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We consider the dynamics of a rigid filament in a motor protein assay under external loading. The motor proteins are modeled as active harmonic linkers with tail ends immobilized on a substrate. Their heads attach to the filament…

生物物理 · 物理学 2021-12-23 Amir Shee , Subhadip Ghosh , Debasish Chaudhuri

The rotary motor of bacteria is a natural nano-technological marvel that enables cell locomotion by powering the rotation of semi-rigid helical flagellar filaments in fluid environments. It is well known that the motor operates essentially…

生物物理 · 物理学 2018-10-23 Debasish Das , Eric Lauga

Cilia and flagella are essential building blocks for biological fluid transport and locomotion at the micron scale. They often beat in synchrony and may transition between different synchronization modes in the same cell type. Here, we…

流体动力学 · 物理学 2018-02-14 Hanliang Guo , Lisa Fauci , Michael Shelley , Eva Kanso

We study the dynamics and interaction of two swimming bacteria, modeled by self-propelled dumbbell-type structures. We focus on alignment dynamics of a coplanar pair of elongated swimmers, which propel themselves either by pushing" or…

偏微分方程分析 · 数学 2008-11-24 Vitaliy Gyrya , Igor S. Aranson , Leonid V. Berlyand , Dmitry Karpeev

Although the auger-like 'swimming' motility of the African trypanosome was described upon its discovery over one hundred years ago, the precise biomechanical and biophysical properties of trypanosome flagellar motion has not been…

生物物理 · 物理学 2016-09-08 D. Fry , N. Hutchings , A. Ludu

Scombrid fishes and tuna are efficient swimmers capable of maximizing performance to escape predators and save energy during long journeys. A key aspect in achieving these goals is the flexibility of the tail, which the fish optimizes…

流体动力学 · 物理学 2024-11-19 L. Padovani , G. Manduca , D. Paniccia , G. Graziani , R. Piva , C. Lugni

We present a minimal physical model for the flagellar motor that enables bacteria to swim. Our model explains the experimentally measured torque-speed relationship of the proton-driven E. coli motor at various pH and temperature conditions.…

亚细胞过程 · 定量生物学 2009-12-11 Thierry Mora , Howard Yu , Ned S. Wingreen

Near-field hydrodynamic interactions between bacteria and no-slip solid surfaces are the main mechanism underlying surface entrapment of bacteria. In this study, we employ a chiral two-body model to simulate bacterial dynamics near the…

软凝聚态物质 · 物理学 2026-02-25 Baopi Liu , Lu Chen , Haiqin Wang

Active swimmers are ubiquitous in nature, found in many diverse biological systems ranging from bacteria to vertebrate fish. Of particular importance are sperm cells which are swimmers that are crucial for the survival of many species…

生物物理 · 物理学 2017-11-15 James L. Kingsley , Utkan Demirci , Erkan Tuzel

Liquid-liquid phase separation is important across biology, physics, and materials science. Although usually studied at equilibrium, active components - such as motor proteins, enzymes, and synthetic microswimmers - are increasingly…

软凝聚态物质 · 物理学 2026-01-06 Kan Chang , Yulin Li , Ming Yuan , Masaki Sano , Zhihong You , H. P. Zhang

Biological filaments such as DNA or bacterial flagella are typically curved in their natural states. To elucidate the interplay of viscous drag, twisting, and bending in the overdamped dynamics of such filaments, we compute the steady-state…

软凝聚态物质 · 物理学 2009-10-31 Stephan A. Koehler , Thomas R. Powers

Cellular appendages conferring motility, such as flagella or cilia, are known to synchronise their periodic beats. The origin of synchronisation is a combination of long-range hydrodynamic interactions with physical mechanisms allowing the…

生物物理 · 物理学 2021-04-21 Ivan Tanasijević , Eric Lauga

We study the force production dynamics of undulating elastic plates as a model for fish-like inertial swimmers. Using a beam model coupled with Lighthill's large-amplitude elongated-body theory, we explore different localised actuations at…

流体动力学 · 物理学 2017-12-25 Miguel Piñeirua , Benjamin Thiria , Ramiro Godoy-Diana

The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in…

细胞行为 · 定量生物学 2016-06-29 Davide Ambrosi , Anna Zanzottera

Sperm are propelled by bending waves travelling along the flagellum. During steering in gradients of sensory cues, sperm adjust the flagellar beat waveform. Symmetric and asymmetric beat waveforms produce straight and curved swimming paths,…

Synchronization induced by long-range hydrodynamic interactions is attracting attention as a candidate mechanism behind coordinated beating of cilia and flagella. Here we consider a minimal model of hydrodynamic synchronization in the low…

软凝聚态物质 · 物理学 2012-11-26 Nariya Uchida , Ramin Golestanian

Bacterial mobility is powered by rotation of helical flagellar filaments driven by rotary motors. Flagellin isolated from {\it Salmonella Typhimurium} SJW1660 strain, which differs by a point mutation from the wild-type strain, assembles…

生物大分子 · 定量生物学 2017-06-28 D. Louzon , A. Ginsburg , W. Schwenger , T. Dvir , Z. Dogic , U. Raviv

The persistent dynamics of active particles makes them explore extended portions of an obstacle's boundary during collisions. From impact to escape, the net applied forces depend on the curvature of the wall and increase in the presence of…

The physical basis of flagellar and ciliary beating is a major problem in biology which is still far from completely understood. The fundamental cytoskeleton structure of cilia and flagella is the axoneme, a cylindrical array of microtubule…

生物物理 · 物理学 2017-03-10 David Oriola , Hermes Gadêlha , Jaume Casademunt

The deformation of thin rods in a viscous liquid is central to the mechanics of motility in cells ranging from \textit{Escherichia coli} to sperm. Here we use experiments and theory to study the shape transition of a flexible rod rotating…

软凝聚态物质 · 物理学 2008-02-26 Bian Qian , Thomas R. Powers , Kenneth S. Breuer