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Microbiomes not only underpin Earth's biogeochemical cycles but also play crucial roles in both engineered and natural ecosystems, such as the soil, wastewater treatment, and the human gut. However, microbiome engineering faces significant…

机器学习 · 计算机科学 2025-09-03 Mingzhi Dai , Weiwei Cai , Xiang Feng , Huiqun Yu , Weibin Guo , Miao Guo

Metagenomic data has significantly advanced microbiome research by employing ecological models, particularly in personalised medicine. The generalised Lotka-Volterra (gLV) model is commonly used to understand microbial interactions and…

种群与进化 · 定量生物学 2025-10-07 Mario Castro , Rafael Vida , Javier Galeano , José A. Cuesta

This paper proposes a hierarchical Bayesian multitask learning model that is applicable to the general multi-task binary classification learning problem where the model assumes a shared sparsity structure across different tasks. We derive a…

Nowadays, water reuse is a serious challenge to help address water shortages. Here, the wastewater treatment plants (WWTP) play a key role, and its proper operation is mandatory. So, fault diagnosis is a key activity for these plants. Their…

系统与控制 · 电气工程与系统科学 2025-06-11 Alicia Beneyto-Rodriguez , Gregorio I. Sainz-Palmero , Marta Galende-Hernández , María J. Fuente

This work proposes an automatic control solution for the operation of conventional wastewater treatment plants (WWTPs) as energy-autonomous water resource recovery facilities. We first conceptualize a classification of the quality of…

系统与控制 · 电气工程与系统科学 2025-06-13 Otacilio B. L. Neto , Michela Mulas , Iiro Harjunkoski , Francesco Corona

16S-ribosomal sequencing and other metagonomic techniques provide snapshots of microbial communities, revealing phylogeny and the abundances of microbial populations across diverse ecosystems. While changes in microbial community structure…

Human microbiome studies use sequencing technologies to measure the abundance of bacterial species or Operational Taxonomic Units (OTUs) in samples of biological material. Typically the data are organized in contingency tables with OTU…

统计方法学 · 统计学 2017-03-27 Boyu Ren , Sergio Bacallado , Stefano Favaro , Susan Holmes , Lorenzo Trippa

Human associated microbial communities exert tremendous influence over human health and disease. With modern metagenomic sequencing methods it is possible to follow the relative abundance of microbes in a community over time. These…

定量方法 · 定量生物学 2015-06-18 Charles K. Fisher , Pankaj Mehta

The human body consists of microbiomes associated with the development and prevention of several diseases. These microbial organisms form several complex interactions that are informative to the scientific community for explaining disease…

统计方法学 · 统计学 2024-04-16 Tejasv Bedi , Bencong Zhu , Michael L. Neugent , Kevin C. Lutz , Nicole J. De Nisco , Qiwei Li

In this paper, we present two years of high-resolution nitrous oxide ($N_2O$) measurements for time series modeling and forecasting in wastewater treatment plants (WWTP). The dataset comprises frequent, real-time measurements from a…

During the last decades macroecology has identified broad-scale patterns of abundances and diversity of microbial communities and put forward some potential explanations for them. However, these advances are not paralleled by a full…

种群与进化 · 定量生物学 2024-01-26 José Camacho-Mateu , Aniello Lampo , Matteo Sireci , Miguel Ángel Muñoz , José A. Cuesta

Inferring microbial community structure based on temporal metagenomics data is an important goal in microbiome studies. The deterministic generalized Lotka-Volterra differential (GLV) equations have been used to model the dynamics of…

统计方法学 · 统计学 2020-09-24 Libai Xu , Ximing Xu , Dehan Kong , Hong Gu , Toby Kenney

Classical approaches to ecological stability rely on fully connected interaction models, yet real ecosystems are sparse and structured--a feature that qualitatively reshapes their collective dynamics. Here, we establish a thermodynamically…

无序系统与神经网络 · 物理学 2025-12-30 Mattia Tarabolo , Luca Dall'Asta , Roberto Mulet

Anaerobic digestion (AD) offers a sustainable biotechnology to recover resources from carbon-rich wastewater, such as food-processing wastewater. Despite crude wastewater characterisation, the impact of detailed chemical fingerprinting on…

定量方法 · 定量生物学 2025-01-14 Ellen Piercy , Xinyang Sun , Peter R Ellis , Mark Taylor , Miao Guo

Microbes are everywhere, including in and on our bodies, and have been shown to play key roles in a variety of prevalent human diseases. Consequently, there has been intense interest in the design of bacteriotherapies or "bugs as drugs,"…

机器学习 · 统计学 2020-04-13 Travis E. Gibson , Georg K. Gerber

Model-based solutions for nitrous oxide (N2O) emissions from wastewater treatment plants (WWTP) are informed by operational datasets designed to control nutrient levels in liquid waste, coupled with dedicated campaigns for N2O measurements.…

机器学习 · 计算机科学 2026-05-07 Mohammad Raeisi Gahrouei , Pedram Ramin , Vincenzo A. Riggio , Carlos Domingo-Felez

Wastewater-based epidemiology (WBE) is an effective tool for tracking community circulation of respiratory viruses. We address estimating the effective reproduction number ($R_t$) and the relative number of infections from wastewater viral…

Generating energy functions for heterogeneous systems suitable for quantitative and predictive atomistic simulations is a challenging undertaking. The present work combines a cluster-based approach with electronic structure calculations at…

化学物理 · 物理学 2025-03-03 Kai Töpfer , Jingchun Wang , Shimoni Patel , Markus Meuwly

We introduce a flexible, scalable Bayesian inference framework for nonlinear dynamical systems characterised by distinct and hierarchical variability at the individual, group, and population levels. Our model class is a generalisation of…

机器学习 · 统计学 2019-10-03 Geoffrey Roeder , Paul K. Grant , Andrew Phillips , Neil Dalchau , Edward Meeds

The rapid advancement of environmental sequencing technologies, such as metagenomics, has significantly enhanced our ability to study microbial communities. The eubiotic composition of these communities is crucial for maintaining ecological…

无序系统与神经网络 · 物理学 2025-08-27 Jacopo Pasqualini , Amos Maritan , Andrea Rinaldo , Sonia Facchin , Edoardo Savarino , Ada Altieri , Samir Suweis
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