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Randomized trials typically estimate average relative treatment effects, but decisions on the benefit of a treatment are possibly better informed by more individualized predictions of the absolute treatment effect. In case of a binary…

统计方法学 · 统计学 2021-08-20 J Hoogland , J IntHout , M Belias , MM Rovers , RD Riley , FE Harrell , KGM Moons , TPA Debray , JB Reitsma

We study the problem of deriving policies, or rules, that when enacted on a complex system, cause a desired outcome. Absent the ability to perform controlled experiments, such rules have to be inferred from past observations of the system's…

机器学习 · 计算机科学 2020-09-09 Kailash Budhathoki , Mario Boley , Jilles Vreeken

Practitioners in diverse fields such as healthcare, economics and education are eager to apply machine learning to improve decision making. The cost and impracticality of performing experiments and a recent monumental increase in electronic…

机器学习 · 计算机科学 2023-08-01 Fredrik D. Johansson , Uri Shalit , Nathan Kallus , David Sontag

Classical causal and statistical inference methods typically assume the observed data consists of independent realizations. However, in many applications this assumption is inappropriate due to a network of dependences between units in the…

机器学习 · 计算机科学 2019-07-02 Rohit Bhattacharya , Daniel Malinsky , Ilya Shpitser

Randomized Controlled Trials are one of the pillars of science; nevertheless, they rely on hand-crafted hypotheses and expensive analysis. Such constraints prevent causal effect estimation at scale, potentially anchoring on popular yet…

机器学习 · 计算机科学 2026-01-07 Tommaso Mencattini , Riccardo Cadei , Francesco Locatello

The causal effect of an intervention (treatment/exposure) on an outcome can be estimated by: i) specifying knowledge about the data-generating process; ii) assessing under what assumptions a target quantity, such as for example a causal…

统计方法学 · 统计学 2021-03-05 Michael Schomaker

Understanding causal mechanisms across different populations is essential for designing effective public health interventions. Recently, difference graphs have been introduced as a tool to visually represent causal variations between two…

人工智能 · 计算机科学 2025-02-18 Charles K. Assaad

Individual treatment effects are not point-identified from data. The Probability of Necessity and Sufficiency (PNS) circumvents this limitation by characterizing individual-level causality through intersection bounds derived from combined…

机器学习 · 统计学 2026-05-11 Gandharv Patil , Keyi Tang , Raquel Aoki , Leo Guelman

Estimating the Individual Treatment Effect from observational data, defined as the difference between outcomes with and without treatment or intervention, while observing just one of both, is a challenging problems in causal learning. In…

机器学习 · 计算机科学 2020-05-07 Céline Beji , Michaël Bon , Florian Yger , Jamal Atif

There is intense interest in applying machine learning to problems of causal inference in fields such as healthcare, economics and education. In particular, individual-level causal inference has important applications such as precision…

机器学习 · 统计学 2017-05-17 Uri Shalit , Fredrik D. Johansson , David Sontag

We investigate the task of estimating the conditional average causal effect of treatment-dosage pairs from a combination of observational data and assumptions on the causal relationships in the underlying system. This has been a…

机器学习 · 计算机科学 2022-05-31 Alexis Bellot , Anish Dhir , Giulia Prando

We propose a novel approach for inferring the individualized causal effects of a treatment (intervention) from observational data. Our approach conceptualizes causal inference as a multitask learning problem; we model a subject's potential…

机器学习 · 计算机科学 2017-06-20 Ahmed M. Alaa , Michael Weisz , Mihaela van der Schaar

Although the existing causal inference literature focuses on the forward-looking perspective by estimating effects of causes, the backward-looking perspective can provide insights into causes of effects. In backward-looking causal…

统计理论 · 数学 2025-08-26 Chao Zhang , Zhi Geng , Wei Li , Peng Ding

We address the problem of integrating data from multiple, possibly biased, observational and interventional studies, to eventually compute counterfactuals in structural causal models. We start from the case of a single observational dataset…

人工智能 · 计算机科学 2023-03-17 Marco Zaffalon , Alessandro Antonucci , David Huber , Rafael Cabañas

When making treatment selection decisions, it is essential to include a causal effect estimation analysis to compare potential outcomes under different treatments or controls, assisting in optimal selection. However, merely estimating…

机器学习 · 统计学 2024-10-08 Sherly Alfonso-Sánchez , Kristina P. Sendova , Cristián Bravo

Assessing the effects of a policy based on observational data from a different policy is a common problem across several high-stake decision-making domains, and several off-policy evaluation (OPE) techniques have been proposed. However,…

机器学习 · 计算机科学 2022-01-21 Sonali Parbhoo , Shalmali Joshi , Finale Doshi-Velez

Recent approaches in causal inference have proposed estimating average causal effects that are local to some subpopulation, often for reasons of efficiency. These inferential targets are sometimes data-adaptive, in that they are dependent…

统计理论 · 数学 2016-02-08 Peter M. Aronow

Causal models communicate our assumptions about causes and effects in real-world phe- nomena. Often the interest lies in the identification of the effect of an action which means deriving an expression from the observed probability…

机器学习 · 统计学 2018-06-20 Santtu Tikka , Juha Karvanen

This paper develops a finite population framework for analyzing causal effects in settings with imperfect compliance where multiple treatments affect the outcome of interest. Two prominent examples are factorial designs and panel…

统计方法学 · 统计学 2026-01-26 Pedro Picchetti

Outcome-dependent sampling designs are common in many different scientific fields including epidemiology, ecology, and economics. As with all observational studies, such designs often suffer from unmeasured confounding, which generally…

统计方法学 · 统计学 2020-10-13 Erin E. Gabriel , Michael C. Sachs , Arvid Sjölander