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Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide…

Novel digital data sources and tools like machine learning (ML) and artificial intelligence (AI) have the potential to revolutionize data about development and can contribute to monitoring and mitigating humanitarian problems. The potential…

In recent years, machine learning has demonstrated impressive results in various fields, including software vulnerability detection. Nonetheless, using machine learning to identify software vulnerabilities presents new challenges,…

密码学与安全 · 计算机科学 2025-08-22 Sima Arasteh , Christophe Hauser

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

图像与视频处理 · 电气工程与系统科学 2022-10-24 Solene Bechelli

The advent of quantum computing has opened new possibilities in data science, offering unique capabilities for addressing complex, data-intensive problems. Traditional machine learning algorithms often face challenges in high-dimensional or…

量子物理 · 物理学 2025-02-13 Sanjeev Naguleswaran

Generative AI has had a profound impact on biomedicine and health, both in professional work and in education. Based on large language models (LLMs), generative AI has been found to perform as well as humans in simulated situations taking…

人工智能 · 计算机科学 2025-01-20 William Hersh

Diabetes is a worldwide health issue affecting millions of people. Machine learning methods have shown promising results in improving diabetes prediction, particularly through the analysis of diverse data types, namely gene expression data.…

机器学习 · 计算机科学 2024-04-24 Rita T. Sousa , Heiko Paulheim

Robotic technology has the potential to revolutionize the field of neurology by providing new methods for diagnosis, treatment, and rehabilitation of neurological disorders. In recent years, there has been an increasing interest in the…

This report explores the application of machine learning techniques on short timeseries gene expression data. Although standard machine learning algorithms work well on longer time-series', they often fail to find meaningful insights from…

基因组学 · 定量生物学 2021-11-17 Akankshita Dash

Protein engineering seeks to identify protein sequences with optimized properties. When guided by machine learning, protein sequence generation methods can draw on prior knowledge and experimental efforts to improve this process. In this…

定量方法 · 定量生物学 2021-05-28 Zachary Wu , Kadina E. Johnston , Frances H. Arnold , Kevin K. Yang

Background: Electronic Health Records (EHRs) contain rich information of patients' health history, which usually include both structured and unstructured data. There have been many studies focusing on distilling valuable information from…

机器学习 · 计算机科学 2021-11-10 Ziyi Liu , Jiaqi Zhang , Yongshuai Hou , Xinran Zhang , Ge Li , Yang Xiang

Identification of disease genes, which are a set of genes associated with a disease, plays an important role in understanding and curing diseases. In this paper, we present a biomedical knowledge graph designed specifically for this…

Genomic alterations lead to cancer complexity and form a major hurdle for a comprehensive understanding of the molecular mechanisms underlying oncogenesis. In this review, we describe the recent advances in studying cancer-associated genes…

分子网络 · 定量生物学 2007-12-24 Edwin Wang , Anne Lenferink , Maureen O'Connor-McCourt

This paper presents a comprehensive systematic review of generative models (GANs, VAEs, DMs, and LLMs) used to synthesize various medical data types, including imaging (dermoscopic, mammographic, ultrasound, CT, MRI, and X-ray), text,…

Deep learning is transforming many areas in science, and it has great potential in modeling molecular systems. However, unlike the mature deployment of deep learning in computer vision and natural language processing, its development in…

计算物理 · 物理学 2021-03-19 Jun Zhang , Yao-Kun Lei , Zhen Zhang , Junhan Chang , Maodong Li , Xu Han , Lijiang Yang , Yi Isaac Yang , Yi Qin Gao

Context: Machine learning (ML) may enable effective automated test generation. Objective: We characterize emerging research, examining testing practices, researcher goals, ML techniques applied, evaluation, and challenges. Methods: We…

软件工程 · 计算机科学 2023-04-18 Afonso Fontes , Gregory Gay

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

基因组学 · 定量生物学 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Recent years have seen tremendous developments in the use of machine learning models to link amino acid sequence, structure and function of folded proteins. These methods are, however, rarely applicable to the wide range of proteins and…

生物大分子 · 定量生物学 2025-02-27 Sören von Bülow , Giulio Tesei , Kresten Lindorff-Larsen

Medical Informatics and the application of modern signal processing in the assistance of the diagnostic process in medical imaging is one of the more recent and active research areas today. This thesis addresses a variety of issues related…

计算机视觉与模式识别 · 计算机科学 2009-10-20 Harris Georgiou

Machine learning (ML) is a subfield of Artificial intelligence (AI), and its applications in radiology are growing at an ever-accelerating rate. The most studied ML application is the automated interpretation of images. However, natural…

计算机视觉与模式识别 · 计算机科学 2022-06-24 Nihal Raju , Michael Woodburn , Stefan Kachel , Jack O'Shaughnessy , Laurence Sorace , Natalie Yang , Ruth P Lim
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