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相关论文: Strontium-releasing mesoporous bioactive glasses w…

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Novel materials, based on Mesoporous Bioactive Glasses (MBGs) in the ternary system SiO2-CaO-P2O5, decorated with (3-aminopropyl)triethoxysilane (APTES) and subsequently with amino acid Lysine (Lys), by post-grafting method on the external…

组织与器官 · 定量生物学 2021-04-23 S Sanchez-Salcedo , A Garcia , M Vallet-Regi

A mesoporous bioactive glass (MBG) of molar composition 75SiO2-20CaO-5P2O5 (MBG-75S) has been synthetized as a potential bioceramic for bone regeneration purposes. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR),…

组织与器官 · 定量生物学 2021-03-16 N. Gomez-Cerezo , L. Casarrubios , I. Morales , M. J. Feito , M. Vallet-Regi , D. Arcos , M. T. Portoles

There is an urgent need of biosynthetic bone grafts with enhanced osteogenic capacity. In this study, we describe the design of hierarchical meso-macroporous 3D-scaffolds based on mesoporous bioactive glasses (MBGs), enriched with the…

生物大分子 · 定量生物学 2021-03-26 C. Heras , S. Sanchez-Salcedo , D. Lozano , J. Peña , P. Esbrit , M. Vallet-Regi , A. J. Salinas

Mesoporous bioactive glasses, MBG, are gaining increasing interest in the design of new biomaterials for bone defects treatment. An important research trend to enhance their biological behavior is the inclusion of moderate amounts of oxides…

定量方法 · 定量生物学 2021-03-23 J Jimenez-Holguin , S Sanchez-Salcedo , M Vallet-Regi , A J Salinas

Mesoporous bioactive glasses (MBGs) in the system SiO2-CaO-P2O5-Ga2O3 have been synthesized by the evaporation induced self-assembly method and subsequent impregnation with Ga cations. Two different compositions have been prepared and the…

组织与器官 · 定量生物学 2021-03-23 N. Gomez-Cerezo , E. Verron , V. Montouillout , F. Fayon , P. Lagadec , J. M. Bouler , B. Bujoli , D. Arcos , M. Vallet-Regi

Mesoporous bioactive glasses (MBGs) are bioceramics designed to induce bone tissue regeneration and very useful materials with the ability to act as drug delivery systems. MBGs can be implanted in contact with bone tissue in different ways,…

A very small number of biomaterials investigated for bone regeneration was reported as able to prevent the oxidative stress. In this study beads based on alginate hydrogel and mesoporous glasses (MG) containing different amounts of cerium…

组织与器官 · 定量生物学 2021-05-24 E. Varini , S. Sanchez-Salcedo , G. Malavasi , G. Lusvardi , M. Vallet-Regi , A. J. Salinas

Macroporous scaffolds made of a SiO2-CaO-P2O5 mesoporous bioactive glass (MBG) and epolycaprolactone (PCL) have been prepared by robocasting. These scaffolds showed an excellent in vitro biocompatibility in contact with osteoblast like…

Silica mesoporous nanomaterials have been proved to have meaningful application in biotechnology and biomedicine. Particularly, mesoporous bioactive glasses are recently gaining importance thanks to their bone regenerative properties.…

组织与器官 · 定量生物学 2021-03-19 L Polo , N Gomez-Cerezo , E Aznar , JL Vivancos , F Sancenon , D Arcos , M Vallet-Regi , R Martinez-Manez

Three-dimensional Mesoporous bioactive glasses (MBGs) scaffolds has been widely considered for bone regeneration purposes and additive manufacturing enables the fabrication of highly bioactive patient-specific constructs for bone defects.…

组织与器官 · 定量生物学 2021-03-23 M. Natividad Gomez-Cerezo , Daniel Lozano , Daniel Arcos , Maria Vallet-Regi , Cedryck Vaquette

Bone regeneration is a clinical challenge that requires multiple approaches. Sometimes, it also includes the development of new osteogenic and antibacterial biomaterials to treat the occurrence of possible infection processes derived from…

定量方法 · 定量生物学 2021-03-24 C. Heras , J. Jimenez Holguin , A. L. Doadrio , M. Vallet-Regi , S. Sanchez-Salcedo , A. J. Salinas

The regeneration of oral and craniofacial bone defects ranging from minor periodontal and peri-implant defects to large and critical lesions imposes a substantial global health burden. Conventional therapies are associated with several…

The osteoinductive property of strontium was repeatedly proven in the last decades. Compelling $\textit{in vitro}$ data demonstrated that strontium hydroxyapatite nanoparticles exert a dual action, by promoting osteoblasts-driven matrix…

In this manuscript, we propose a simple and versatile methodology to design nanosystems based on biocompatible and multicomponent mesoporous silica nanoparticles (MSNs) for infection management. This strategy relies on the combination of…

The design of drug delivery systems needs to consider biocompatibility and host body recognition for an adequate actuation. In this work, mesoporous silica nanoparticles (MSNs) surfaces were successfully modified with two silane molecules…

Magnesium (Mg) and its alloys have attracted considerable attention owing to their excellent biodegradable properties and biocompatibility. Novel Mg-Sn-Ge ternary Mg alloys were developed as potential biodegradable materials for orthopedic…

医学物理 · 物理学 2022-12-21 Xian Wei , Sujie Ma , Jiajia Meng , Hong Qing , Qing Zhao

Certain biomaterials are capable of inducing the secretion of Vascular Endothelial Growth Factor (VEGF) from cells exposed to their biochemical influence, which plays a vital role in stimulating angiogenesis. Looking for this capacity, in…

Achieving an optimal biomechanical environment within bone scaffolds is critical for promoting tissue regeneration, particularly in load-bearing anatomical sites where rigid fixation can induce stress shielding and compromise healing.…

A novel multifunctional nanodevice based in doxorubicin (DOX)- loaded mesoporous silica nanoparticles (MSNs) as nanoplatforms for the assembly of different building blocks has been developed for bone cancer treatment. These building blocks…

组织与器官 · 定量生物学 2021-03-19 M. Martinez-Carmona , D. Lozano , M. Colilla , M. Vallet-Regi

In order to increase the bone forming ability of MBG-PCL composite scaffold, microporosity was created in the struts of 3D-printed MBG-PCL scaffolds for the manufacturing of a construct with a multiscale porosity consisting of meso-, micro-…

组织与器官 · 定量生物学 2021-04-06 M. Natividad Gomez-Cerezo , Juan Pena , Saso Ivanovski , Daniel Arcos , Maria Vallet-Regi , Cedryck Vaquette
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