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With the advanced imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high…

应用统计 · 统计学 2020-12-10 Esteban Fernández Morales , Cong Zhang , Guanghua Xiao , Chul Moon , Qiwei Li

Microscopy image analysis is fundamental for different applications, from diagnosis to synthetic engineering and environmental monitoring. Modern acquisition systems have granted the possibility to acquire an escalating amount of images,…

计算机视觉与模式识别 · 计算机科学 2025-06-26 Jacopo Dapueto , Vito Paolo Pastore , Nicoletta Noceti , Francesca Odone

Compared with single-label image classification, multi-label image classification is more practical and challenging. Some recent studies attempted to leverage the semantic information of categories for improving multi-label image…

计算机视觉与模式识别 · 计算机科学 2021-04-05 Fengtao Zhou , Sheng Huang , Yun Xing

Multi-modal learning plays a crucial role in cancer diagnosis and prognosis. Current deep learning based multi-modal approaches are often limited by their abilities to model the complex correlations between genomics and histology data,…

图像与视频处理 · 电气工程与系统科学 2024-06-21 Yupei Zhang , Xiaofei Wang , Fangliangzi Meng , Jin Tang , Chao Li

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

计算机视觉与模式识别 · 计算机科学 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Empirical evaluation of breast tissue biopsies for mitotic nuclei detection is considered an important prognostic biomarker in tumor grading and cancer progression. However, automated mitotic nuclei detection poses several challenges…

计算机视觉与模式识别 · 计算机科学 2020-03-20 Anabia Sohail , Muhammad Ahsan Mukhtar , Asifullah Khan , Muhammad Mohsin Zafar , Aneela Zameer , Saranjam Khan

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

图像与视频处理 · 电气工程与系统科学 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

Breast cancer has the highest mortality among cancers in women. Computer-aided pathology to analyze microscopic histopathology images for diagnosis with an increasing number of breast cancer patients can bring the cost and delays of…

计算机视觉与模式识别 · 计算机科学 2020-03-03 Abhijeet Patil , Dipesh Tamboli , Swati Meena , Deepak Anand , Amit Sethi

Deep learning (DL) has shown unprecedented performance for many image analysis and image enhancement tasks. Yet, solving large-scale inverse problems like tomographic reconstruction remains challenging for DL. These problems involve…

医学物理 · 物理学 2019-12-18 Lin Fu , Bruno De Man

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

The continually increasing number of complex datasets each year necessitates ever improving machine learning methods for robust and accurate categorization of these data. This paper introduces Random Multimodel Deep Learning (RMDL): a new…

机器学习 · 计算机科学 2018-06-01 Kamran Kowsari , Mojtaba Heidarysafa , Donald E. Brown , Kiana Jafari Meimandi , Laura E. Barnes

Phyllodes tumors (PTs) are rare fibroepithelial breast lesions that are difficult to classify preoperatively due to their radiological similarity to benign fibroadenomas. This often leads to unnecessary surgical excisions. To address this,…

计算机视觉与模式识别 · 计算机科学 2025-09-26 Farhan Fuad Abir , Abigail Elliott Daly , Kyle Anderman , Tolga Ozmen , Laura J. Brattain

Histopathology is a reflection of the molecular changes and provides prognostic phenotypes representing the disease progression. In this study, we introduced feature scores generated from hematoxylin and eosin histology images based on deep…

Early detection of cancerous tissue is crucial for long-term patient survival. In the head and neck region, a typical diagnostic procedure is an endoscopic intervention where a medical expert manually assesses tissue using RGB camera…

In recent years, computational pathology has seen tremendous progress driven by deep learning methods in segmentation and classification tasks aiding prognostic and diagnostic settings. Nuclei segmentation, for instance, is an important…

图像与视频处理 · 电气工程与系统科学 2023-03-22 Aman Shrivastava , P. Thomas Fletcher

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

计算机视觉与模式识别 · 计算机科学 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

Registration of images with pathologies is challenging due to tissue appearance changes and missing correspondences caused by the pathologies. Moreover, mass effects as observed for brain tumors may displace tissue, creating larger…

图像与视频处理 · 电气工程与系统科学 2020-08-19 Xu Han , Zhengyang Shen , Zhenlin Xu , Spyridon Bakas , Hamed Akbari , Michel Bilello , Christos Davatzikos , Marc Niethammer

Applying deep learning methods to mammography assessment has remained a challenging topic. Dense noise with sparse expressions, mega-pixel raw data resolution, lack of diverse examples have all been factors affecting performance. The lack…

计算机视觉与模式识别 · 计算机科学 2018-07-10 Ulzee An , Khader Shameer , Lakshmi Subramanian