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Multimodal positron emission tomography-computed tomography (PET-CT) is used routinely in the assessment of cancer. PET-CT combines the high sensitivity for tumor detection with PET and anatomical information from CT. Tumor segmentation is…

图像与视频处理 · 电气工程与系统科学 2022-06-13 Xiaohang Fu , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

In concurrent chemoradiotherapy, chemotherapeutic agents are administered during the course of radiotherapy to enhance the primary tumor control. However, that often comes at the expense of increased risk of normal-tissue complications. The…

医学物理 · 物理学 2014-12-12 Ehsan Salari , Jan Unkelbach , Thomas Bortfeld

Abdominal organ and tumour segmentation has many important clinical applications, such as organ quantification, surgical planning, and disease diagnosis. However, manual assessment is inherently subjective with considerable inter- and…

图像与视频处理 · 电气工程与系统科学 2023-11-17 Wentao Liu , Tong Tian , Weijin Xu , Lemeng Wang , Haoyuan Li , Huihua Yang

Deep learning has facilitated the automation of radiotherapy by predicting accurate dose distribution maps. However, existing methods fail to derive the desirable radiotherapy parameters that can be directly input into the treatment…

计算机视觉与模式识别 · 计算机科学 2024-03-01 Jiaqi Cui , Yuanyuan Xu , Jianghong Xiao , Yuchen Fei , Jiliu Zhou , Xingcheng Peng , Yan Wang

Radiotherapy (RT) is a key component in the treatment of various cancers, including Acute Lymphocytic Leukemia (ALL) and Acute Myelogenous Leukemia (AML). Precise delineation of organs at risk (OARs) and target areas is essential for…

计算机视觉与模式识别 · 计算机科学 2023-11-14 Ricardo Coimbra Brioso , Damiano Dei , Ciro Franzese , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

In industrial X-ray Computed Tomography (CT), the need for rapid in-line inspection is critical. Sparse-angle tomography plays a significant role in this by reducing the required number of projections, thereby accelerating processing and…

计算机视觉与模式识别 · 计算机科学 2025-05-27 Tianyuan Wang , Felix Lucka , Daniël M. Pelt , K. Joost Batenburg , Tristan van Leeuwen

Bayesian Optimisation (BO) is a state-of-the-art global optimisation technique for black-box problems where derivative information is unavailable, and sample efficiency is crucial. However, improving the general scalability of BO has proved…

最优化与控制 · 数学 2024-12-13 Luo Long , Coralia Cartis , Paz Fink Shustin

Multi-objective optimization (MOO) has become an influential framework in many machine learning problems with multiple objectives such as learning with multiple criteria and multi-task learning (MTL). In this paper, we propose a new…

机器学习 · 计算机科学 2023-11-30 Peiyao Xiao , Hao Ban , Kaiyi Ji

Prostate radiotherapy is a well established curative oncology modality, which in future will use Magnetic Resonance Imaging (MRI)-based radiotherapy for daily adaptive radiotherapy target definition. However the time needed to delineate the…

图像与视频处理 · 电气工程与系统科学 2020-11-17 David Gillespie , Connah Kendrick , Ian Boon , Cheng Boon , Tim Rattay , Moi Hoon Yap

In intensity-modulated radiation therapy, optimal intensity distributions of incoming beams are decomposed into linear combinations of leaf openings of a multileaf collimator (segments). In order to avoid inefficient dose delivery, the…

医学物理 · 物理学 2010-09-29 Antje Kiesel , Tobias Gauer

Existing state-of-the-art methods for surgical phase recognition either rely on the extraction of spatial-temporal features at a short-range temporal resolution or adopt the sequential extraction of the spatial and temporal features across…

计算机视觉与模式识别 · 计算机科学 2024-08-08 Shu Yang , Luyang Luo , Qiong Wang , Hao Chen

Performing a real-time and accurate instrument segmentation from videos is of great significance for improving the performance of robotic-assisted surgery. We identify two important clues for surgical instrument perception, including local…

计算机视觉与模式识别 · 计算机科学 2021-09-29 Jiacheng Wang , Yueming Jin , Liansheng Wang , Shuntian Cai , Pheng-Ann Heng , Jing Qin

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

医学物理 · 物理学 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

We consider a two-stage stochastic optimization problem, in which a long-term optimization variable is coupled with a set of short-term optimization variables in both objective and constraint functions. Despite that two-stage stochastic…

最优化与控制 · 数学 2021-07-07 An Liu , Rui Yang , Tony Q. S. Quek , Min-Jian Zhao

The idea of iterative process optimization based on collected output measurements, or "real-time optimization" (RTO), has gained much prominence in recent decades, with many RTO algorithms being proposed, researched, and developed. While…

最优化与控制 · 数学 2013-08-14 Gene A. Bunin , Grégory François , Dominique Bonvin

Bayesian optimisation (BO) is a standard approach for sample-efficient global optimisation of expensive black-box functions, yet its scalability to high dimensions remains challenging. Here, we investigate nonlinear dimensionality reduction…

最优化与控制 · 数学 2025-10-20 Luo Long , Coralia Cartis , Paz Fink Shustin

Background: Ultra-high-dose-rate (UHDR) radiation therapy has demonstrated promising potential in reducing toxicity to organs-at-risk (OARs). Proton therapy is uniquely positioned to deliver UHDR by leveraging the Bragg peak in conjunction…

医学物理 · 物理学 2025-04-30 Jiayue Han , Ya-Nan Zhu , Aoxiang Wang , Wangyao Li , Yuting Lin , Hao Gao

In radiation therapy (RT) treatment planning, multi-criteria optimization (MCO) supports efficient plan selection but is usually solved for population-based dosimetric criteria and ignores patient-specific biological risk, potentially…

医学物理 · 物理学 2026-01-09 Mara Schubert , Katrin Teichert , Zhongxing Liao , Thomas Bortfeld , Ali Ajdari

We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…

医学物理 · 物理学 2019-12-23 Azar Sadeghnejad Barkousaraie , Olalekan Ogunmolu , Steve Jiang , Dan Nguyen

Conventional beam orientation optimization (BOO) algorithms for IMRT assume that the same set of beam angles is used for all treatment fractions. In this paper we present a BOO formulation based on group sparsity that simultaneously…

医学物理 · 物理学 2018-03-14 Daniel O'Connor , Dan Nguyen , Dan Ruan , Victoria Yu , Ke Sheng