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Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…

图像与视频处理 · 电气工程与系统科学 2024-12-10 Mozhgan Naderi , Maryam Rastgarpour , Amir Reza Takhsha

As societies around the world are ageing, the number of Alzheimer's disease (AD) patients is rapidly increasing. To date, no low-cost, non-invasive biomarkers have been established to advance the objectivization of AD diagnosis and…

Recent breakthroughs in Automatic Speech Recognition (ASR) have enabled fully automated Alzheimer's Disease (AD) detection using ASR transcripts. Nonetheless, the impact of ASR errors on AD detection remains poorly understood. This paper…

音频与语音处理 · 电气工程与系统科学 2025-05-27 Yin-Long Liu , Rui Feng , Jia-Xin Chen , Yi-Ming Wang , Jia-Hong Yuan , Zhen-Hua Ling

Alzheimer's dementia (AD) is of increasing concern as populations achieve longer lifespans. Many of the recent failed AD clinical trials recruiting cognitively intact individuals had a low number of AD events and were thus underpowered.…

统计方法学 · 统计学 2025-03-21 Julia Gallini , Zach Baucom , Yorghos Tripodis

It is acknowledged that the most common cause of dementia worldwide is Alzheimer's disease (AD). This condition progresses in severity from mild to severe and interferes with people's everyday routines. Early diagnosis plays a critical role…

图像与视频处理 · 电气工程与系统科学 2024-09-30 Sajjad Aghasi Javid , Mahmood Mohassel Feghhi

Progressive cognitive decline spanning across decades is characteristic of Alzheimer's disease (AD). Various predictive models have been designed to realize its early onset and study the long-term trajectories of cognitive test scores…

Current work on speech-based dementia assessment focuses on either feature extraction to predict assessment scales, or on the automation of existing test procedures. Most research uses public data unquestioningly and rarely performs a…

音频与语音处理 · 电气工程与系统科学 2025-08-07 Franziska Braun , Christopher Witzl , Andreas Erzigkeit , Hartmut Lehfeld , Thomas Hillemacher , Tobias Bocklet , Korbinian Riedhammer

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power…

机器学习 · 计算机科学 2025-11-11 Richard Hou , Shengpu Tang , Wei Jin

Conversational speech often reveals early signs of cognitive decline, such as dementia and MCI. In the UK, one in four people belongs to an ethnic minority, and dementia prevalence is expected to rise most rapidly among Black and Asian…

Alzheimer's disease (AD) and its prodromal stage, Mild Cognitive Impairment (MCI), are associated with subtle declines in memory, attention, and language that often go undetected until late in progression. Traditional diagnostic tools such…

人机交互 · 计算机科学 2025-12-30 Ananya Drishti , Mahfuza Farooque

This paper proposes a speech-based method for automatic depression classification. The system is based on ensemble learning for Convolutional Neural Networks (CNNs) and is evaluated using the data and the experimental protocol provided in…

音频与语音处理 · 电气工程与系统科学 2024-02-06 Adrián Vázquez-Romero , Ascensión Gallardo-Antolín

As shown in computer vision, the power of deep learning lies in automatically learning relevant and powerful features for any perdition task, which is made possible through end-to-end architectures. However, deep learning approaches applied…

计算机视觉与模式识别 · 计算机科学 2018-10-02 Soheil Esmaeilzadeh , Dimitrios Ioannis Belivanis , Kilian M. Pohl , Ehsan Adeli

Agitation is one of the most prevalent symptoms in people with dementia (PwD) that can place themselves and the caregiver's safety at risk. Developing objective agitation detection approaches is important to support health and safety of PwD…

机器学习 · 计算机科学 2023-08-16 Zhidong Meng , Andrea Iaboni , Bing Ye , Kristine Newman , Alex Mihailidis , Zhihong Deng , Shehroz S. Khan

Research related to automatically detecting Alzheimer's disease (AD) is important, given the high prevalence of AD and the high cost of traditional methods. Since AD significantly affects the acoustics of spontaneous speech, speech…

声音 · 计算机科学 2022-09-15 Jekaterina Novikova

Alzheimer's Disease (AD), as the most devastating neurodegenerative disease worldwide, has reached nearly 10 million new cases annually. Current technology provides unprecedented opportunities to study the progression and etiology of this…

神经元与认知 · 定量生物学 2022-11-14 Zibin Zhao

Autism spectrum disorder (ASD) is a neurodevelopmental disorder which results in altered behavior, social development, and communication patterns. In past years, autism prevalence has tripled, with 1 in 54 children now affected. Given that…

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

计算机视觉与模式识别 · 计算机科学 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Predicting the risk of clinical progression from cognitively normal (CN) status to mild cognitive impairment (MCI) or Alzheimer's disease (AD) is critical for early intervention in Alzheimer's disease (AD). Traditional survival models often…

应用统计 · 统计学 2025-03-24 Dhrubajyoti Ghosh , Samhita Pal , Michael Lutz , Sheng Luo

The ability to accurately detect onset of dementia is important in the treatment of the disease. Clinically, the diagnosis of Alzheimer Disease (AD) and Mild Cognitive Impairment (MCI) patients are based on an integrated assessment of…

信号处理 · 电气工程与系统科学 2022-11-18 Wan-Ting Hsieh , Jeremy Lefort-Besnard , Hao-Chun Yang , Li-Wei Kuo , Chi-Chun Lee

This paper presents our submission to the PROCESS Challenge 2025, focusing on spontaneous speech analysis for early dementia detection. For the three-class classification task (Healthy Control, Mild Cognitive Impairment, and Dementia), we…

音频与语音处理 · 电气工程与系统科学 2025-05-28 Yin-Long Liu , Yuanchao Li , Rui Feng , Liu He , Jia-Xin Chen , Yi-Ming Wang , Yu-Ang Chen , Yan-Han Peng , Jia-Hong Yuan , Zhen-Hua Ling