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Alzheimer's disease (AD) constitutes a neurodegenerative disease with serious consequences to peoples' everyday lives, if it is not diagnosed early since there is no available cure. Alzheimer's is the most common cause of dementia, which…

计算与语言 · 计算机科学 2023-01-18 Loukas Ilias , Dimitris Askounis , John Psarras

Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

定量方法 · 定量生物学 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

Mild Cognitive Impairment (MCI) is an early stage of Alzheimer's disease (AD), a form of neurodegenerative disorder. Early identification of MCI is crucial for delaying its progression through timely interventions. Existing research has…

音频与语音处理 · 电气工程与系统科学 2024-10-18 Kristin Qi , Jiatong Shi , Caroline Summerour , John A. Batsis , Xiaohui Liang

Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

机器学习 · 计算机科学 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…

音频与语音处理 · 电气工程与系统科学 2025-09-29 Jiawen Kang , Dongrui Han , Lingwei Meng , Jingyan Zhou , Jinchao Li , Xixin Wu , Helen Meng

Alzheimer's Dementia (AD) is an incurable, debilitating, and progressive neurodegenerative condition that affects cognitive function. Early diagnosis is important as therapeutics can delay progression and give those diagnosed vital time.…

机器学习 · 计算机科学 2023-02-28 Thomas Searle , Zina Ibrahim , Richard Dobson

Alzheimer's disease (AD) is the main cause of dementia which is accompanied by loss of memory and may lead to severe consequences in peoples' everyday life if not diagnosed on time. Very few works have exploited transformer-based networks…

计算与语言 · 计算机科学 2022-08-15 Loukas Ilias , Dimitris Askounis

A key issue to Alzheimer's disease clinical trial failures is poor participant selection. Participants have heterogeneous cognitive trajectories and many do not decline during trials, which reduces a study's power to detect treatment…

定量方法 · 定量生物学 2022-05-05 Angela Tam , César Laurent , Serge Gauthier , Christian Dansereau

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, structural brain changes, and genetic predispositions. This study leverages machine-learning and statistical techniques to investigate…

应用统计 · 统计学 2025-10-29 Riddhik Basu , Arkaprava Roy

Dementia, a neurodegenerative disease, alters speech patterns, creating communication barriers and raising privacy concerns. Current speech technologies, such as automatic speech transcription (ASR), struggle with dementia and atypical…

计算与语言 · 计算机科学 2025-07-15 Dominika Woszczyk , Ranya Aloufi , Soteris Demetriou

Alzheimer's disease (AD) is the most common long-term illness in elderly people. In recent years, deep learning has become popular in the area of medical imaging and has had a lot of success there. It has become the most effective way to…

计算机视觉与模式识别 · 计算机科学 2023-10-16 Mahin Khan Mahadi , Abdullah Abdullah , Jamal Uddin , Asif Newaz

Alzheimer's disease (AD) is one the main causes of dementia in the world and the patients develop severe disability and sometime full dependence. In previous stages Mild Cognitive Impairment (MCI) produces cognitive loss but not severe…

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and to delay further progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical…

计算与语言 · 计算机科学 2023-04-03 Yi Wang , Jiajun Deng , Tianzi Wang , Bo Zheng , Shoukang Hu , Xunying Liu , Helen Meng

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and delay progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical screening…

机器学习 · 计算机科学 2022-08-09 Yi Wang , Tianzi Wang , Zi Ye , Lingwei Meng , Shoukang Hu , Xixin Wu , Xunying Liu , Helen Meng

Millions of people live with cognitive impairment from Alzheimer's disease and related dementias (ADRD). Voice-enabled smart home systems offer promise for supporting daily living but rely on automatic speech recognition (ASR) to transcribe…

人机交互 · 计算机科学 2026-03-02 Michelle Cohn , Alyssa Lanzi , Yui Ishihara , Chen-Nee Chuah , Georgia Zellou , Alyssa Weakley

Several machine learning algorithms have been developed for the prediction of Alzheimer's disease and related dementia (ADRD) from spontaneous speech. However, none of these algorithms have been translated for the prediction of broader…

Dementia is a syndrome, generally of a chronic nature characterized by a deterioration in cognitive function, especially in the geriatric population and is severe enough to impact their daily activities. Early diagnosis of dementia is…

音频与语音处理 · 电气工程与系统科学 2020-07-21 Rupayan Chakraborty , Meghna Pandharipande , Chitralekha Bhat , Sunil Kumar Kopparapu

Alzheimers Disease AD is an acute neuro disease that degenerates the brain cells and thus leads to memory loss progressively. It is a fatal brain disease that mostly affects the elderly. It steers the decline of cognitive and biological…

机器学习 · 计算机科学 2023-04-20 Nair Bini Balakrishnan , P. S. Sreeja , Jisha Jose Panackal

Dementia in the elderly has recently become the most usual cause of cognitive decline. The proliferation of dementia cases in aging societies creates a remarkable economic as well as medical problems in many communities worldwide. A…

神经元与认知 · 定量生物学 2019-06-20 Tomasz M. Rutkowski , Marcin Koculak , Masato S. Abe , Mihoko Otake-Matsuura