Holger Roth , Jiamin Liu , Shijun Wang , Joanne Hoffman , Evrim B. Turkbey , Ronald M. Summers
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