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It is known that bipolar disorder and its lithium treatment involve the modulation of oxidative stress. Moreover, it has been observed that lithium's effects are isotope-dependent. Based on these findings, here we propose that lithium…

生物物理 · 物理学 2021-03-23 Hadi Zadeh-Haghighi , Christoph Simon

A large and growing body of research shows that weak magnetic fields can significantly influence various biological systems, including plants, animals, and humans. However, the underlying mechanisms behind these phenomena remain elusive. It…

生物物理 · 物理学 2022-04-21 Hadi Zadeh-Haghighi , Christoph Simon

The exact mechanism behind general anesthesia remains an open question in neuroscience. It has been proposed that anesthetics selectively prevent consciousness and memory via acting on microtubules (MTs). It is known that the magnetic field…

神经元与认知 · 定量生物学 2021-09-30 Hadi Zadeh-Haghighi , Christoph Simon

For the first time in history, humankind might conceivably begin to imagine itself as a multi-planetary species. This goal will entail technical innovation in a number of contexts, including that of healthcare. All life on Earth shares an…

Photoreduction of cryptochrome protein in the retina is a well-known mechanism of navigation of birds through the geomagnetic field, yet the biosignal nature of the mechanism remains unclear. The absorption of blue light by the flavin…

The radical pair mechanism is a leading hypothesis in animal magnetic navigation. This mechanism associates the magnetic sense with the visual system, the radical pairs in cryptochromes of the eye retina being specialized magnetic receptors…

生物物理 · 物理学 2018-02-09 Vladimir N. Binhi , Frank S. Prato

Cryptochrome flavoproteins are prime candidates for mediating magnetic sensing in migratory animals via the radical pair mechanism (RPM), a spin-dependent process initiated by photoinduced electron transfer. The canonical FAD-tryptophan…

生物大分子 · 定量生物学 2025-09-01 Zou Chengye , Liu Ya-jun , Wang Beibei

Circadian rhythms are archetypical examples of nonlinear oscillations. While these oscillations are usually attributed to circuits of biochemical interactions among clock genes and proteins, recent experimental studies reveal that they are…

One possible explanation for magnetosensing in biology, such as avian magnetoreception, is based on the spin dynamics of certain chemical reactions that involve radical pairs. Radical pairs have been suggested to also play a role in…

生物物理 · 物理学 2023-01-23 Hadi Zadeh-Haghighi , Christoph Simon

The N-methyl-D-aspartate receptor is a prominent player in brain development and functioning. Perturbations to its functioning through external stimuli like magnetic fields can potentially affect the brain in numerous ways. Various studies…

生物物理 · 物理学 2023-10-27 Parvathy S Nair , Hadi Zadeh-Haghighi , Christoph Simon

The mammalian circadian system comprises a network of cell-autonomous oscillators, spanning from the central clock in the brain to peripheral clocks in other organs. These clocks are tightly coordinated to orchestrate rhythmic physiological…

适应与自组织系统 · 物理学 2022-12-29 Yitong Huang , Yuanzhao Zhang , Rosemary Braun

Birds have a remarkable ability to obtain navigational information from the Earth's magnetic field. The primary detection mechanism of this compass sense is uncertain but appears to involve the quantum spin dynamics of radical pairs formed…

生物物理 · 物理学 2017-09-18 Daniel R. Kattnig , P. J. Hore

Magnetosensitive spin-correlated radical-pairs (SCRPs) offer a promising platform for noise-robust quantum metrology. However, unavoidable interradical interactions, such as electron-electron dipolar and exchange couplings, alongside…

量子物理 · 物理学 2026-02-25 Luke D. Smith , Farhan T. Chowdhury , Jonas Glatthard , Daniel R. Kattnig

Radical pairs and the dynamics they undergo are prevalent in many chemical and biological systems. Specifically, it has been proposed that the radical pair mechanism results from a relatively strong hyperfine interaction with its intrinsic…

量子物理 · 物理学 2021-03-26 Amit Finkler , Durga Dasari

The mechanism used by migratory birds to orientate themselves using the geomagnetic field is still a mystery in many species. The radical pair mechanism, in which very weak magnetic fields can influence certain types of spin-dependent…

生物物理 · 物理学 2013-09-24 Neill Lambert , Simone De Liberato , Clive Emary , Franco Nori

In order to investigate whether the radical pair mechanism (RPM) can explain the effects of telecommunication frequency radiation on reactive oxygen species production, we modelled the effects of oscillating magnetic fields on radical pair…

生物物理 · 物理学 2024-07-08 Owaiss Talbi , Hadi Zadeh-Haghighi , Christoph Simon

Planarian is an intriguing model system wherein the effect of electric and magnetic fields can be studied on various biochemical pathways during cell morphogenesis. Recent experimental observations have demonstrated the non-trivial…

生物物理 · 物理学 2024-03-04 Yash Tiwari , Parul Raghuvanshi , Vishvendra Singh Poonia

We review the spin radical pair mechanism which is a promising explanation of avian navigation. This mechanism is based on the dependence of product yields on (1) the hyperfine interaction involving electron spins and neighboring nuclear…

生物物理 · 物理学 2015-03-24 Yiteng Zhang , Gennady P. Berman , Sabre Kais

The radical pair reaction underlies the magnetic field sensitivity of chemical reactions and is suggested to play an important role in both chemistry and biology. Current experimental evidence is based on ensemble measurements, however, the…

量子物理 · 物理学 2017-05-30 Haibin Liu , Martin B. Plenio , Jianming Cai

The yield of chemical reactions involving intermediate radical pairs is influenced by magnetic fields well beyond the levels expected from energy considerations. This dependence can be traced back to the microscopic dynamics of electron…

生物物理 · 物理学 2013-05-29 Gian Giacomo Guerreschi , Markus Tiersch , Ulrich E. Steiner , Hans J. Briegel
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