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The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

Energy-based language models (ELMs) parameterize an unnormalized distribution for natural sentences and are radically different from popular autoregressive language models (ALMs). As an important application, ELMs have been successfully…

计算与语言 · 计算机科学 2023-05-30 Hong Liu , Zhaobiao Lv , Zhijian Ou , Wenbo Zhao , Qing Xiao

Entities lie in the heart of biomedical natural language understanding, and the biomedical entity linking (EL) task remains challenging due to the fine-grained and diversiform concept names. Generative methods achieve remarkable…

计算与语言 · 计算机科学 2022-05-24 Hongyi Yuan , Zheng Yuan , Sheng Yu

Existing pre-trained language models (PLMs) have demonstrated the effectiveness of self-supervised learning for a broad range of natural language processing (NLP) tasks. However, most of them are not explicitly aware of domain-specific…

计算与语言 · 计算机科学 2021-09-28 Song Xu , Haoran Li , Peng Yuan , Yujia Wang , Youzheng Wu , Xiaodong He , Ying Liu , Bowen Zhou

The goal of personalized medicine is to discover a treatment regimen that optimizes a patient's clinical outcome based on their personal genetic and environmental factors. However, candidate treatments cannot be arbitrarily administered to…

机器学习 · 计算机科学 2026-02-09 Michael S. Yao , Osbert Bastani , Alma Andersson , Tommaso Biancalani , Aïcha Bentaieb , Claudia Iriondo

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Large language models (LLMs) acquire a breadth of information across various domains. However, their computational complexity, cost, and lack of transparency often hinder their direct application for predictive tasks where privacy and…

机器学习 · 计算机科学 2025-05-29 Alexander Capstick , Rahul G. Krishnan , Payam Barnaghi

The biomedical field relies heavily on concept linking in various areas such as literature mining, graph alignment, information retrieval, question-answering, data, and knowledge integration. Although large language models (LLMs) have made…

计算与语言 · 计算机科学 2023-07-04 Qinyong Wang , Zhenxiang Gao , Rong Xu

Recently, the increasing demand for superior medical services has highlighted the discrepancies in the medical infrastructure. With big data, especially texts, forming the foundation of medical services, there is an exigent need for…

计算与语言 · 计算机科学 2024-07-17 Yuanhe Tian , Ruyi Gan , Yan Song , Jiaxing Zhang , Yongdong Zhang

Named entity recognition is a key component of Information Extraction (IE), particularly in scientific domains such as biomedicine and chemistry, where large language models (LLMs), e.g., ChatGPT, fall short. We investigate the…

计算与语言 · 计算机科学 2024-04-02 Hongyi Liu , Qingyun Wang , Payam Karisani , Heng Ji

Transformer based pre-trained models such as BERT and its variants, which are trained on large corpora, have demonstrated tremendous success for natural language processing (NLP) tasks. Most of academic works are based on the English…

计算与语言 · 计算机科学 2023-06-27 Muhammed Cihat Ünal , Betül Aygün , Aydın Gerek

We explore how continued pre-training on domain-specific corpora influences large language models, revealing that training on the raw corpora endows the model with domain knowledge, but drastically hurts its prompting ability for question…

计算与语言 · 计算机科学 2024-07-26 Daixuan Cheng , Shaohan Huang , Furu Wei

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse…

机器学习 · 计算机科学 2025-05-09 Jialu Tang , Tong Xia , Yuan Lu , Cecilia Mascolo , Aaqib Saeed

Objective: Clinical knowledge enriched transformer models (e.g., ClinicalBERT) have state-of-the-art results on clinical NLP (natural language processing) tasks. One of the core limitations of these transformer models is the substantial…

计算与语言 · 计算机科学 2023-01-30 Yikuan Li , Ramsey M. Wehbe , Faraz S. Ahmad , Hanyin Wang , Yuan Luo

Recent years have seen particular interest in using electronic medical records (EMRs) for secondary purposes to enhance the quality and safety of healthcare delivery. EMRs tend to contain large amounts of valuable clinical notes. Learning…

计算与语言 · 计算机科学 2022-07-25 Hoda Memarzadeh , Nasser Ghadiri , Maryam Lotfi Shahreza

Although biomedical entity linking (BioEL) has made significant progress with pre-trained language models, challenges still exist for fine-grained and long-tailed entities. To address these challenges, we present BioELQA, a novel model that…

计算与语言 · 计算机科学 2024-05-20 Zhenxi Lin , Ziheng Zhang , Xian Wu , Yefeng Zheng

Most existing methods for biomedical entity recognition task rely on explicit feature engineering where many features either are specific to a particular task or depends on output of other existing NLP tools. Neural architectures have been…

计算与语言 · 计算机科学 2017-08-14 Sunil Kumar Sahu , Ashish Anand

Advances in English language representation enabled a more sample-efficient pre-training task by Efficiently Learning an Encoder that Classifies Token Replacements Accurately (ELECTRA). Which, instead of training a model to recover masked…

计算与语言 · 计算机科学 2021-03-09 Wissam Antoun , Fady Baly , Hazem Hajj

Clinical electroencephalogram (EEG) reports encode domain-specific linguistic conventions that general-purpose language models (LMs) fail to capture. We introduce NeuroLex, a lightweight domain-adaptive language model trained purely on EEG…

计算与语言 · 计算机科学 2025-11-18 Kang Yin , Hye-Bin Shin

Clinical Named Entity Recognition (CNER) aims to identify and classify clinical terms such as diseases, symptoms, treatments, exams, and body parts in electronic health records, which is a fundamental and crucial task for clinical and…

计算与语言 · 计算机科学 2018-04-16 Qi Wang , Yuhang Xia , Yangming Zhou , Tong Ruan , Daqi Gao , Ping He