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In many clinical trials, outcomes of interest include binary-valued endpoints. It is not uncommon that a binary-valued outcome is dichotomized from a continuous outcome at a threshold of clinical interest. To reach the objective, common…

应用统计 · 统计学 2021-08-05 Chenchen Ma , Xin Shen , Yongming Qu , Yu Du

This paper develops new methods for causal inference in observational studies on a single large network of interconnected units, addressing two key challenges: long-range dependence among units and the presence of general interference. We…

统计方法学 · 统计学 2025-11-24 Jizhou Liu , Dake Zhang , Eric J. Tchetgen Tchetgen

Clinicians prescribe antibiotics by looking at the patient's health record with an experienced eye. However, the therapy might be rendered futile if the patient has drug resistance. Determining drug resistance requires time-consuming…

人工智能 · 计算机科学 2023-03-09 Honglin Shu , Pei Gao , Lingwei Zhu , Zheng Chen

There is a lack of methodological results for continuous time change detection due to the challenges of noninformative prior specification and efficient posterior inference in this setting. Most methodologies to date assume data are…

统计方法学 · 统计学 2025-04-28 Dan Cunha , Mark Friedl , Luis Carvalho

Recently, there as been an increasing interest in the use of heavily restricted randomization designs which enforces balance on observed covariates in randomized controlled trials. However, when restrictions are strict, there is a risk that…

统计方法学 · 统计学 2021-10-15 Mattias Nordin , Mårten Schultzberg

In Markov Decision Processes (MDPs) with intermittent state information, decision-making becomes challenging due to periods of missing observations. Linear programming (LP) methods can play a crucial role in solving MDPs, in particular,…

最优化与控制 · 数学 2025-09-09 Konstantin Avrachenkov , Madhu Dhiman , Veeraruna Kavitha

Panel count data arise in clinical trials when patients are asked to report their occurrences of events of interest periodically but the exact event times are unknown, only the count of events between two successive examinations are…

统计方法学 · 统计学 2025-05-29 Jiangjie Zhou , Baosheng Liang

Observational studies provide invaluable opportunities to draw causal inference, but they may suffer from biases due to pretreatment difference between treated and control units. Matching is a popular approach to reduce observed covariate…

统计方法学 · 统计学 2025-09-17 Xinran Li

We develop a novel class of MCMC algorithms based on a stochastized Nesterov scheme. With an appropriate addition of noise, the result is a time-inhomogeneous underdamped Langevin equation, which we prove emits a specified target…

计算工程、金融与科学 · 计算机科学 2023-11-29 Duy H. Thai , Alexander L. Young , David B. Dunson

In this paper, we consider binary response models with linear quantile restrictions. Considerably generalizing previous research on this topic, our analysis focuses on an infinite collection of quantile estimators. We derive a uniform…

统计方法学 · 统计学 2020-03-25 Stanislav Volgushev

We propose a distributionally robust return-risk model for Markov decision processes (MDPs) under risk and reward ambiguity. The proposed model optimizes the weighted average of mean and percentile performances, and it covers the…

机器学习 · 计算机科学 2023-01-05 Haolin Ruan , Zhi Chen , Chin Pang Ho

In observational studies, the identification of causal estimands depends on the no unmeasured confounding (NUC) assumption. As this assumption is not testable from observed data, sensitivity analysis plays an important role in observational…

统计方法学 · 统计学 2023-09-28 Md Abdul Basit , Mahbub A. H. M. Latif , Abdus S Wahed

This monograph develops a comprehensive statistical learning framework that is robust to (distributional) perturbations in the data using Distributionally Robust Optimization (DRO) under the Wasserstein metric. Beginning with fundamental…

机器学习 · 统计学 2021-08-23 Ruidi Chen , Ioannis Ch. Paschalidis

In this paper we propose an output-feedback Model Predictive Control (MPC) algorithm for linear discrete-time systems affected by a possibly unbounded additive noise and subject to probabilistic constraints. In case the noise distribution…

系统与控制 · 计算机科学 2014-08-29 Marcello Farina , Luca Giulioni , Lalo Magni , Riccardo Scattolini

In offline reinforcement learning (RL), the absence of active exploration calls for attention on the model robustness to tackle the sim-to-real gap, where the discrepancy between the simulated and deployed environments can significantly…

机器学习 · 计算机科学 2024-06-28 He Wang , Laixi Shi , Yuejie Chi

The goal of causal mediation analysis, often described within the potential outcomes framework, is to decompose the effect of an exposure on an outcome of interest along different causal pathways. Using the assumption of sequential…

统计方法学 · 统计学 2021-11-09 Lexi Rene , Antonio R. Linero , Elizabeth Slate

Irregular multivariate time series with missing values present significant challenges for predictive modeling in domains such as healthcare. While deep learning approaches often focus on temporal interpolation or complex architectures to…

机器学习 · 计算机科学 2026-03-16 Dingyi Nie , Yixing Wu , C. -C. Jay Kuo

We introduce a linear-scaling stochastic method to compute real-space maps of any positive local spectral operator in a tight-binding model. By employing positive-definite estimators, the sampling error at each site can be rigorously…

无序系统与神经网络 · 物理学 2025-11-18 H. P. Veiga , D. R. Pinheiro , J. P. Santos Pires , J. M. Viana Parente Lopes

Standard random-effects meta-analysis relies heavily on the assumption that the underlying true effects are normally distributed. In the social sciences, where evidence synthesis increasingly involves large, highly heterogeneous datasets,…

统计方法学 · 统计学 2026-05-01 Daihe Sui , Elizabeth Tipton

This paper studies the estimation of network weights for a class of systems with binary-valued observations. In these systems only quantized observations are available for the network estimation. Furthermore, system states are coupled with…

系统与控制 · 计算机科学 2019-03-19 Yu Xing , Xingkang He , Haitao Fang , Karl Henrik Johansson