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Histo-pathological diagnostics are an inherent part of the everyday work but are particularly laborious and associated with time-consuming manual analysis of image data. In order to cope with the increasing diagnostic case numbers due to…

Single-cell transcriptomics and proteomics have become a great source for data-driven insights into biology, enabling the use of advanced deep learning methods to understand cellular heterogeneity and gene expression at the single-cell…

基因组学 · 定量生物学 2025-12-15 Hiren Madhu , João Felipe Rocha , Tinglin Huang , Siddharth Viswanath , Smita Krishnaswamy , Rex Ying

Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…

Cell detection, segmentation and classification are essential for analyzing tumor microenvironments (TME) on hematoxylin and eosin (H&E) slides. Existing methods suffer from poor performance on understudied cell types (rare or not present…

Blood cell classification and counting are vital for the diagnosis of various blood-related diseases, such as anemia, leukemia, and thrombocytopenia. The manual process of blood cell classification and counting is time-consuming, prone to…

The diagnosis of blood-based diseases often involves identifying and characterizing patient blood samples. Automated methods to detect and classify blood cell subtypes have important medical applications. Automated medical image processing…

计算机视觉与模式识别 · 计算机科学 2021-06-24 Sai Sukruth Bezugam

Malignant lymphoma subtype classification directly impacts treatment strategies and patient outcomes, necessitating classification models that achieve both high accuracy and sufficient explainability. This study proposes a novel explainable…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Daiki Nishiyama , Hiroaki Miyoshi , Noriaki Hashimoto , Koichi Ohshima , Hidekata Hontani , Ichiro Takeuchi , Jun Sakuma

Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process…

图像与视频处理 · 电气工程与系统科学 2025-03-03 Ajinkya Deshpande , Deep Gupta , Ankit Bhurane , Nisha Meshram , Sneha Singh , Petia Radeva

Immunofluorescent (IF) imaging is crucial for visualizing biomarker expressions, cell morphology and assessing the effects of drug treatments on sub-cellular components. IF imaging needs extra staining process and often requiring cell…

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

图像与视频处理 · 电气工程与系统科学 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori

Machine learning has endless applications in the health care industry. White blood cell classification is one of the interesting and promising area of research. The classification of the white blood cells plays an important part in the…

计算机视觉与模式识别 · 计算机科学 2021-12-14 Nalla Praveen , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal , M. Syafrullah , Krisna Adiyarta

Cancer is the uncontrollable cell division of abnormal cells inside the human body, which can spread to other body organs. It is one of the non-communicable diseases (NCDs) and NCDs accounts for 71% of total deaths worldwide whereas lung…

图像与视频处理 · 电气工程与系统科学 2021-12-28 Neha Baranwal , Preethi Doravari , Renu Kachhoria

Explainability is a key requirement for computer-aided diagnosis systems in clinical decision-making. Multiple instance learning with attention pooling provides instance-level explainability, however for many clinical applications a deeper,…

图像与视频处理 · 电气工程与系统科学 2023-03-16 Ario Sadafi , Oleksandra Adonkina , Ashkan Khakzar , Peter Lienemann , Rudolf Matthias Hehr , Daniel Rueckert , Nassir Navab , Carsten Marr

Accurate skin cancer diagnosis is vital for early treatment and improved patient outcomes. Deep learning (DL) models have shown promise in automating skin cancer classification, yet challenges remain due to data scarcity and limited…

计算机视觉与模式识别 · 计算机科学 2025-09-25 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

Pigmented skin lesions represent localized areas of increased melanin and can indicate serious conditions like melanoma, a major contributor to skin cancer mortality. The MedMNIST v2 dataset, inspired by MNIST, was recently introduced to…

图像与视频处理 · 电气工程与系统科学 2025-07-18 Nerma Kadric , Amila Akagic , Medina Kapo

An automatic evidential segmentation method based on Dempster-Shafer theory and deep learning is proposed to segment lymphomas from three-dimensional Positron Emission Tomography (PET) and Computed Tomography (CT) images. The architecture…

计算机视觉与模式识别 · 计算机科学 2022-11-21 Ling Huang , Su Ruan , Pierre Decazes , Thierry Denoeux

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Acute lymphoblastic leukemia (ALL) severity is determined by the presence and ratios of blast cells (abnormal white blood cells) in both bone marrow and peripheral blood. Manual diagnosis of this disease is a tedious and time-consuming…

计算机视觉与模式识别 · 计算机科学 2024-08-13 Amir Masoud Rahmani , Parisa Khoshvaght , Hamid Alinejad-Rokny , Samira Sadeghi , Parvaneh Asghari , Zohre Arabi , Mehdi Hosseinzadeh

Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…

计算机视觉与模式识别 · 计算机科学 2022-03-01 Steve Tsham Mpinda Ataky , Alessandro Lameiras Koerich

Orthopoxvirus infections must be accurately classified from medical pictures for an easy and early diagnosis and epidemic prevention. The necessity for automated and scalable solutions is highlighted by the fact that traditional diagnostic…

计算机视觉与模式识别 · 计算机科学 2025-06-09 Alejandro Puente-Castro , Enrique Fernandez-Blanco , Daniel Rivero , Andres Molares-Ulloa
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