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Peptide receptor radionuclide therapy (PRRT) is an established treatment for metastatic neuroendocrine tumors (NETs), yet long-term disease control occurs only in a subset of patients. Predicting progression-free survival (PFS) could…
The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…
Risk stratification of lung nodules is a task of primary importance in lung cancer diagnosis. Any improvement in robust and accurate nodule characterization can assist in identifying cancer stage, prognosis, and improving treatment…
Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…
Osteosarcoma (OS) is an aggressive primary bone malignancy. Accurate histopathological assessment of viable versus non-viable tumor regions after neoadjuvant chemotherapy is critical for prognosis and treatment planning, yet manual…
Recently, deep learning (DL)-based methods for the generation of synthetic computed tomography (sCT) have received significant research attention as an alternative to classical ones. We present here a systematic review of these methods by…
While we once thought of cancer as single monolithic diseases affecting a specific organ site, we now understand that there are many subtypes of cancer defined by unique patterns of gene mutations. These gene mutational data, which can be…
Despite the advances in medicine, cancer has remained a formidable challenge. Particularly in the case of pancreatic tumors, characterized by their diversity and late diagnosis, early detection poses a significant challenge crucial for…
Neurofibromatosis type 1 (NF1) is an autosomal dominant tumor predisposition syndrome that involves the central and peripheral nervous systems. Accurate detection and segmentation of neurofibromas are essential for assessing tumor burden…
Uncontrolled cell division in the brain is what gives rise to brain tumors. If the tumor size increases by more than half, there is little hope for the patient's recovery. This emphasizes the need of rapid and precise brain tumor diagnosis.…
Invasive ductal carcinoma is a prevalent, potentially deadly disease associated with a high rate of morbidity and mortality. Its malignancy is the second leading cause of death from cancer in women. The mammogram is an extremely useful…
Positron Emission Tomography (PET) is an important clinical imaging tool but inevitably introduces radiation hazards to patients and healthcare providers. Reducing the tracer injection dose and eliminating the CT acquisition for attenuation…
In this paper, we present a fully automatic brain tumor segmentation method based on Deep Neural Networks (DNNs). The proposed networks are tailored to glioblastomas (both low and high grade) pictured in MR images. By their very nature,…
Radiotherapy is one of the primary treatment methods for tumors, but the organ movement caused by respiration limits its accuracy. Recently, 3D imaging from a single X-ray projection has received extensive attention as a promising approach…
Computed Tomography (CT) is a widely utilized imaging modality in clinical settings. Using densely acquired rotational X-ray arrays, CT can capture 3D spatial features. However, it is confronted with challenged such as significant time…
Differentiating tumor progression (TP) from treatment-related necrosis (TN) is critical for clinical management decisions in glioblastoma (GBM). Dynamic FDG PET (dPET), an advance from traditional static FDG PET, may prove advantageous in…
Deep learning for regression tasks on medical imaging data has shown promising results. However, compared to other approaches, their power is strongly linked to the dataset size. In this study, we evaluate 3D-convolutional neural networks…
Statistical shape modeling is an important tool to characterize variation in anatomical morphology. Typical shapes of interest are measured using 3D imaging and a subsequent pipeline of registration, segmentation, and some extraction of…
Accurate delineation of the intraprostatic gross tumour volume (GTV) is a prerequisite for treatment approaches in patients with primary prostate cancer (PCa). Prostate-specific membrane antigen positron emission tomography (PSMA-PET) may…
In this study, an automated three dimensional (3D) deep segmentation approach for detecting gliomas in 3D pre-operative MRI scans is proposed. Then, a classi-fication algorithm based on random forests, for survival prediction is presented.…