中文
相关论文

相关论文: Graph Based Link Prediction between Human Phenotyp…

200 篇论文

Identifying disease-associated genes enables the development of precision medicine and the understanding of biological processes. Genome-wide association studies (GWAS), gene expression data, biological pathway analysis, and protein network…

基因组学 · 定量生物学 2026-03-10 Muhammad Muneeb , David B. Ascher , YooChan Myung

In real-world networks, predicting the weight (strength) of links is as crucial as predicting the existence of the links themselves. Previous studies have primarily used shallow graph features for link weight prediction, limiting the…

社会与信息网络 · 计算机科学 2024-10-29 Jinbi Liang , Cunlai Pu , Xiangbo Shu , Yongxiang Xia , Chengyi Xia

Heterogeneous graph neural networks (GNNs) achieve strong performance on node classification tasks in a semi-supervised learning setting. However, as in the simpler homogeneous GNN case, message-passing-based heterogeneous GNNs may struggle…

机器学习 · 计算机科学 2022-10-24 Hongjoon Ahn , Yongyi Yang , Quan Gan , Taesup Moon , David Wipf

Motivation: Predicting gene-disease associations (GDAs) is the problem to determine which gene is associated with a disease. GDA prediction can be framed as a ranking problem where genes are ranked for a query disease, based on features…

定量方法 · 定量生物学 2026-02-03 Fernando Zhapa-Camacho , Robert Hoehndorf

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

机器学习 · 计算机科学 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

The identification of essential genes/proteins is a critical step towards a better understanding of human biology and pathology. Computational approaches helped to mitigate experimental constraints by exploring machine learning (ML) methods…

分子网络 · 定量生物学 2021-08-02 João Schapke , Anderson Tavares , Mariana Recamonde-Mendoza

Graph embedding learning that aims to automatically learn low-dimensional node representations, has drawn increasing attention in recent years. To date, most recent graph embedding methods are evaluated on social and information networks…

The emerging research shows that lncRNAs are associated with a series of complex human diseases. However, most of the existing methods have limitations in identifying nonlinear lncRNA-disease associations (LDAs), and it remains a huge…

机器学习 · 计算机科学 2024-05-07 Jin-Xing Liu , Wen-Yu Xi , Ling-Yun Dai , Chun-Hou Zheng , Ying-Lian Gao

Social recommendation based on social network has achieved great success in improving the performance of recommendation system. Since social network (user-user relations) and user-item interactions are both naturally represented as…

信息检索 · 计算机科学 2021-09-27 Yiming Zhang , Lingfei Wu , Qi Shen , Yitong Pang , Zhihua Wei , Fangli Xu , Ethan Chang , Bo Long

Recently, graph neural networks (GNNs) have proved to be suitable in tasks on unstructured data. Particularly in tasks as community detection, node classification, and link prediction. However, most GNN models still operate with static…

机器学习 · 计算机科学 2019-06-07 Darwin Saire Pilco , Adín Ramírez Rivera

Discovering human cognitive and emotional states using multi-modal physiological signals draws attention across various research applications. Physiological responses of the human body are influenced by human cognition and commonly used to…

Affordable, high-quality whole-genome assemblies have made it possible to construct rich pangenomes that capture haplotype diversity across many species. As these datasets grow, they motivate the development of specialized techniques…

基因组学 · 定量生物学 2025-12-19 Gorkem Kadir Solun , Ugur Dogrusoz

Inferring missing links or detecting spurious ones based on observed graphs, known as link prediction, is a long-standing challenge in graph data analysis. With the recent advances in deep learning, graph neural networks have been used for…

社会与信息网络 · 计算机科学 2023-01-03 Xingping Xian , Tao Wu , Xiaoke Ma , Shaojie Qiao , Yabin Shao , Chao Wang , Lin Yuan , Yu Wu

Graph neural network (GNN) has gained increasing popularity in recent years owing to its capability and flexibility in modeling complex graph structure data. Among all graph learning methods, hypergraph learning is a technique for exploring…

机器学习 · 计算机科学 2024-12-31 Tiehua Zhang , Yuze Liu , Zhishu Shen , Xingjun Ma , Peng Qi , Zhijun Ding , Jiong Jin

The problem of link prediction, predicting if two nodes in a network have a connection between them, is a theoretical problem with numerous field-agnostic real-world applications. This paper investigates the efficacy of three classes of…

社会与信息网络 · 计算机科学 2023-06-23 Vivian Feng

Motivation: Molecular interaction networks summarize complex biological processes as graphs, whose structure is informative of biological function at multiple scales. Simultaneously, omics technologies measure the variation or activity of…

定量方法 · 定量生物学 2020-12-24 Ramin Hasibi , Tom Michoel

Link prediction is a key aspect of graph machine learning, with applications as diverse as disease prediction, social network recommendations, and drug discovery. It involves predicting new links that may form between network nodes. Despite…

机器学习 · 计算机科学 2023-09-12 Haohui Lu , Shahadat Uddin

Recommender system research has oftentimes focused on approaches that operate on large-scale datasets containing millions of user interactions. However, many small businesses struggle to apply state-of-the-art models due to their very…

Biological and cellular systems are often modeled as graphs in which vertices represent objects of interest (genes, proteins, drugs) and edges represent relational ties among these objects (binds-to, interacts-with, regulates). This…

机器学习 · 统计学 2017-03-16 Jose Lugo-Martinez , Predrag Radivojac

Graph Neural Networks (GNNs) are important across different domains, such as social network analysis and recommendation systems, due to their ability to model complex relational data. This paper introduces subgraph queries as a new task for…

机器学习 · 计算机科学 2024-08-09 Erfaneh Mahmoudzadeh , Parmis Naddaf , Kiarash Zahirnia , Oliver Schulte