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Uterine leiomyosarcoma (LMS) is a rare but aggressive malignancy. On imaging, it is difficult to differentiate LMS from, for example, degenerated leiomyoma (LM), a prevalent but benign condition. We curated a data set of 115 axial…

Breast cancer is the most common cancer among women both in developed and developing countries. Early detection and diagnosis of breast cancer may reduce its mortality and improve the quality of life. Computer-aided detection (CADx) and…

Uterine fibroids (myomas) are the most common benign tumors of the female reproductive system, particularly among women of childbearing age. With a prevalence exceeding 70%, they pose a significant burden on female reproductive health.…

Endometrial cancer, the fourth most common cancer in females in the United States, with the lifetime risk for developing this disease is approximately 2.8% in women. Precise histologic evaluation and molecular classification of endometrial…

Melanoma is the deadliest form of skin cancer. While curable with early detection, only highly trained specialists are capable of accurately recognizing the disease. As expertise is in limited supply, automated systems capable of…

Early detection of myometrial invasion is critical for the staging and life-saving management of endometrial carcinoma (EC), a prevalent global malignancy. Transvaginal ultrasound serves as the primary, accessible screening modality in…

Diagnosis of breast carcinomas has so far been limited to the morphological interpretation of epithelial cells and the assessment of epithelial tissue architecture. Consequently, most of the automated systems have focused on characterizing…

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Cervical spondylosis (CS) is a common chronic disease that affects up to two-thirds of the population and poses a serious burden on individuals and society. The early identification has significant value in improving cure rate and reducing…

Endometrial cancer is one of the most common tumors in the female reproductive system and is the third most common gynecological malignancy that causes death after ovarian and cervical cancer. Early diagnosis can significantly improve the…

Assessing the pre-operative risk of lymph node metastases in endometrial cancer patients is a complex and challenging task. In principle, machine learning and deep learning models are flexible and expressive enough to capture the dynamics…

We present an Expectation-Maximization (EM) Regularized Deep Learning (EMReDL) model for weakly supervised tumor segmentation. The proposed framework is tailored to glioblastoma, a type of malignant tumor characterized by its diffuse…

Developing an AI-assisted gland segmentation method from histology images is critical for automatic cancer diagnosis and prognosis; however, the high cost of pixel-level annotations hinders its applications to broader diseases. Existing…

Breast cancer ranks as the most prevalent form of cancer diagnosed in women, and diagnosis faces several challenges, a change in the size, shape and appearance of breasts, dense breast tissue, lumps or thickening in the breast especially if…

Osteosarcoma is the most common primary malignant bone tumor, which has high mortality due to easy lung metastasis. Osteosarcoma is a highly anaplastic, pleomorphic tumor with a variety of tumor cell morphology, including fusiform, oval,…

For prostate cancer patients, the Gleason score is one of the most important prognostic factors, potentially determining treatment independent of the stage. However, Gleason scoring is based on subjective microscopic examination of tumor…

The presence of tertiary lymphoid structures (TLSs) on pancreatic pathological images is an important prognostic indicator of pancreatic tumors. Therefore, TLSs detection on pancreatic pathological images plays a crucial role in diagnosis…

Breast cancer is one of the most major causes of death among women, after lung cancer. Breast cancer detection advancements can increase the survival rate of patients through earlier detection. Breast cancer that can be detected by using…

Gastric cancer is the fifth most common cancer in the world. At the same time, it is also the fourth most deadly cancer. Early detection of cancer exists as a guide for the treatment of gastric cancer. Nowadays, computer technology has…

Early diagnosis of cancer often allows for a more vast choice of therapy opportunities. After a cancer diagnosis, staging provides essential information about the extent of disease in the body and the expected response to a particular…