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An important part of breast cancer staging is the assessment of the sentinel axillary node for early signs of tumor spreading. However, this assessment by pathologists is not always easy and retrospective surveys often requalify the status…

定量方法 · 定量生物学 2024-04-30 Eric Bonnet

Being the most commonly known neurodegeneration, Alzheimer's Disease (AD) is annually diagnosed in millions of patients. The present medical scenario still finds the exact diagnosis and classification of AD through neuroimaging data as a…

图像与视频处理 · 电气工程与系统科学 2025-03-19 Shravan Venkatraman , Pandiyaraju V , Abeshek A , Pavan Kumar S , Aravintakshan S A

The specificty and sensitivity of resting state functional MRI (rs-fMRI) measurements depend on pre-processing choices, such as the parcellation scheme used to define regions of interest (ROIs). In this study, we critically evaluate the…

计算机视觉与模式识别 · 计算机科学 2019-06-06 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert R. Sabuncu

Brain tumors pose a significant global health challenge due to their high prevalence and mortality rates across all age groups. Detecting brain tumors at an early stage is crucial for effective treatment and patient outcomes. This study…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Jonayet Miah , Duc M Cao , Md Abu Sayed3 , Md Siam Taluckder , Md Sabbirul Haque , Fuad Mahmud

This paper considers the task of thorax disease classification on chest X-ray images. Existing methods generally use the global image as input for network learning. Such a strategy is limited in two aspects. 1) A thorax disease usually…

计算机视觉与模式识别 · 计算机科学 2018-01-31 Qingji Guan , Yaping Huang , Zhun Zhong , Zhedong Zheng , Liang Zheng , Yi Yang

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

神经元与认知 · 定量生物学 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Convolutional neural networks (CNNs) are similar to "ordinary" neural networks in the sense that they are made up of hidden layers consisting of neurons with "learnable" parameters. These neurons receive inputs, performs a dot product, and…

计算机视觉与模式识别 · 计算机科学 2019-02-08 Abien Fred Agarap

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

计算机视觉与模式识别 · 计算机科学 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

We propose an interpretable 3D Grid-Attention deep neural network that can accurately predict a person's age and whether they have Alzheimer's disease (AD) from a structural brain MRI scan. Building on a 3D convolutional neural network, we…

组织与器官 · 定量生物学 2020-11-19 Pradeep Lam , Alyssa H. Zhu , Iyad Ba Gari , Neda Jahanshad , Paul M. Thompson

Stacking excessive layers in DNN results in highly underdetermined system when training samples are limited, which is very common in medical applications. In this regard, we present a framework capable of deriving an efficient…

机器学习 · 计算机科学 2025-03-04 Seunghun Baek , Injun Choi , Mustafa Dere , Minjeong Kim , Guorong Wu , Won Hwa Kim

Structural magnetic resonance imaging (sMRI) combined with deep learning has achieved remarkable progress in the prediction and diagnosis of Alzheimer's disease (AD). Existing studies have used CNN and transformer to build a well-performing…

计算机视觉与模式识别 · 计算机科学 2025-09-11 Zheng Yang , Yanteng Zhang , Xupeng Kou , Yang Liu , Chao Ren

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

神经元与认知 · 定量生物学 2025-12-30 Ashley Chen

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

神经元与认知 · 定量生物学 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Saliency maps have been widely used to interpret deep learning classifiers for Alzheimer's disease (AD). However, since AD is heterogeneous and has multiple subtypes, the pathological mechanism of AD remains not fully understood and may…

计算机视觉与模式识别 · 计算机科学 2024-07-12 Yihan Zhang , Xuanshuo Zhang , Wei Wu , Haohan Wang

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

机器学习 · 计算机科学 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

The study's objective is to explore the distinctions in the functional brain network connectivity between Alzheimer's Disease (AD) patients and normal controls using Functional Magnetic Resonance Imaging (fMRI). The study included 590…

神经元与认知 · 定量生物学 2023-05-17 Yongcheng Yao

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

计算机视觉与模式识别 · 计算机科学 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This…

The deviation between chronological age and biological age is a well-recognized biomarker associated with cognitive decline and neurodegeneration. Age-related and pathology-driven changes to brain structure are captured by various…

机器学习 · 计算机科学 2022-11-01 Saurabh Sihag , Gonzalo Mateos , Corey McMillan , Alejandro Ribeiro

Functional Magnetic Resonance Imaging (fMRI) is commonly utilized to study human brain activity, including abnormal functional properties related to neurodegenerative diseases. This study aims to investigate the differences in the…

神经元与认知 · 定量生物学 2023-05-17 Yongcheng Yao