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We consider a method for approximate inference in hidden Markov models (HMMs). The method circumvents the need to evaluate conditional densities of observations given the hidden states. It may be considered an instance of Approximate…

统计计算 · 统计学 2012-06-25 James S. Martin , Ajay Jasra , Sumeetpal S. Singh , Nick Whiteley , Emma McCoy

Missing values exist in nearly all clinical studies because data for a variable or question are not collected or not available. Inadequate handling of missing values can lead to biased results and loss of statistical power in analysis.…

机器学习 · 计算机科学 2021-03-04 Narges Pourshahrokhi , Samaneh Kouchaki , Kord M. Kober , Christine Miaskowski , Payam Barnaghi

Bayesian Model Calibration is used to revisit the problem of scaling factor calibration for semi-empirical correction of ab initio calculations. A particular attention is devoted to uncertainty evaluation for scaling factors, and to their…

数据分析、统计与概率 · 物理学 2009-01-12 Pascal Pernot

Modern large-scale statistical models require to estimate thousands to millions of parameters. This is often accomplished by iterative algorithms such as gradient descent, projected gradient descent or their accelerated versions. What are…

机器学习 · 统计学 2020-03-04 Michael Celentano , Andrea Montanari , Yuchen Wu

In machine learning and statistics, probabilistic inference involving multimodal distributions is quite difficult. This is especially true in high dimensional problems, where most existing algorithms cannot easily move from one mode to…

统计计算 · 统计学 2015-06-22 Shiwei Lan , Jeffrey Streets , Babak Shahbaba

When working with multimodal Bayesian posterior distributions, Markov chain Monte Carlo (MCMC) algorithms have difficulty moving between modes, and default variational or mode-based approximate inferences will understate posterior…

统计方法学 · 统计学 2021-11-19 Yuling Yao , Aki Vehtari , Andrew Gelman

Datasets are growing not just in size but in complexity, creating a demand for rich models and quantification of uncertainty. Bayesian methods are an excellent fit for this demand, but scaling Bayesian inference is a challenge. In response…

机器学习 · 统计学 2016-03-23 Elaine Angelino , Matthew James Johnson , Ryan P. Adams

The aim of this paper is to discuss both higher-order asymptotic expansions and skewed approximations for the Bayesian Discrepancy Measure for testing precise statistical hypotheses. In particular, we derive results on third-order…

统计方法学 · 统计学 2025-05-02 Elena Bortolato , Francesco Bertolino , Monica Musio , Laura Ventura

In observational studies, unmeasured confounders present a crucial challenge in accurately estimating desired causal effects. To calculate the hazard ratio (HR) in Cox proportional hazard models for time-to-event outcomes, two-stage…

Deep learning has recently revealed the existence of scaling laws, demonstrating that model performance follows predictable trends based on dataset and model sizes. Inspired by these findings and fascinating phenomena emerging in the…

机器学习 · 统计学 2026-02-10 Mattia Rosso , Simone Rossi , Giulio Franzese , Markus Heinonen , Maurizio Filippone

Background: Mendelian randomization (MR) is a useful approach to causal inference from observational studies when randomised controlled trials are not feasible. However, study heterogeneity of two association studies required in MR is often…

统计方法学 · 统计学 2021-12-16 Linyi Zou , Hui Guo , Carlo Berzuini

Towards understanding the fundamental limits of estimation from data of varied quality, we study the problem of estimating a mean parameter from heteroskedastic Gaussian observations where the variances are unknown and may vary arbitrarily…

统计理论 · 数学 2026-03-17 Yanjun Han , Abhishek Shetty , Jacob Shkrob

Ordinary differential equations (ODEs) are used to model dynamic systems appearing in engineering, physics, biomedical sciences and many other fields. These equations contain unknown parameters, say $\theta$ of physical significance which…

统计理论 · 数学 2014-03-05 Prithwish Bhaumik , Subhashis Ghosal

Variable selection techniques have become increasingly popular amongst statisticians due to an increased number of regression and classification applications involving high-dimensional data where we expect some predictors to be unimportant.…

统计方法学 · 统计学 2010-09-20 Anthony Lee , Francois Caron , Arnaud Doucet , Chris Holmes

In this paper, we develop a Bayesian multiscale approach based on a multiscale finite element method. Because of scale disparity in many multiscale applications, computational models can not resolve all scales. Various subgrid models are…

数值分析 · 数学 2017-02-13 Y. Efendiev , W. T. Leung , S. W. Cheung , N. Guha , V. H. Hoang , B. Mallick

Data-driven design shows the promise of accelerating materials discovery but is challenging due to the prohibitive cost of searching the vast design space of chemistry, structure, and synthesis methods. Bayesian Optimization (BO) employs…

机器学习 · 统计学 2023-04-12 Hengrui Zhang , Wei Wayne Chen , Akshay Iyer , Daniel W. Apley , Wei Chen

Bayesian optimization (BO) is a sample-efficient approach to optimizing costly-to-evaluate black-box functions. Most BO methods ignore how evaluation costs may vary over the optimization domain. However, these costs can be highly…

机器学习 · 计算机科学 2021-11-15 Raul Astudillo , Daniel R. Jiang , Maximilian Balandat , Eytan Bakshy , Peter I. Frazier

Berliner (Likelihood and Bayesian prediction for chaotic systems, J. Am. Stat. Assoc. 1991) identified a number of difficulties in using the likelihood function within the Bayesian paradigm which arise both for state estimation and for…

数据分析、统计与概率 · 物理学 2016-12-30 Hailiang Du , Leonard A. Smith

In this paper, we address the fundamental problem of line spectral estimation in a Bayesian framework. We target model order and parameter estimation via variational inference in a probabilistic model in which the frequencies are…

信息论 · 计算机科学 2017-04-05 Mihai-Alin Badiu , Thomas Lundgaard Hansen , Bernard Henri Fleury

The availability of data sets with large numbers of variables is rapidly increasing. The effective application of Bayesian variable selection methods for regression with these data sets has proved difficult since available Markov chain…

统计计算 · 统计学 2019-05-08 Jim Griffin , Krys Latuszynski , Mark Steel