相关论文: LinDA: linear models for differential abundance an…

Unsupervised representation learning, particularly sequential disentanglement, aims to separate static and dynamic factors of variation in data without relying on labels. This remains a challenging problem, as existing approaches based on…

We propose an instrumental variable framework for identifying and estimating causal effects of discrete and continuous treatments with binary instruments. The basis of our approach is a local copula representation of the joint distribution…

In this paper, we present an effective data augmentation framework leveraging the Large Language Model (LLM) and Diffusion Model (DM) to tackle the challenges inherent in data-scarce scenarios. Recently, DMs have opened up the possibility…

The compositionality and sparsity of high-throughput sequencing data poses a challenge for regression and classification. However, in microbiome research in particular, conditional modeling is an essential tool to investigate relationships…

We present an extension of Willems' Fundamental Lemma to the class of multi-input multi-output discrete-time feedback linearizable nonlinear systems, thus providing a data-based representation of their input-output trajectories. Two sources…

Simulating longitudinal data from specified marginal structural models is a crucial but challenging task for evaluating causal inference methods and informing study design. While data generation typically proceeds in a fully conditional…

Diffusion-based data augmentation (DiffDA) has emerged as a promising approach to improving classification performance under data scarcity. However, existing works vary significantly in task configurations, model choices, and experimental…

Navigating the complex landscape of single-cell transcriptomic data presents significant challenges. Central to this challenge is the identification of a meaningful representation of high-dimensional gene expression patterns that sheds…

Traditionally, spline or kernel approaches in combination with parametric estimation are used to infer the linear coefficient (fixed effects) in a partially linear mixed-effects model for repeated measurements. Using machine learning…

There is an increasing interest in the development of new data-driven models useful to assess the performance of communication networks. For many applications, like network monitoring and troubleshooting, a data model is of little use if it…

Inferring causal relationships from observational data is often challenging due to endogeneity. This paper provides new identification results for causal effects of discrete, ordered and continuous treatments using multiple binary…

Detecting associations between microbial compositions and sample characteristics is one of the most important tasks in microbiome studies. Most of the existing methods apply univariate models to single microbial species separately, with…

Compositional observations are an increasingly prevalent data source in spatial statistics. Analysis of such data is typically done on log-ratio transformations or via Dirichlet regression. However, these approaches often make unnecessarily…

Comparative biologists are often interested in inferring covariation between multiple biological traits sampled across numerous related taxa. To properly study these relationships, we must control for the shared evolutionary history of the…

In binary classification, imbalance refers to situations in which one class is heavily under-represented. This issue is due to either a data collection process or because one class is indeed rare in a population. Imbalanced classification…

The regression discontinuity design (RDD) is a quasi-experimental design that can be used to identify and estimate the causal effect of a treatment using observational data. In an RDD, a pre-specified rule is used for treatment assignment,…

By means of the linear parameter-varying (LPV) Fundamental Lemma, we derive novel data-driven predictive control (DPC) methods for LPV systems. In particular, we present output-feedback and state-feedback-based LPV-DPC methods with terminal…

Linear discriminant analysis (LDA), a traditional classification tool, suffers from limitations such as sensitivity to noise and computational challenges when dealing with non-invertible within-class scatter matrices. Traditional stepwise…

Advances in data collection are producing growing volumes of temporal count observations, making adapted modeling increasingly necessary. In this work, we introduce a generative framework for independent component analysis of temporal count…

A new method is proposed to perform joint analysis of longitudinal and cross-sectional growth data. Clustering is first performed to group similar subjects in cross-sectional data to form a pseudo longitudinal data set, then the pseudo…